A 2020 update on the use of genetic testing for patients

A 2020 update on the use of genetic testing for patients with primary immunodeficiency
- Introduction: Genetic testing of patients with clinically diagnosed or suspected primary immunodeficiencies (PIDs) constitutes standard of care. Choice of testing modality and patient attributes can impact the likelihood of securing a diagnosis.
- Areas covered: Published diagnostic rates for gene panel testing, exome sequencing (WES), and whole genome sequencing are compared among cohorts identified within PubMed. Performance of the testing platforms is reviewed in PIDs taken as a whole, followed by separate cohorts of patients with suspected PIDs, specific PIDs, and clinical phenotypes that can be associated with underlying PIDs.
- Expert opinion: Massively parallel high throughput sequencing clearly represents the most expedient method for diagnosis of PIDs. For patients from highly consanguineous backgrounds, WES and whole genome sequencing should be performed to obtain optimal diagnostic yield. For patients for whom familial consanguinity is unlikely, choice of platform depends upon the phenotype. In patients with suspected PIDs, assessment for copy number variants is important, whether as part of gene panel bioinformatic analyses or combined with WES.
- Diagnostic rates overall for massively parallel sequencing are high for clinically diagnosed and suspected PIDs. WES may have a slightly higher overall yield, but gene panel testing represents a cost effective and efficient reasonable initial step.

![]() |
|||
RK00038 | Abclonal | 96 Tests | EUR 521 |
![]() |
|||
20-abx260684 | Abbexa |
|
|
|
![]() |
|||
20-abx261870 | Abbexa |
|
|
|
![]() |
|||
PROTP12850-1 | BosterBio | Regular: 20ug | EUR 317 |
Description: KC Mouse Recombinant also known as N51 and GRO1 produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 77 amino acids and having a molecular mass of approximately 8 kDa.;The GRO-1 is purified by proprietary chromatographic techniques. |
![]() |
|||
RP-1037 | Alpha Diagnostics | 5 ug | EUR 164 |
![]() |
|||
P1288-25 | Biovision | EUR 370 |
![]() |
|||
P1288-5 | Biovision | EUR 175 |
![]() |
|||
PROTP12850-2 | BosterBio | 20ug | EUR 317 |
Description: All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant murine KC is a 7.8 kDa protein consisting of 72 amino acids including the 'ELR' motif common to the CXC chemokine family that bind to CXCR1 or CXCR2. |
![]() |
|||
RC352-12 | Bio Basic | 5ug | EUR 104.38 |
|
![]() |
|||
PROTP12850 | BosterBio | Regular: 20ug | EUR 317 |
Description: GRO1/KC Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 97 amino acids (25-96 a.a.) and having a molecular mass of 10.5kDa.;GRO1 is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
![]() |
|||
RC332-12 | Bio Basic | 5ug | EUR 104.38 |
|
![]() |
|||
PROTP14095-1 | BosterBio | 25ug | EUR 317 |
Description: All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant rat GRO/KC is a 7.8 kDa protein consisting of 72 amino acids including the 'ELR' motif common to the CXC chemokine family that bind to CXCR1 or CXCR2. |
![]() |
|||
RK00196 | Abclonal | 96 Tests | EUR 521 |
![]() |
|||
30R-AK001 | Fitzgerald | 20 ug | EUR 273 |
Description: Purified recombinant Mouse KC protein |
![]() |
|||
STJ72026 | St John's Laboratory | 100 µg | EUR 260 |
![]() |
|||
STJ28366 | St John's Laboratory | 100 µl | EUR 277 |
Description: This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression of this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4. |
![]() |
|||
Anti-CRBN | ImmunoStep | 50 µg | EUR 349 |
![]() |
|||
CPBT-65100RM | Creative Diagnostics | 0.1 mg | EUR 881 |
![]() |
|||
70R-KR006 | Fitzgerald | 50 ug | EUR 273 |
Description: Affinity purified Rabbit polyclonal KC antibody |
![]() |
|||
5211-100 | Biovision | EUR 376 |
![]() |
|||
5212-100 | Biovision | EUR 392 |
![]() |
|||
5212-30T | Biovision | EUR 146 |
![]() |
|||
20R-1786 | Fitzgerald | 100 ug | EUR 651 |
Description: Rabbit polyclonal KC antibody |
![]() |
|||
70R-12297 | Fitzgerald | 100 ug | EUR 527 |
Description: Rabbit polyclonal KC antibody |
![]() |
|||
70R-12298 | Fitzgerald | 100 ug | EUR 492 |
Description: Rabbit polyclonal KC antibody |
![]() |
|||
LF-MA90006 | Abfrontier | 20 ug | EUR 1025 |
Description: Mouse monoclonal to 7-ketocholesterol (7-KC) |
![]() |
|||
LF-MA90007 | Abfrontier | 100 ug | EUR 2725 |
Description: Mouse monoclonal to 7-ketocholesterol (7-KC) |
![]() |
|||
A00533 | BosterBio | 100ug/vial | EUR 294 |
![]() |
|||
