Delineating the Complex Genomic Landscape

Ivan September 9, 2020 0 Comments
myasthenickids

Delineating the Complex Genomic Landscape of Multiple Myeloma Using Next-Generation Sequencing (NGS): Progress and Potential to Supersede Traditional Genetic Testing

  • Recent NGS studies in multiple myeloma identified in one step and with comparable high accuracy to the concurrent cytogenomic tests the characteristic IGH translocations and copy number abnormalities. In addition, NGS allowed detection of gene mutations.
  • This unprecedented success of a comprehensive genomic analysis suggests the possibility of replacing the separate tests in current use (cytogenetics, FISH, SNPs microarray and mutation analysis) with a single more efficient NGS assay. Down the road, NGS appears to have the potential to improve routine patient care with the clinical application of a detailed genomic profile.
myasthenickids
myasthenickids

LIF, Mouse
HY-P7084 50ug
EUR 639.6

LIF, mouse
MO16102 100 ug
EUR 810

LIF, Mouse
MBS8575391-0005mg 0.005mg
EUR 245

LIF, Mouse
MBS8575391-5x0005mg 5x0.005mg
EUR 940

Mouse Anti-Human LIF Monoclonal Antibody
MBS592457-01mg 0.1mg
EUR 365

Mouse Anti-Human LIF Monoclonal Antibody
MBS592457-05mg 0.5mg
EUR 530

Mouse Anti-Human LIF Monoclonal Antibody
MBS592457-5x05mg 5x0.5mg
EUR 2140

Mouse Anti-Human LIF Monoclonal Antibody
MBS592458-01mg 0.1mg
EUR 365

Mouse Anti-Human LIF Monoclonal Antibody
MBS592458-05mg 0.5mg
EUR 530

Mouse Anti-Human LIF Monoclonal Antibody
MBS592458-5x05mg 5x0.5mg
EUR 2140

Mouse Anti-Human LIF Monoclonal Antibody
MBS592459-01mg 0.1mg
EUR 365

Mouse Anti-Human LIF Monoclonal Antibody
MBS592459-05mg 0.5mg
EUR 530

Mouse Anti-Human LIF Monoclonal Antibody
MBS592459-5x05mg 5x0.5mg
EUR 2140

Mouse LIF Protein
E40MOP1672 20ug
EUR 495

Mouse LIF Protein
E40MOP2026 20ug
EUR 495

Mouse LIF Protein
E40MOP2028 20ug
EUR 495

LIF, Mouse, Monoclonal Antibody, Mouse
MBS555093-01mg 0.1mg
EUR 745

LIF, Mouse, Monoclonal Antibody, Mouse
MBS555093-5x01mg 5x0.1mg
EUR 3210

LIF siRNA (Mouse)
MBS8224619-15nmol 15nmol
EUR 405

LIF siRNA (Mouse)
MBS8224619-30nmol 30nmol
EUR 565

LIF siRNA (Mouse)
MBS8224619-5x30nmol 5x30nmol
EUR 2450

Recombinant Mouse LIF
Z200195 10 µg
EUR 85
Description: LIF is a multifunctional secreted glycoprotein that exists in both soluble and matrix-bound forms. It displays biologic activities ranging from the differentiation of myeloid leukemic cells into macrophage lineage to effects on bone metabolism, inflammation, neural development, embryogenesis, and the maintenance of implantation. It is now clear that LIF is related in both structure and mechanism of action to the interleukin IL-6 family of cytokines, which also includes IL-11, ciliary neurotrophic factor, oncostatin M, and cardiotrophin 1. The actions of these cytokines are mediated through specific cell-surface receptors that consist of a unique chain and the shared signal transducing subunit gp130.

Recombinant Mouse LIF
Z200197 100 µg
EUR 385
Description: LIF is a multifunctional secreted glycoprotein that exists in both soluble and matrix-bound forms. It displays biologic activities ranging from the differentiation of myeloid leukemic cells into macrophage lineage to effects on bone metabolism, inflammation, neural development, embryogenesis, and the maintenance of implantation. It is now clear that LIF is related in both structure and mechanism of action to the interleukin IL-6 family of cytokines, which also includes IL-11, ciliary neurotrophic factor, oncostatin M, and cardiotrophin 1. The actions of these cytokines are mediated through specific cell-surface receptors that consist of a unique chain and the shared signal transducing subunit gp130.

Recombinant Mouse LIF
Z200199 1.0 mg
EUR 1200
Description: LIF is a multifunctional secreted glycoprotein that exists in both soluble and matrix-bound forms. It displays biologic activities ranging from the differentiation of myeloid leukemic cells into macrophage lineage to effects on bone metabolism, inflammation, neural development, embryogenesis, and the maintenance of implantation (2). It is now clear that LIF is related in both structure and mechanism of action to the interleukin IL-6 family of cytokines, which also includes IL-11, ciliary neurotrophic factor, oncostatin M, and cardiotrophin 1 (2). The actions of these cytokines are mediated through specific cell-surface receptors that consist of a unique chain and the shared signal transducing subunit gp130.

Recombinant Mouse LIF
Z200485 100 µg
EUR 1500
Description: LIF is a multifunctional secreted glycoprotein that exists in both soluble and matrix-bound forms. It displays biologic activities ranging from the differentiation of myeloid leukemic cells into macrophage lineage to effects on bone metabolism, inflammation, neural development, embryogenesis, and the maintenance of implantation (2). It is now clear that LIF is related in both structure and mechanism of action to the interleukin IL-6 family of cytokines, which also includes IL-11, ciliary neurotrophic factor, oncostatin M, and cardiotrophin 1 (2). The actions of these cytokines are mediated through specific cell-surface receptors that consist of a unique chain and the shared signal transducing subunit gp130.

Recombinant Mouse LIF
MBS7609292-005mg 0.05mg
EUR 405

Recombinant Mouse LIF
MBS7609292-02mg 0.2mg
EUR 760

Recombinant Mouse LIF
MBS7609292-1mg 1mg
EUR 2175

Recombinant Mouse LIF
MBS7609292-5x1mg 5x1mg
EUR 8410

Recombinant Mouse LIF
MBS4159936-001mg 0.01mg
EUR 230

Recombinant Mouse LIF
MBS4159936-01mg 0.1mg
EUR 560

Recombinant Mouse LIF
MBS4159936-1mg 1mg
EUR 1500

Recombinant Mouse LIF
MBS4159936-5x1mg 5x1mg
EUR 6500

Recombinant Mouse LIF
P1174-.005 5ug
EUR 108.8
Description: Peptides & Proteins|Recombinant Proteins

Recombinant Mouse LIF
P1174-.1 100ug
EUR 840.8
Description: Peptides & Proteins|Recombinant Proteins

Recombinant Mouse LIF
P1174-.5 500ug
EUR 1885.6
Description: Peptides & Proteins|Recombinant Proteins

Anti-Mouse LIF Antibody
103-M263 100 µg
EUR 399
Description: Based on its helical structure, LIF (Leukemia Inhibitory Factor) is considered a member of the Interleukin-6 family of cytokines. Functionally, it has been implicated in a many physiological processes including development, hematopoiesis, bone metabolism, and inflammation. Some cell types known to express LIF include activated T cells, monocytes, astrocytes, osteoblasts, keratinocytes, regenerating skeletal muscle, mast cells, and fibroblasts.

Anti-Mouse LIF Antibody
103-PA05S 100 µg
EUR 126
Description: Leukemia Inhibitory Factor also called LIF is a lymphoid factor that promotes long-term maintenance of embryonic stem cells by suppressing spontaneous differentiation. Leukemia Inhibitory Factor has several functions such as cholinergic neuron differentiation, control of stem cell pluripotency, bone & fat metabolism, mitogenesis of factor dependent cell lines & promotion of megakaryocyte production in vivo. Human and mouse LIF exhibit a 78% identity in its amino acid sequence. Human LIF is as active on human cells as is it is on mouse cells, though mouse LIF is about 1000 fold less active on human cells, than human LIF.

Rabbit Anti-Mouse LIF
103-PA05 100ug
EUR 240

LIF (mouse), (recombinant)
MBS566073-1mL 1mL
EUR 1470

LIF (mouse), (recombinant)
MBS566073-5x1mL 5x1mL
EUR 6555

Mouse LIF ELISA Kit
E28L0650 96T
EUR 666.67

Mouse LIF ELISA Kit
EK5250 96 tests
EUR 599

Mouse Lif ELISA Kit
EF012949 96tests
EUR 566

Mouse LIF ELISA Kit
EML0014 96Tests
EUR 625.2

Mouse LIF shRNA Plasmid
20-abx971321
  • Ask for price
  • Ask for price
  • 150 µg
  • 300 µg

LIF, Human, Monoclonal Antibody, Mouse
MBS555094-01mg 0.1mg
EUR 745

LIF, Human, Monoclonal Antibody, Mouse
MBS555094-5x01mg 5x0.1mg
EUR 3210

Recombinant Mouse LIF protein
IMP-1308 10µg
EUR 360
Description: Recombinant Proteins

Mouse LIF Recombinant Protein
M30-007 10 µg
EUR 99.75
Description: Leukemia Inhibitory Factor also called LIF is a lymphoid factor that promotes long-term maintenance of embryonic stem cells by suppressing spontaneous differentiation. Leukemia Inhibitory Factor has several functions such as cholinergic neuron differentiation, control of stem cell pluripotency, bone & fat metabolism, mitogenesis of factor dependent cell lines & promotion of megakaryocyte production in vivo. Human and mouse LIF exhibit a 78% identity in its amino acid sequence. Human LIF is as active on human cells as is it is on mouse cells, though mouse LIF is about 1000 fold less active on human cells, than human LIF. Recombinant mouse LIF produced in E. coli is a single, non-glycosylated, polypeptide chain containing 180 amino acids and having a molecular mass of 19.86 kDa.