PA1760 | BosterBio | 100ug/vial | EUR 294 |
![]() |
|||
APR16969G | Leading Biology | 0.1mg | EUR 484 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human KC . This antibody is tested and proven to work in the following applications: |
![]() |
|||
B7332-10 | ApexBio | 10 mg | EUR 373 |
![]() |
|||
B7332-50 | ApexBio | 50 mg | EUR 1363 |
![]() |
|||
33R-11041 | Fitzgerald | 50 ug | EUR 191 |
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of KC antibody, catalog no. 70R-12298 |
![]() |
|||
5212BP-50 | Biovision | EUR 153 |
![]() |
|||
HY-P7188 | MedChemExpress | 50ug | EUR 533 |
![]() |
|||
55R-1741 | Fitzgerald | 1 kit | EUR 624 |
Description: ELISA kit for detection of CXCL1 in the research laboratory |
![]() |
|||
20-abx970673 | Abbexa |
|
|
|
![]() |
|||
E03K0088-192T | B-Gene | 192 tests | EUR 1270 |
|
|||
Description: A sandwich ELISA for quantitative measurement of Mouse keinocyte chemoattractant (KC) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
![]() |
|||
E03K0088-48 | B-Gene | 1 plate of 48 wells | EUR 520 |
|
|||
Description: A sandwich ELISA for quantitative measurement of Mouse keinocyte chemoattractant (KC) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
![]() |
|||
E03K0088-96 | B-Gene | 1 plate of 96 wells | EUR 685 |
|
|||
Description: A sandwich ELISA for quantitative measurement of Mouse keinocyte chemoattractant (KC) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
![]() |
|||
20-abx901350 | Abbexa |
|
|
|
![]() |
|||
E21-597 | EnoGene | 10ug | EUR 343 |
![]() |
|||
EF012822 | Lifescience Market | 96 Tests | EUR 689 |
![]() |
|||
20-abx913248 | Abbexa |
|
|
|
![]() |
|||
20-abx913249 | Abbexa |
|
|
|
![]() |
|||
43679-100ul | SAB | 100ul | EUR 252 |
![]() |
|||
30R-3156 | Fitzgerald | 50 ug | EUR 257 |
Description: Purified recombinant CXCL1 protein |
![]() |
|||
33054-100ul | SAB | 100ul | EUR 252 |
![]() |
|||
70R-14297 | Fitzgerald | 100 ug | EUR 327 |
Description: Affinity purified Rabbit polyclonal CXCL1 antibody |
![]() |
|||
70R-10502 | Fitzgerald | 50 ug | EUR 467 |
Description: Affinity purified rabbit polyclonal CXCL1 antibody |
![]() |
|||
70R-15473 | Fitzgerald | 100 ug | EUR 327 |
Description: Rabbit polyclonal CXCL1 antibody |
![]() |
|||
70R-16681 | Fitzgerald | 50 ul | EUR 435 |
Description: Rabbit polyclonal CXCL1 antibody |
![]() |
|||
1-CSB-PA006239GA01HU | Cusabio |
|
|
|
|||
Description: A polyclonal antibody against CXCL1. Recognizes CXCL1 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC |
![]() |
|||
1-CSB-PA009036 | Cusabio |
|
|
|
|||
Description: A polyclonal antibody against CXCL1. Recognizes CXCL1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: IHC, ELISA;IHC:1/100-1/300.ELISA:1/10000 |
![]() |
|||
1-CSB-PA09217A0Rb | Cusabio |
|
|
|
|||
Description: A polyclonal antibody against Cxcl1. Recognizes Cxcl1 from Mouse. This antibody is Unconjugated. Tested in the following application: ELISA |
![]() |
|||
1-CSB-PA06097A0Rb | Cusabio |
|
|
|
|||
Description: A polyclonal antibody against CXCL1. Recognizes CXCL1 from Human. This antibody is Unconjugated. Tested in the following application: ELISA |
![]() |
|||
PVT10178 | Lifescience Market | 2 ug | EUR 301 |
![]() |
|||
CPBT-65101RR | Creative Diagnostics | 0.1 mg | EUR 881 |
![]() |
|||
GST-ANTI-1 | Detroit R&D | 50 uL | EUR 280 |
![]() |
|||
GST-ANTI-2 | Detroit R&D | 50 uL | EUR 280 |
![]() |
|||
GST-ANTI-3 | Detroit R&D | 50 uL | EUR 280 |
![]() |
|||
MasterMix-KC | ABM | 4 x 1.25 ml - 500 reactions (20 ul) | EUR 140 |
![]() |
|||
4210-100 | Biovision | EUR 773 |
![]() |
|||
4210-1000 | Biovision | EUR 3856 |
![]() |
|||
4210-20 | Biovision | EUR 256 |
![]() |
|||
EK5299 | SAB | 96 tests | EUR 553 |
Description: Enzyme-linked immunosorbent assay kit for quantification of Mouse CXCL1 in samples from serum, plasma, tissue homogenates and other biological fluids. |
![]() |
|||
EK0723 | BosterBio | 96 wells | EUR 456 |
Description: For quantitative detection of mouse CXCL1 in cell culture supernates and serum. |
![]() |
|||
80R-3368 | Fitzgerald | 50 ug | EUR 257 |
Description: Purified recombinant CXCL1 protein (Mouse) (His tag) |
![]() |
|||
80R-3439 | Fitzgerald | 50 ug | EUR 257 |
Description: Purified recombinant CXCL1 protein (Mouse) (His tag) |
![]() |
|||
6725 | Chondrex | 1 kit | EUR 483.55 |
Description: Mouse CXCL1 Detection Assay Kit |
![]() |
|||
LF-EK50473 | Abfrontier | 1×96T | EUR 648 |
![]() |
|||
ORF042286 | ABM | 1.0 ug DNA | EUR 95 |
![]() |
|||
OKAN04583 | Aviva Systems Biology | 96 Wells | EUR 792 |