Mouse LIF Recombinant Protein
M30-008 50 µg
EUR 246.75
Description: Leukemia Inhibitory Factor also called LIF is a lymphoid factor that promotes long-term maintenance of embryonic stem cells by suppressing spontaneous differentiation. Leukemia Inhibitory Factor has several functions such as cholinergic neuron differentiation, control of stem cell pluripotency, bone & fat metabolism, mitogenesis of factor dependent cell lines & promotion of megakaryocyte production in vivo. Human and mouse LIF exhibit a 78% identity in its amino acid sequence. Human LIF is as active on human cells as is it is on mouse cells, though mouse LIF is about 1000 fold less active on human cells, than human LIF. Recombinant mouse LIF produced in E. coli is a single, non-glycosylated, polypeptide chain containing 180 amino acids and having a molecular mass of 19.86 kDa.

Recombinant Mouse LIF Protein
R01400-1 100ug/vial
EUR 352.8

Recombinant Mouse LIF protein
CD00323-5ug 5ug
EUR 176
Description: Leukemia inhibitory factor (LIF) is a member of Interleukin 6 family. This protein is mainly expressed in the trophectoderm of the developing embryo, with its receptor LIFR expressed throughout the inner cell mass. LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes. LIF is used in mouse embryonic stem cell culture, because that removal of LIF pushes stem cells toward differentiation, but they retain their proliferative potential or pluripotency. It is also used in phase II clinical trial, which can assist embryo implantation in women who have failed to become pregnant despite assisted reproductive technologies (ART). Mature mouse LIF shares 78 % a.a. sequence identity with Human LIF.

Recombinant Mouse LIF Protein
PKSM041100-100ug 100ug
EUR 739
Description: Mouse

Recombinant Mouse LIF Protein
PKSM041100-20ug 20ug
EUR 249
Description: Mouse

Recombinant Mouse LIF Protein
MBS8249390-001mg 0.01mg
EUR 230

Recombinant Mouse LIF Protein
MBS8249390-005mg 0.05mg
EUR 480

Recombinant Mouse LIF Protein
MBS8249390-05mg 0.5mg
EUR 2825

Recombinant Mouse LIF Protein
MBS8249390-5x05mg 5x0.5mg
EUR 12640

Recombinant Mouse LIF Protein
MBS1751002-01mg 0.1mg
EUR 315

Recombinant Mouse LIF Protein
MBS1751002-5x01mg 5x0.1mg
EUR 1270

Rat Monoclonal anti-mouse LIF
mAP-0122 100ug
EUR 250

Sheep Polyclonal anti-mouse LIF
mAP-5260 50ug
EUR 400

Anti-LIF Antibody, Mouse Monoclonal
MBS8107490-01mL 0.1mL
EUR 300

Anti-LIF Antibody, Mouse Monoclonal
MBS8107490-5x01mL 5x0.1mL
EUR 1200

anti- LIF antibody
LSMab09804 100ug
EUR 275

anti- LIF antibody
FNab09804 100µg
EUR 658.5
Description: Antibody raised against LIF

Mouse LIF PicoKine ELISA Kit
EK0580 96 wells
EUR 510
Description: For quantitative detection of mouse LIF in cell culture supernates, serum and plasma (heparin, EDTA).

Mouse LIF PicoKine ELISA Kit
MBS178717-5x96StripWells 5x96-Strip-Wells
EUR 2755

Mouse LIF PicoKine ELISA Kit
MBS178717-96StripWells 96-Strip-Wells
EUR 600

LIF mouse monoclonal antibody, clone 4F7.2
MO16101-100 100 µg Ask for price

LIF mouse monoclonal antibody, clone 2H2.2
MO16102-100 100 µg Ask for price

Recombinant Mouse LIF, Tag Free
PM2019-.01 10ug
EUR 208
Description: Peptides & Proteins|Recombinant Proteins

Recombinant Mouse LIF, Tag Free
PM2019-.1 10X10ug
EUR 784
Description: Peptides & Proteins|Recombinant Proteins

Lif ORF Vector (Mouse) (pORF)
ORF049145 1.0 ug DNA
EUR 607.2

Lif ORF Vector (Mouse) (pORF)
ORF049146 1.0 ug DNA
EUR 607.2

LIF ELISA Kit (Mouse) (OKBB00760)
OKBB00760 96 Wells
EUR 606
Description: Description of target: Leukemia inhibitory factor, or LIF, is an interleukin 6 class cytokine that affects cell growth by inhibiting differentiation. When LIF levels drop, the cells differentiate. The LIF was mapped gene to 22q11-q12.2 by Southern analysis of a series of mouse/human somatic cell hybrids and by in situ hybridization to the chromosomes of 2 normal males and some individuals with chromosomal rearrangements. The gene maps between the Philadelphia translocation BCR1 and the breakpoint of the translocation in cell line GM2324 at 22q12.2. LIF derives its name from its ability to induce the terminal differentiation of myeloid leukemic cells, thus preventing their continued growth. Other properties attributed to the cytokine include: the growth promotion and cell differentiation of different types of target cells, influence on bone metabolism, cachexia, neural development, embryogenesis and inflammation.;Species reactivity: Mouse;Application: ELISA;Assay info: ;Sensitivity: <10pg/ml

LIF, Mouse Recombinant , 1MIU/ml
L4500-001 1ml
EUR 406.8

LIF, Mouse Recombinant , 1MIU/ml
L4500-005 5x1ml
EUR 1431.6

LIF ELISA Kit (Mouse) (OKEH04045)
OKEH04045 96 Wells
EUR 652.8
Description: Description of target: LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.039 ng/mL

LIF, Mouse Recombinant , 10MIU/ml
L4501-001 1ml
EUR 1744.8

Mouse LIF HEK293 Overexpression Lysate
MBS8119752-03mg 0.3mg
EUR 280

Mouse LIF HEK293 Overexpression Lysate
MBS8119752-5x03mg 5x0.3mg
EUR 1205

Mouse LIF HEK293 Overexpression Lysate
MBS8119753-03mg 0.3mg
EUR 280

Mouse LIF HEK293 Overexpression Lysate
MBS8119753-5x03mg 5x0.3mg
EUR 1205

Purified recombinant Mouse LIF protein
MBS5308803-001mg 0.01mg
EUR 550

Purified recombinant Mouse LIF protein
MBS5308803-5x001mg 5x0.01mg
EUR 2435

LIFR, Recombinant, Mouse (Leukemia Inhibitory Factor Receptor, LIF Receptor, LIF-R, D-factor/LIF Receptor, CD118)
MBS636029-005mg 0.05mg
EUR 800

LIFR, Recombinant, Mouse (Leukemia Inhibitory Factor Receptor, LIF Receptor, LIF-R, D-factor/LIF Receptor, CD118)
MBS636029-5x005mg 5x0.05mg
EUR 3455

Mouse LIF Recombinant Protein Lyophilized
IMSLIFRLY5UG each
EUR 317
Description: Mouse LIF Recombinant Protein Lyophilized

Mouse LIF Recombinant Protein Lyophilized
MBS8434242-INQUIRE INQUIRE Ask for price

Nori® Mouse LIF ELISA Kit
GR117058 96-well
EUR 461

Human CellExp? LIF, mouse recombinant
7268-10 each
EUR 444

Leukemia Inhibitory Factor (LIF), mouse
PR16102 5 ug
EUR 522

Leukemia Inhibitory Factor (LIF), mouse
PR16102-B each
EUR 436.5

Leukemia Inhibitory Factor (LIF), Mouse
MBS555550-0005mg 0.005mg
EUR 500

Predictive molecular pathology of lung cancer in Germany with focus on gene fusion testing: Methods and quality assurance

Predictive molecular testing has become an important part of the diagnosis of any patient with lung cancer. Using reliable methods to ensure timely and accurate results is inevitable for guiding treatment decisions.
In the past few years, parallel sequencing has been established for mutation testing, and its use is currently broadened for the detection of other genetic alterations, such as gene fusion and copy number variations.
In addition, conventional methods such as immunohistochemistry and in situ hybridization are still being used, either for formalin-fixed, paraffin-embedded tissue or for cytological specimens. For the development and broad implementation of such complex technologies, interdisciplinary and regional networks are needed.
The Network Genomic Medicine (NGM) has served as a model of centralized testing and decentralized treatment of patients and incorporates all German comprehensive cancer centers. Internal quality control, laboratory accreditation, and participation in external quality assessment is mandatory for the delivery of reliable results.
Here, we provide a summary of current technologies used to identify patients who have lung cancer with gene fusions, briefly describe the structures of NGM and the national NGM (nNGM), and provide recommendations for quality assurance.

GeneticTesting for the Clinician in Prostate Cancer

Introduction: Prostate cancer (PCa) is one of the most common cancers worldwide and a leading cause of cancer-related mortality. Although the diagnosis and treatment of prostate cancer has improved substantially in recent years, new molecular biomarkers are needed to further prolong survival and improve quality of life in these patients.
Areas covered: This review analyses the current evidence for prognostic and predictive molecular biomarkers that can be applied across different clinical scenarios, ranging from localized disease to metastatic castration-resistant PCa, with a particular emphasis on the biomarkers likely to become available in routine clinical practice in the near future.
Expert opinion: There is a growing need for molecular testing to identify the most indolent types of prostate cancer to help optimize treatment strategies and spare treatment in these patients when possible. Current trends in the treatment of prostate cancer underscore the unmet clinical need for biomarkers to improve decision-making in a challenging clinical setting.

Identification of disease-causing variants by comprehensive genetictesting with exome sequencing in adults with suspicion of hereditary FSGS

In about 30% of infantile, juvenile, or adolescent patients with steroid-resistant nephrotic syndrome (SRNS), a monogenic cause can be identified. The histological finding in SRNS is often focal segmental glomerulosclerosis (FSGS). Genetic data on adult patients are scarce with low diagnostic yields.
Exome sequencing (ES) was performed in patients with adult disease onset and a high likelihood for hereditary FSGS. A high likelihood was defined if at least one of the following criteria was present: absence of a secondary cause, ≤25 years of age at initial manifestation, kidney biopsy with suspicion of a hereditary cause, extrarenal manifestations, and/or positive familial history/reported consanguinity. Patients were excluded if age at disease onset was <18 years. In 7/24 index patients with adult disease onset, a disease-causing variant could be identified by ES leading to a diagnostic yield of 29%. Eight different variants were identified in six known genes associated with monogenic kidney diseases.
Six of these variants had been described before as disease-causing. In patients with a disease-causing variant, the median age at disease onset and end-stage renal disease was 26 and 38 years, respectively. The overall median time to a definite genetic diagnosis was 9 years. In 29% of patients with adult disease onset and suspected hereditary FSGS, a monogenic cause could be identified.
The long delay up to the definite genetic diagnosis highlights the importance of obtaining an early genetic diagnosis to allow for personalized treatment options including weaning of immunosuppressive treatment, avoidance of repeated renal biopsy, and provision of accurate genetic counseling.