Description: Description of target: This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This secretory protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils. In mouse, deficiency of this gene is associated with colitis and with defects in immune cell recruitment to the lung.;Species reactivity: Mouse;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 6.0 pg/mL |
![]() |
|||
OKBB00312 | Aviva Systems Biology | 96 Tests | EUR 544 |
Description: Description of target: Chemokine (C-X-C motif) ligand 1 (CXCL1) is a small cytokine belonging to the CXC chemokine family that was previously called GRO1 oncogene, GROα, KC, Neutrophil-activating protein 3 (NAP-3) and melanoma growth stimulating activity, alpha (MSGA-α). In humans, this protein is encoded by the CXCL1 gene. The gene for CXCL1 is located on human chromosome 4 amongst genes for other CXC chemokines. The mature form of CXCL1 is maximally 73 amino acids long. CXCL1 is secreted by human melanoma cells, has mitogenic properties and is implicated in melanoma pathogenesis. CXCL1 is expressed by macrophages, neutrophils and epithelial cells, and has neutrophil chemoattractant activity. This chemokine elicits its effects by signaling through the chemokine receptor CXCR2.CXCL1 decreased the severity of multiple sclerosis and may offer a neuro-protective function. The standard product used in this kit is recombinant mouse CXCL1, consisting of 77 amino acids with the molecular mass of 8KDa.;Species reactivity: Mouse;Application: ELISA;Assay info: ;Sensitivity: < 1 pg/ml |
![]() |
|||
OKCD05712 | Aviva Systems Biology | 96 Wells | EUR 609 |
Description: Description of target: This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This secretory protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils. In mouse, deficiency of this gene is associated with colitis and with defects in immune cell recruitment to the lung.;Species reactivity: Mouse;Application: ELISA;Assay info: ;Sensitivity: < 6.0pg/mL |
![]() |
|||
OKAG00090 | Aviva Systems Biology | 96 Wells | EUR 596 |
Description: Description of target: This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This secretory protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils. In mouse, deficiency of this gene is associated with colitis and with defects in immune cell recruitment to the lung.;Species reactivity: Mouse;Application: ELISA;Assay info: Quantitative Colorimentric Sandwich ELISA;Sensitivity: 8 pg/mL |
![]() |
|||
C33054 | SAB | 100ul | EUR 397 |
![]() |
|||
CSB-CL006239HU-10ug | Cusabio | 10ug | EUR 233 |
|
|||
Description: A cloning plasmid for the CXCL1 gene. |
![]() |
|||
20-abx061039 | Abbexa |
|
|
|
![]() |
|||
A51950 | EpiGentek | 100 µg | EUR 570.55 |
Description: fast delivery possible |
![]() |
|||
A51978 | EpiGentek | 100 µg | EUR 570.55 |
Description: kits suitable for this type of research |
![]() |
|||
33R-7741 | Fitzgerald | 100 ug | EUR 180 |
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of CXCL1 antibody, catalog no. 70R-10502 |
![]() |
|||
60R-2236 | Fitzgerald | 100 ug | EUR 327 |
Description: Rabbit polyclonal CXCL1 antibody (HRP) |
![]() |
|||
60R-2237 | Fitzgerald | 100 ug | EUR 327 |
Description: Rabbit polyclonal CXCL1 antibody (FITC) |
![]() |
|||
60R-2238 | Fitzgerald | 100 ug | EUR 327 |
Description: Rabbit polyclonal CXCL1 antibody (biotin) |
![]() |
|||
P0109 | FN Test | 100ug | EUR 522.36 |
|
|||
Description: Recombinant Human protein for CXCL1 |
![]() |
|||
PVT13291 | Lifescience Market | 2 ug | EUR 391 |
![]() |
|||
HY-P7186 | MedChemExpress | 50ug | EUR 337 |
![]() |
|||
70027-05141 | AssayPro | 150 ug | EUR 428 |
![]() |
|||
K4368201 | ABM | 3 x 1.0 ug | EUR 339 |
![]() |
|||
1-CSB-RP092174m | Cusabio |
|
|
|
|||
Description: Recombinant Mouse Growth-regulated alpha protein(Cxcl1),partial expressed in E.coli |
![]() |
|||
LF-EK50474 | Abfrontier | 4×96T | EUR 2201 |
![]() |
|||
20-abx986581 | Abbexa |
|
|
|
![]() |
|||
ELA-E1210h | Lifescience Market | 96 Tests | EUR 824 |
![]() |
|||
EF003720 | Lifescience Market | 96 Tests | EUR 689 |
![]() |
|||
HY-P7187 | MedChemExpress | 10ug | EUR 268 |
Breast cancer (BRCA) genetesting in ovarian cancer
The discovery of cancer-causing BRCA1/2 mutations and the emergence of genetic testing have brought precision in patient selection for poly-(ADP)-ribose polymerase inhibitor (PARPi) treatment. Interestingly, patients who are carriers of BRCA1/2 mutations have a higher risk for developing cancer, but respond better to DNA-damaging cytotoxic therapy, such as platinum-based chemotherapy.