Human IL-17 protein
PRP100290-1mg 1 mg
EUR 6249
Description: Human IL-17 protein, expressed in CHO Stable Cells

Human IL-17 protein
PRP100290-5ug 5 μg
EUR 129
Description: Human IL-17 protein, expressed in CHO Stable Cells

Human IL-17 Protein
MBS9718710-0005mg 0.005mg
EUR 165

Human IL-17 Protein
MBS9718710-002mg 0.02mg
EUR 240

Human IL-17 Protein
MBS9718710-01mg 0.1mg
EUR 720

Human IL-17 Protein
MBS9718710-5x01mg 5x0.1mg
EUR 3195

Human IL-17 Protein
MBS9718711-0005mg 0.005mg
EUR 135

Human IL-17 Protein
MBS9718711-002mg 0.02mg
EUR 240

Human IL-17 Protein
MBS9718711-01mg 0.1mg
EUR 720

Human IL-17 Protein
MBS9718711-1mg 1mg
EUR 4090

Human IL-17 Protein
MBS9718711-5x1mg 5x1mg
EUR 18370

Recombinant Human IL-17
HEILP-1702 5ug Ask for price

Recombinant Human IL-17
SJB09-03 25µg/vial
EUR 307.2

anti- IL-17 antibody
FNab04224 100µg
EUR 658.5
Description: Antibody raised against IL-17

anti- IL-17 antibody
FNab04225 100µg
EUR 606.3
Description: Antibody raised against IL-17

Anti-IL-17 Antibody
ER1706-91 100ul
EUR 189
Description: Cytokines are small, soluble proteins with pleiotropic effects on a variety of cell types. Cytokines have a regulatory function over the immune system and mediate aspects of inflammatory response. They exert their biological effects through the binding of membrane-bound receptors which, in turn, initiate signal transduction cascades and elicit physiological changes in their target cell. Interleukin-17 (IL-17) and its cognate receptor, IL-17R, are an example of such a cytokine receptor pair. Originally identified as a rodent cDNA termed CTLA8, IL-17 is capable of inducing the secretion of IL-6 and IL-8 and augmenting the expression of ICAM-1 in human fibroblast cultures. The IL-17 protein exhibits a striking degree of homology with the HSV13 protein which mimics its function. The IL-17 receptor is a type I transmembrane protein 864 amino acids in length, that is highly expressed in spleen and kidney.

Anti-IL-17 Antibody
MBS822178-003mL 0.03mL
EUR 185

Anti-IL-17 Antibody
MBS822178-01mL 0.1mL
EUR 255

Anti-IL-17 Antibody
MBS822178-02mL 0.2mL
EUR 335

Anti-IL-17 Antibody
MBS822178-5x02mL 5x0.2mL
EUR 1420

Anti-IL-17 antibody
PAab04224 100ug
EUR 275

Anti-IL-17 antibody
PAab04225 100ug
EUR 245

Anti-Human IL-17 receptor Antibody
101-M484 100 µg
EUR 399
Description: IL-17 binds to IL-17 receptors (IL-17 R), which share no homology with any known family of receptors. While the expression of IL-17 is restricted to activated T cells, IL-17 R mRNA exhibits a broad tissue distribution, and has been detected in virtually all cells and tissues tested. The amino acid sequence of human IL-17 R is 69% identical to mouse IL-17 R.

Human Interleukin 17 (IL-17) CLIA Kit
abx195860-96tests 96 tests
EUR 990

Human IL-17 -Interleukin 17- CLIA Kit
E-CL-H0104-24Tests 24 Tests
EUR 180
Description: Sandwich

Human IL-17 -Interleukin 17- CLIA Kit
E-CL-H0104-48Tests 48 Tests
EUR 546
Description: Sandwich

Human IL-17 -Interleukin 17- CLIA Kit
E-CL-H0104-96Tests 96 Tests
EUR 682
Description: Sandwich

Human IL-17 -Interleukin 17- CLIA Kit
E-CL-H0104-96Tests10 96 Tests *10
EUR 6820
Description: Sandwich

Human IL-17 -Interleukin 17- CLIA Kit
E-CL-H0104-96Tests5 96 Tests *5
EUR 3410
Description: Sandwich

Human IL-17 (Interleukin 17) CLIA Kit
MBS2532901-5x96Tests 5x96Tests
EUR 2565

Human IL-17 (Interleukin 17) CLIA Kit
MBS2532901-96Tests 96Tests
EUR 560

Human IL-17 (Interleukin 17) ELISA Kit
EKE60099-5x96T 5x96T
EUR 2667.6

Human IL-17 (Interleukin 17) ELISA Kit
EKE60099-96T 96T
EUR 561.6

Human Interleukin 17(IL-17) Elisa Kit
EK711084 96 Wells
EUR 0.14

Human IL-17(Interleukin 17) ELISA Kit
E39EH3267 96T
EUR 595

Human Interleukin 17,IL-17 ELISA Kit
CN-03335H1 96T
EUR 520.8

Human Interleukin 17,IL-17 ELISA Kit
CN-03335H2 48T
EUR 340.8

Human Interleukin 17,IL-17 ELISA Kit
YLA1538HU-48T 48T Ask for price

Human Interleukin 17,IL-17 ELISA Kit
YLA1538HU-96T 96T Ask for price

Human Interleukin 17(IL-17)ELISA Kit
GA-E0081HM-48Tests 48 Tests Ask for price

Human Interleukin 17(IL-17)ELISA Kit
GA-E0081HM-96Tests 96 Tests
EUR 388

Human Interleukin 17(IL-17)ELISA Kit
GA-E0081HM-48T 48T
EUR 346.8

Human Interleukin 17(IL-17)ELISA Kit
GA-E0081HM-96T 96T
EUR 559.2

Human Interleukin 17(IL-17) ELISA Kit
NSL1920Hu 96 wells
EUR 468

Human Interleukin 17(IL-17)ELISA Kit
QY-E04323 96T
EUR 433.2

Human Interleukin 17,IL-17 ELISA Kit
SL0978Hu 96 Tests
EUR 468

Human Interleukin 17,IL-17 ELISA KIT
E0142Hu-1096T 10*96T
EUR 4122

Human Interleukin 17,IL-17 ELISA KIT
E0142Hu-48wells 48 wells
EUR 300

Human Interleukin 17,IL-17 ELISA KIT
E0142Hu-596T 5*96T
EUR 2061

Human Interleukin 17,IL-17 ELISA KIT
E0142Hu-96wells 96 wells
EUR 458

Human Interleukin 17, IL-17 ELISA Kit
MBS162336-10x96StripWells 10x96-Strip-Wells
EUR 3460

Human Interleukin 17, IL-17 ELISA Kit
MBS162336-48StripWells 48-Strip-Wells
EUR 285

Human Interleukin 17, IL-17 ELISA Kit
MBS162336-5x96StripWells 5x96-Strip-Wells
EUR 1750

Human Interleukin 17, IL-17 ELISA Kit
MBS162336-96StripWells 96-Strip-Wells
EUR 425

Human IL-17 (Interleukin 17) ELISA Kit
MBS2501369-10x96Tests 10x96Tests
EUR 3265

Human IL-17 (Interleukin 17) ELISA Kit
MBS2501369-24Tests 24Tests
EUR 225

Human IL-17 (Interleukin 17) ELISA Kit
MBS2501369-48Tests 48Tests
EUR 350

Human IL-17 (Interleukin 17) ELISA Kit
MBS2501369-5x96Tests 5x96Tests
EUR 1655

Human IL-17 (Interleukin 17) ELISA Kit
MBS2501369-96Tests 96Tests
EUR 395

Human Interleukin 17 (IL-17) ELISA Kit
MBS261470-10x96StripWells 10x96-Strip-Wells
EUR 3040

Human Interleukin 17 (IL-17) ELISA Kit
MBS261470-48StripWells 48-Strip-Wells
EUR 285

Human Interleukin 17 (IL-17) ELISA Kit
MBS261470-5x96StripWells 5x96-Strip-Wells
EUR 1670

Human Interleukin 17 (IL-17) ELISA Kit
MBS261470-96StripWells 96-Strip-Wells
EUR 405

Human Interleukin 17 (IL-17) ELISA Kit
MBS3800332-10x96StripWells 10x96-Strip-Wells
EUR 6725

Human Interleukin 17 (IL-17) ELISA Kit
MBS3800332-48StripWells 48-Strip-Wells
EUR 550

Human Interleukin 17 (IL-17) ELISA Kit
MBS3800332-5x96StripWells 5x96-Strip-Wells
EUR 3420

Human Interleukin 17 (IL-17) ELISA Kit
MBS3800332-96StripWells 96-Strip-Wells
EUR 765

Human Interleukin 17(IL-17) ELISA Kit    
EIA05898h each
EUR 430

Human Interleukin 17,IL-17 ELISA Kit
201-12-0143 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human Interleukin-17 (IL-17) ELISA Kit
IHUIL17KT each
EUR 702
Description: Human Interleukin-17 (IL-17) ELISA Kit

Human Interleukin-17 (IL-17) ELISA Kit
MBS8413481-1Kit 1Kit
EUR 755

Human Interleukin-17 (IL-17) ELISA Kit
MBS8413481-5x1Kit 5x1Kit
EUR 3455

Human IL-17 /IL-17A ELISA kit
E22-HC170.48 48T
EUR 295

Human IL-17 /IL-17A ELISA kit
E22-HC170.96 96T
EUR 395

Human IL-17/IL-17A ELISA Kit
MBS8579237-48Tests 48Tests
EUR 390

Human IL-17/IL-17A ELISA Kit
MBS8579237-5x96Tests 5x96Tests
EUR 2275

Human IL-17/IL-17A ELISA Kit
MBS8579237-96Tests 96Tests
EUR 495

Recombinant Human Interleukin-17 (rHu IL-17)
MBS9419916-0025mL 0.025mL
EUR 280

Recombinant Human Interleukin-17 (rHu IL-17)
MBS9419916-5x0025mL 5x0.025mL
EUR 1120

IL-17 Interleukin-17 Human Recombinant Protein
PROTQ16552-1 Regular: 25ug
EUR 380.4
Description: Interleukin-17A Human Recombinant produced in E.Coli is a homodimeric, non-glycosylated polypeptide chain containing a total of 264 amino acids (2 chains of 132 aa) and having a molecular mass of 31kDa.  ;The IL-17 is purified by proprietary chromatographic techniques.