The distinctive biology of ovarian cancer involves high genomic instability consisting of gene amplification, gene deletion, oncogene hypomethylation, loss of heterozygosity, and tumor suppressor gene promoter hypermethylation in many of the DNA damage response (DDR) genes, including BRCA1/2. Several of these genetic abnormalities can impair high fidelity DNA damage repair increasing the therapeutic audience for PARPi’s. This is especially important given the clinical development over the last decade of this group of agents and the dramatic increase in progression free survival among ovarian cancer patients who received PARPi, both in treatment or maintenance setting. In this review, we summarize our current understanding of the role of BRCA1/2 mutations in ovarian cancer and present relevant clinical trials in which BRCA1/2 was investigated as biomarker for therapy. We also outline the role of homologous recombination (HR) deficiency as biomarker by presenting the recent clinical development and recent approvals PARPi for firstline maintenance in ovarian cancer.
Haplotyping by linked-read sequencing (HLRS) of the genetic disease carriers for preimplantation genetictesting without a proband or relatives
Background: In order to mitigate the risk of allele dropout (ADO) and ensure the accuracy of preimplantation genetic testing for monogenic disease (PGT-M), it is necessary to construct parental haplotypes. Typically, haplotype resolution is obtained by genotyping multiple polymorphic markers in both parents and a proband or a relative. Sometimes, single sperm typing, or tests on the polar bodies may also be useful. Nevertheless, this process is time-consuming. At present, there was no simple linkage analysis strategy for patients without affected relatives.
Method: To solve this problem, we established a haplotyping by linked-read sequencing (HLRS) method without the requirement for additional relatives. First, the haplotype of the genetic disease carriers in the family was constructed by linked-read sequencing, and then the informative single nucleotide polymorphisms (SNPs) in upstream and downstream mutation region were selected to construct the embryo haplotype and to determine whether the embryo was carrying the mutation. Two families were selected to validate this method; one with alpha thalassemia and the other with NDP gene disorder.
Results: The haplotyping by linked-read sequencing (HLRS) method was successfully applied to construct parental haplotypes without recruiting additional family members; the method was also validated for PGT-M. The mutation carriers in these families were sequenced by linked-read sequencing, and their haplotypes were successfully phased. Adjacent SNPs of the mutation gene were identified.
The informative SNPs were chosen for linkage analyses to identify the carrier embryos. For the alpha thalassemia family, a normal blastocyst was transferred to the uterus and the accuracy of PGT-M was confirmed by amniocentesis at 16 weeks of gestation.
Conclusions: Our results suggest that HLRS can be applied for PGT-M of monogenic disorders or de novo mutations where the mutations haplotype cannot be determined due to absence of affected relatives.