Recombinant Human IL-17 (IL-17A) Protein
PROTQ16552-4 25ug
EUR 380.4
Description: The originally described IL-17 protein, now known as IL-17A, is a homodimer of two 136 amino acid chains, secreted by activated T-cells that act on stromal cells to induce production of proinflammatory and hematopoietic bioactive molecules.  Today, IL-17 represents a family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles.  The six known members of this family, IL-17A through IL-17F, are secreted as homodimers.  IL-17A exhibits cross-species bioactivity between human and murine cells.  Recombinant human IL-17A is a 31.3 kDa disulfide-linked homodimer of two 137 amino acid polypeptide chains.

Recombinant Human IL-17/IL-17A Protein
RP00395 10μg
EUR 134.62

Recombinant Human IL-17/IL-17A Protein
RP00821 10μg
EUR 85.02

human IL-17, His tag
E410A10-100 100μg
EUR 700
Description: Inflammation Storm Cytokine

human IL-17, His tag
MBS8574809-01mg 0.1mg
EUR 505

human IL-17, His tag
MBS8574809-5x01mg 5x0.1mg
EUR 2015

Anti-Human IL-17 (IL-17A) Goat Polyclonal Antibody
TA328238 100 µg Ask for price

Anti-Human IL-17 (IL-17A) Rabbit Polyclonal Antibody
TA328239 100 µg Ask for price

Human IL-17 ELISA Kit
E16HE0054 96T
EUR 733.33

Human IL-17 ELISA KIT
E16HE0054-048 48 wells
EUR 295

Human IL-17 ELISA KIT
E16HE0054-096 96 wells
EUR 395

Human IL-17 ELISA KIT
E42EH-11 96T/48T Ask for price

IL-17 (Human) ELISA Kit
E4628-100 each
EUR 874.8

Human IL-17 ELISA KIT
EF006939 96tests
EUR 566

Human IL-17 ELISA Kit
GWB-ZZD054 1x96 well plate Ask for price

Human IL-17 ELISA kit
LF-EK50201 1×96T
EUR 777.6

Human IL-17 ELISA Kit
RK00397 96 Tests
EUR 280

Human IL-17 ELISA KIT
MBS9424822-5x96Tests 5x96Tests
EUR 2225

Human IL-17 ELISA KIT
MBS9424822-96Tests 96Tests
EUR 485

Human IL-17 ELISA Kit
MBS8244675-5x96Tests 5x96Tests
EUR 2755

Human IL-17 ELISA Kit
MBS8244675-96Tests 96Tests
EUR 620

Human IL-17 ELISA Kit
MBS824670-5x96Tests 5x96Tests
EUR 2755

Human IL-17 ELISA Kit
MBS824670-96Tests 96Tests
EUR 620

Human IL-17 ELISA Kit
MBS9135954-5x96Tests 5x96Tests
EUR 2615

Human IL-17 ELISA Kit
MBS9135954-96Tests 96Tests
EUR 570

Human IL-17 ELISA KIT
MBS8506110-48Wells 48Wells
EUR 390

Human IL-17 ELISA KIT
MBS8506110-5x96Wells 5x96Wells
EUR 2275

Human IL-17 ELISA KIT
MBS8506110-96Wells 96Wells
EUR 495

Human IL-17 ELISA Kit
MBS824986-5x96Tests 5x96Tests
EUR 2755

Human IL-17 ELISA Kit
MBS824986-96Tests 96Tests
EUR 620

IL-17 Human ELISA Kit
MBS355268-5x96Tests 5x96Tests
EUR 2190

IL-17 Human ELISA Kit
MBS355268-96Tests 96Tests
EUR 485

Human IL-17 ELISA Kit
MBS9719278-48Tests 48Tests
EUR 300

Human IL-17 ELISA Kit
MBS9719278-5x48Tests 5x48Tests
EUR 1365

Human IL-17 ELISA Kit
MBS9719278-5x96Tests 5x96Tests
EUR 1750

Human IL-17 ELISA Kit
MBS9719278-96Tests 96Tests
EUR 385

Human IL-17 GENLISA ELISA
KBH0142 1 x 96 wells
EUR 286

Recombinant Human IL-17 protein
CD01557-5ug 5ug
EUR 176
Description: Human Interleukin-17A (IL-17A) is encoded by the IL17A gene located on the chromosome 6 and belongs to the IL-17 family that contains IL-17A, IL-17B, IL-17C, IL-17D, IL-17E and IL-17F. They have a similar protein structure, with four highly conserved cysteine residues critical to their 3-dimensional shape, but no sequence similarity to any other known cytokines. Interleukin 17 is a T cell-expressed pleiotropic cytokine that exhibits a high degree of homology to a protein encoded by the ORF13 gene of herpesvirus Saimiri. Mature IL-17 containing one potential N-linked glycosylation site. Both recombinant and natural IL-17 have been shown to exist as disulfide linked homodimers. At the amino acid level, IL-17 exhibits 63 % amino acid identity with mouse IL-17. High levels of human IL-17 were induced from primary peripheral blood CD4+ T cells upon stimulation and they can induce stromal cells to produce proinflammatory and hematopoietic cytokines.