![]() Human Cluster Of Differentiation (CD163) ELISA Kit |
|||
RDR-CD163-Hu-48Tests | Reddot Biotech | 48 Tests | EUR 522 |
![]() Human Cluster Of Differentiation (CD163) ELISA Kit |
|||
RDR-CD163-Hu-96Tests | Reddot Biotech | 96 Tests | EUR 724 |
![]() Anti-CD163 |
|||
DB-045-0.1 | DB Biotech | 100 μl | EUR 212 |
Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated |
![]() Anti-CD163 |
|||
DB-045-0.2 | DB Biotech | 200 μl | EUR 298 |
Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated |
![]() Anti-CD163 |
|||
DB-045-0.5 | DB Biotech | 500 μl | EUR 384 |
Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated |
![]() Anti-CD163 |
|||
DB-045-1 | DB Biotech | 1 ml | EUR 613 |
Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated |
![]() Anti-CD163 |
|||
DB-045-RTU-15 | DB Biotech | 15 ml | EUR 354 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
![]() Anti-CD163 |
|||
DB-045-RTU-7 | DB Biotech | 7 ml | EUR 231 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
![]() Anti-CD163 |
|||
DB045RTU-15 | DB Biotech | 15 ml | EUR 354 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
![]() Anti-CD163 |
|||
DB045RTU-7 | DB Biotech | 7 ml | EUR 231 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
![]() Mouse Cluster Of Differentiation (CD163) ELISA Kit |
|||
DLR-CD163-Mu-48T | DL Develop | 48T | EUR 508 |
|
|||
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Cluster Of Differentiation (CD163) in samples from serum, plasma or other biological fluids. |
![]() Mouse Cluster Of Differentiation (CD163) ELISA Kit |
|||
DLR-CD163-Mu-96T | DL Develop | 96T | EUR 661 |
|
|||
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Cluster Of Differentiation (CD163) in samples from serum, plasma or other biological fluids. |
![]() Rat Cluster Of Differentiation (CD163) ELISA Kit |
|||
DLR-CD163-Ra-48T | DL Develop | 48T | EUR 508 |
|
|||
Description: A sandwich quantitative ELISA assay kit for detection of Rat Cluster Of Differentiation (CD163) in samples from serum, plasma, tissue homogenates or other biological fluids. |
![]() Rat Cluster Of Differentiation (CD163) ELISA Kit |
|||
DLR-CD163-Ra-96T | DL Develop | 96T | EUR 661 |
|
|||
Description: A sandwich quantitative ELISA assay kit for detection of Rat Cluster Of Differentiation (CD163) in samples from serum, plasma, tissue homogenates or other biological fluids. |
![]() Mouse Cluster Of Differentiation (CD163) ELISA Kit |
|||
RD-CD163-Mu-48Tests | Reddot Biotech | 48 Tests | EUR 511 |
![]() Mouse Cluster Of Differentiation (CD163) ELISA Kit |
|||
RD-CD163-Mu-96Tests | Reddot Biotech | 96 Tests | EUR 709 |
![]() Rat Cluster Of Differentiation (CD163) ELISA Kit |
|||
RD-CD163-Ra-48Tests | Reddot Biotech | 48 Tests | EUR 511 |
![]() Rat Cluster Of Differentiation (CD163) ELISA Kit |
|||
RD-CD163-Ra-96Tests | Reddot Biotech | 96 Tests | EUR 709 |
![]() Mouse Cluster Of Differentiation (CD163) ELISA Kit |
|||
RDR-CD163-Mu-48Tests | Reddot Biotech | 48 Tests | EUR 534 |
![]() Mouse Cluster Of Differentiation (CD163) ELISA Kit |
|||
RDR-CD163-Mu-96Tests | Reddot Biotech | 96 Tests | EUR 742 |
![]() Rat Cluster Of Differentiation (CD163) ELISA Kit |
|||
RDR-CD163-Ra-48Tests | Reddot Biotech | 48 Tests | EUR 534 |
![]() Rat Cluster Of Differentiation (CD163) ELISA Kit |
|||
RDR-CD163-Ra-96Tests | Reddot Biotech | 96 Tests | EUR 742 |
![]() Anti-CD163 Antibody |
|||
A00812-1 | BosterBio | 100ug/vial | EUR 334 |
![]() Anti-CD163 Antibody |
|||
PA1874 | BosterBio | 100ug/vial | EUR 294 |
![]() Anti-CD163 Antibody |
|||
PA1874-1 | BosterBio | 100ug/vial | EUR 334 |
![]() Anti-CD163 Antibody |
|||
STJ500423 | St John's Laboratory | 100 µg | EUR 476 |
![]() Anti-CD163 Antibody |
|||
STJ500424 | St John's Laboratory | 100 µg | EUR 476 |
![]() Anti-CD163 antibody |
|||
STJ110681 | St John's Laboratory | 100 µl | EUR 277 |
Description: The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
![]() Anti-CD163 antibody |
|||
STJ160082 | St John's Laboratory | 1 mL C | EUR 941 |
![]() Anti-CD163 antibody |
|||
STJ16100302 | St John's Laboratory | 100 µg | EUR 720 |
![]() Anti-CD163 antibody |
|||
STJ16100324 | St John's Laboratory | 1 mL | EUR 979 |
![]() Anti-CD163 antibody |
|||
STJ180301 | St John's Laboratory | 0.1 ml | EUR 215 |
![]() Anti-CD163 antibody |
|||
STJ190009 | St John's Laboratory | 200 µl | EUR 197 |
Description: Unconjugated Mouse monoclonal to CD163 (AS1A1) |
![]() Rabbit Polyclonal antibody Anti-CRBN |
|||
Anti-CRBN | ImmunoStep | 50 µg | EUR 349 |
![]() anti- CD163/M130 Antibody |
|||
FNab09771 | FN Test | 100µg | EUR 548.75 |
|
|||
Description: Antibody raised against CD163/M130 |
![]() Anti-CD163/M130 Antibody |
|||
A00812 | BosterBio | 100ul | EUR 397 |
Description: Rabbit IgG polyclonal antibody for Scavenger receptor cysteine-rich type 1 protein M130 (CD163) detection.tested for IF, IHC, WB in Human, Mouse, Rat. Various direct flourescent conjugates are available for FCM upon request. Please contact us for details. |
![]() Anti-Hu CD163 Purified |
|||
11-645-C025 | ExBio | 0.025 mg | EUR 99 |
![]() Anti-Hu CD163 Purified |
|||
11-645-C100 | ExBio | 0.1 mg | EUR 158 |
![]() Anti-Hu CD163 APC |
|||
1A-645-T025 | ExBio | 25 tests | EUR 140 |
![]() Anti-Hu CD163 APC |
|||
1A-645-T100 | ExBio | 100 tests | EUR 240 |
![]() Anti-Hu CD163 PE |
|||
1P-645-T025 | ExBio | 25 tests | EUR 140 |
![]() Anti-Hu CD163 PE |
|||
1P-645-T100 | ExBio | 100 tests | EUR 240 |
![]() Anti-CD163/M130 antibody |
|||
PAab09771 | Lifescience Market | 100 ug | EUR 355 |
![]() Anti-CD163 Antibody BIOTIN |
|||
STJ500425 | St John's Laboratory | 100 µg | EUR 586 |
![]() Anti-CD163 Antibody FITC |
|||
STJ500426 | St John's Laboratory | 100 µg | EUR 586 |
![]() Anti-CD163 Antibody BIOTIN |
|||
STJ500427 | St John's Laboratory | 100 µg | EUR 586 |
![]() Anti-CD163 Antibody FITC |
|||
STJ500428 | St John's Laboratory | 100 µg | EUR 586 |
![]() Human CD163 antigen(CD163)ISA kit |
|||
GA-E0263HM-48T | GenAsia Biotech | 48T | EUR 289 |
![]() Human CD163 antigen(CD163)ISA kit |
|||
GA-E0263HM-96T | GenAsia Biotech | 96T | EUR 466 |
![]() human CD163 antigen,CD163 LISA kit |
|||
201-12-0247 | SunredBio | 96 tests | EUR 440 |
|
|||
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids. |
![]() Human CD163 antigen(CD163)ISA kit |
|||
QY-E05066 | Qayee Biotechnology | 96T | EUR 361 |
![]() Mouse Anti Human Cd163 Monoclonal Antibody |
|||
CABT-47162MH | Creative Diagnostics | 25 µg | EUR 372 |
![]() Mouse Anti Human Cd163 Monoclonal Antibody |
|||
CABT-47163MH | Creative Diagnostics | 0.2 mg | EUR 881 |
![]() Anti-CD163 Rabbit Monoclonal Antibody |
|||
M00812 | BosterBio | 100ug/vial | EUR 397 |
Description: Rabbit Monoclonal CD163 Antibody. Validated in IP, WB and tested in Human. |
![]() Anti-Hu CD163 PE-Cy7 |
|||
T7-645-T025 | ExBio | 25 tests | EUR 154 |
![]() Anti-Hu CD163 PE-Cy7 |
|||
T7-645-T100 | ExBio | 100 tests | EUR 268 |
![]() Anti-Hu CD163 PerCP-Cy5.5 |
|||
T9-645-T025 | ExBio | 25 tests | EUR 196 |
![]() Anti-Hu CD163 PerCP-Cy5.5 |
|||
T9-645-T100 | ExBio | 100 tests | EUR 352 |
![]() Polyclonal Goat anti-GST α-form |
|||
GST-ANTI-1 | Detroit R&D | 50 uL | EUR 280 |
![]() Polyclonal Goat anti-GST μ-form |
|||
GST-ANTI-2 | Detroit R&D | 50 uL | EUR 280 |
![]() Polyclonal Goat anti-GST p-form |
|||
GST-ANTI-3 | Detroit R&D | 50 uL | EUR 280 |
![]() Porcine CD163 antigen,CD163 LISA kit |
|||
GA-E0045PC-48T | GenAsia Biotech | 48T | EUR 364 |
![]() Porcine CD163 antigen,CD163 LISA kit |
|||
GA-E0045PC-96T | GenAsia Biotech | 96T | EUR 590 |
![]() Canine CD163 antigen(CD163 LISA kit |
|||
GA-E0062CN-48T | GenAsia Biotech | 48T | EUR 402 |
![]() Canine CD163 antigen(CD163 LISA kit |
|||