Anti-Mouse IL-17 Antibody
103-M411 100 µg
EUR 399
Description: The IL-17 family is comprised of at least six proinflammatory cytokines that share a conserved cysteine-knot structure but diverge at the N-terminus. IL-17 family members are glycoproteins secreted as dimers that induce local cytokine production and recruit granulocytes to sites of inflammation. IL-17 is induced by IL-15 and IL-23, mainly in activated CD4+ T cells distinct from Th1 or Th2 cells. IL-17F is the most homologous to IL-17, but is induced only by IL-23 in activated monocytes. IL-17B binds the IL-17B receptor, but not the IL-17 receptor; it is most homologous with IL-17D, which is expressed by resting CD4+ T cells and CD19+ B cells. IL-17E is mainly produced by Th2 cells and recruits eosinophils to lung tissue. IL-17C has a very restricted expression pattern but has been detected in adult prostate and fetal kidney libraries.

Anti-IL-17 alpha antibody
STJ93683 200 µl
EUR 236.4
Description: Rabbit polyclonal to IL-17Ralpha.

Rabbit anti-IL-17 Antibody
DL90598A-100ul 100 ul
EUR 299
Description: CTLA8; IL17; Interleukin-17A; IL-17; IL-17A; Cytotoxic T-lymphocyte-associated antigen 8; CTLA-8

Rabbit anti-IL-17 Antibody
DL90598A-50ul 50 ul
EUR 209.3
Description: CTLA8; IL17; Interleukin-17A; IL-17; IL-17A; Cytotoxic T-lymphocyte-associated antigen 8; CTLA-8

Rabbit anti-IL-17 Antibody
YLD4293-100ul 100 ul
EUR 320
Description: Rabbit polyclonal antibody to IL-17

Rabbit anti-IL-17 Antibody
YLD4293-50ul 50 ul
EUR 200
Description: Rabbit polyclonal antibody to IL-17

Anti-Human IL-17 (CTLA-8) Antibody
101-M783 100 µg
EUR 399
Description: The IL-17 family is comprised of at least six proinflammatory cytokines that share a conserved cysteine-knot structure but diverge at the N-terminus. IL-17 family members are glycoproteins secreted as dimers that induce local cytokine production and recruit granulocytes to sites of inflammation. IL-17 is induced by IL-15 and IL-23, mainly in activated CD4+ T cells distinct from Th1 or Th2 cells. IL-17F is the most homologous to IL-17, but is induced only by IL-23 in activated monocytes. IL-17B binds the IL-17B receptor, but not the IL-17 receptor; it is most homologous with IL-17D, which is expressed by resting CD4+ T cells and CD19+ B cells. IL-17E is mainly produced by Th2 cells and recruits eosinophils to lung tissue. IL-17C has a very restricted expression pattern but has been detected in adult prostate and fetal kidney libraries.

CLIA kit for Human IL-17 (Interleukin 17)
E-CL-H0104 1 plate of 96 wells
EUR 700.8
Description: A sandwich CLIA kit for quantitative measurement of Human IL-17 (Interleukin 17) in samples from Serum, Plasma, Cell supernatant

ELISA kit for Human IL-17 (Interleukin 17)
E-EL-H0105 1 plate of 96 wells
EUR 452.4
Description: A sandwich ELISA kit for quantitative measurement of Human IL-17 (Interleukin 17) in samples from Serum, Plasma, Cell supernatant

Human Interleukin 17 (IL-17) Detection Assay Kit
6808 1 kit
EUR 357
Description: Culture Media, Serum, Plasma

IL-17 Interleukin-17 Human Recombinant Protein, HEK
PROTQ16552 Regular: 10ug
EUR 380.4
Description: IL-17 Human Recombinant produced in HEK cells is a glycosylated homodimer, having a molecular weight range of 30-35kDa due to glycosylation.;The IL-17 is purified by proprietary chromatographic techniques.

Biotinylated Anti-Human IL-17 (IL-17A) Goat Polyclonal Antibody
TA328237 50 µg Ask for price

Biotinylated Anti-Human IL-17 (IL-17A) Rabbit Polyclonal Antibody
TA328236 50 µg Ask for price

ELISA kit for Human IL-17
KET6022-48T 48T
EUR 242.4
Description: Quantitative sandwich ELISA for measuring Human IL-17 in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human IL-17
KET6022-5platesof96wells 5 plates of 96 wells
EUR 1292.4
Description: Quantitative sandwich ELISA for measuring Human IL-17 in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human IL-17
KET6022-96T 96T
EUR 346.8
Description: Quantitative sandwich ELISA for measuring Human IL-17 in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Anti‐Human IL‐17A
E2790213 100ul
EUR 225
Description: Available in various conjugation types.

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