GA-E0062CN-96T | GenAsia Biotech | 96T | EUR 684 |
![]() Mouse Anti Rat Cd163 Monoclonal Antibody |
|||
DMABT-47170MR | Creative Diagnostics | 0.25 mg | EUR 741 |
![]() Mouse Anti Rat Cd163 Monoclonal Antibody |
|||
DMABT-47171MR | Creative Diagnostics | 0.1 mg | EUR 559 |
![]() CD163 siRNA |
|||
20-abx910930 | Abbexa |
|
|
|
![]() CD163 siRNA |
|||
20-abx910931 | Abbexa |
|
|
|
![]() CD163 Antibody |
|||
20-abx242956 | Abbexa |
|
|
|
![]() CD163 Antibody |
|||
ABD8235 | Lifescience Market | 100 ug | EUR 438 |
![]() CD163 Antibody |
|||
37157-100ul | SAB | 100ul | EUR 252 |
![]() CD163 Antibody |
|||
49553-100ul | SAB | 100ul | EUR 333 |
![]() CD163 Antibody |
|||
49553-50ul | SAB | 50ul | EUR 239 |
![]() CD163 antibody |
|||
10R-6496 | Fitzgerald | 100 ug | EUR 203 |
Description: Mouse monoclonal CD163 antibody |
![]() CD163 antibody |
|||
10R-CD163aRT | Fitzgerald | 250 ug | EUR 716 |
Description: Mouse monoclonal CD163 antibody |
![]() CD163 Antibody |
|||
DF8235 | Affbiotech | 200ul | EUR 304 |
Description: CD163 Antibody detects endogenous levels of total CD163. |
![]() CD163 Antibody |
|||
1-CSB-PA969205 | Cusabio |
|
|
|
|||
Description: A polyclonal antibody against CD163. Recognizes CD163 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:1000-1:2000, IHC:1:25-1:100 |
![]() CD163 Antibody |
|||
1-CSB-PA801238LA01HU | Cusabio |
|
|
|
|||
Description: A polyclonal antibody against CD163. Recognizes CD163 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IF; Recommended dilution: IF:1:50-1:200 |
![]() Cd163 Antibody |
|||
1-CSB-PA650452LA01MO | Cusabio |
|
|
|
|||
Description: A polyclonal antibody against Cd163. Recognizes Cd163 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB; Recommended dilution: WB:1:500-1:2000 |
![]() Mouse Anti-Human CD163 monoclonal antibody, clone JID274 |
|||
CABT-L2938-100uL500uL | Creative Diagnostics | 100 uL, 500 uL | EUR 502 |
![]() Anti-Human CD163 DyLight® 488 conjugated Antibody |
|||
A00812-Dyl488 | BosterBio | 100ug/vial | EUR 344 |
![]() Anti-Human CD163 DyLight® 550 conjugated Antibody |
|||
A00812-Dyl550 | BosterBio | 100ug/vial | EUR 344 |
![]() Human CD163 ELISA Kit |
|||
ELA-E1726h | Lifescience Market | 96 Tests | EUR 824 |
![]() Human CD163 shRNA Plasmid |
|||
20-abx956176 | Abbexa |
|
|
|
![]() Human CD163 ELISA Kit |
|||
LF-EK50890 | Abfrontier | 1×96T | EUR 648 |
![]() Human CellExp? CD163, Human recombinant |
|||
9226-10 | Biovision | EUR 305 |
![]() Human CellExp? CD163, Human recombinant |
|||
9226-50 | Biovision | EUR 773 |
![]() Mouse Anti Pig Cd163 Monoclonal Antibody,FITC |
|||
CABT-47164MP | Creative Diagnostics | 0.1 mg | EUR 881 |
![]() Mouse Anti Pig Cd163 Monoclonal Antibody,RPE |
|||
CABT-47166MP | Creative Diagnostics | 100 TEST | EUR 715 |
![]() Mouse Anti Rat Cd163 Monoclonal Antibody,Biotin |
|||
DMABT-47168MR | Creative Diagnostics | 0.1 mg | EUR 881 |
![]() Mouse Anti Rat Cd163 Monoclonal Antibody,FITC |
|||
DMABT-47169MR | Creative Diagnostics | 0.1 mg | EUR 881 |
![]() Mouse Anti Rat Cd163 Monoclonal Antibody,RPE |
|||
DMABT-47172MR | Creative Diagnostics | 100 TEST | EUR 892 |
![]() Anti-CD163 Rabbit Monoclonal Antibody, Clone#RM371 |
|||
M00812-1 | BosterBio | 100uL | EUR 385 |
Description: Anti-CD163 Rabbit Monoclonal Antibody, Clone#RM371 tested in WB, IHC, reactive to Human |
![]() CD163 Conjugated Antibody |
|||
C37157 | SAB | 100ul | EUR 397 |
![]() CD163 Conjugated Antibody |
|||
C49553 | SAB | 100ul | EUR 397 |
![]() Porcine CD163 Protein |
|||
20-abx260472 | Abbexa |
|
|
|
![]() Cd163 Polyclonal Antibody |
|||
A53832 | EpiGentek | 100 µg | EUR 570.55 |
Description: Ask the seller for details |
![]() CD163 Rabbit pAb |
|||
A8383-100ul | Abclonal | 100 ul | EUR 308 |
![]() CD163 Rabbit pAb |
|||
A8383-200ul | Abclonal | 200 ul | EUR 459 |
![]() CD163 Rabbit pAb |
|||
A8383-20ul | Abclonal | 20 ul | EUR 183 |
![]() CD163 Rabbit pAb |
|||
A8383-50ul | Abclonal | 50 ul | EUR 223 |
![]() CD163 antibody (PE) |
|||
61R-1319 | Fitzgerald | 100 tests | EUR 403 |
Description: Mouse monoclonal CD163 antibody (PE) |
![]() CD163 antibody (biotin) |
|||
61R-1569 | Fitzgerald | 100 ug | EUR 349 |
Description: Mouse monoclonal CD163 antibody (biotin) |
![]() CD163 antibody (biotin) |
|||
61R-CD163BHUBT | Fitzgerald | 100 ug | EUR 921 |
Description: Mouse monoclonal CD163 antibody (biotin) |
![]() CD163 antibody (biotin) |
|||
61R-CD163CHUBT | Fitzgerald | 250 ug | EUR 781 |
Description: Mouse monoclonal CD163 antibody (biotin) |
![]() Recombinant Porcine CD163 |
|||
7-04750 | CHI Scientific | 10µg | Ask for price |
![]() Recombinant Porcine CD163 |
|||
7-04751 | CHI Scientific | 50µg | Ask for price |
![]() Recombinant Porcine CD163 |
|||
7-04752 | CHI Scientific | 1mg | Ask for price |
![]() CD163 Blocking Peptide |
|||
DF8235-BP | Affbiotech | 1mg | EUR 195 |
![]() ELISA kit for Human CD163 |
|||
EK5296 | SAB | 96 tests | EUR 553 |
Description: Enzyme-linked immunosorbent assay kit for quantification of Human CD163 in samples from serum, plasma, tissue homogenates and other biological fluids. |
![]() Human CD163 PicoKine ELISA Kit |
|||
EK0715 | BosterBio | 96 wells | EUR 425 |
Description: For quantitative detection of human CD163 in cell culture supernates, serum and plasma(heparin). |
![]() QuickDetect? CD163 (Human) ELISA Kit |
|||
K4422-100 | Biovision | EUR 805 |
![]() CD163 ORF Vector (Human) (pORF) |
|||
ORF017045 | ABM | 1.0 ug DNA | EUR 405 |
![]() CD163 ELISA Kit (Human) (OKAN04666) |
|||
OKAN04666 | Aviva Systems Biology | 96 Wells | EUR 792 |
Description: Description of target: The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.273 ng/mL |
![]() CD163 ELISA Kit (Human) (OKCD07621) |
|||
OKCD07621 | Aviva Systems Biology | 96 Wells | EUR 936 |
Description: Description of target: The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: < 0.273ng/mL |
![]() CD163 ELISA Kit (Human) (OKBB00786) |
|||
OKBB00786 | Aviva Systems Biology | 96 Wells | EUR 505 |
Description: Description of target: CD163(Cluster of Differentiation 163) is a human protein encoded by the CD163 gene. It has also been shown to mark cells of monocyte/macrophage lineage. CD163, a member of the scavenger receptor cysteine-rich(SRCR) superfamily, is exclusively expressed by monocytes and macrophages. Using FISH, somatic cell hybrid analysis, and radiation hybrid analysis, CD163 gene was mapped the to chromosome 12p13.3. CD163 is upregulated in a large range of diseases inflammatory diseases including type 2 diabetes, macrophage activation sickness, Tangier's disease, reumatoid arthritis etc.;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: <150pg/ml |
![]() CD163 ELISA Kit (Human) (OKBB01513) |
|||
OKBB01513 | Aviva Systems Biology | 96 Wells | EUR 570 |
Description: Description of target: CD163(Cluster of Differentiation 163) is a human protein encoded by the CD163 gene. It has also been shown to mark cells of monocyte/macrophage lineage. CD163, a member of the scavenger receptor cysteine-rich(SRCR) superfamily, is exclusively expressed by monocytes and macrophages. Using FISH, somatic cell hybrid analysis, and radiation hybrid analysis, CD163 gene was mapped the to chromosome 12p13.3. CD163 is upregulated in a large range of diseases inflammatory diseases including type 2 diabetes, macrophage activation sickness, Tangier's disease, reumatoid arthritis etc.;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: <150pg/ml |
![]() CD163 sgRNA CRISPR Lentivector set (Human) |
|||
K0405601 | ABM | 3 x 1.0 ug | EUR 339 |
![]() Human soluble CD163(sCD163) ELISA Kit |
|||
CSB-E14050h-24T | Cusabio | 1 plate of 24 wells | EUR 165 |
|
|||
Description: Quantitativesandwich ELISA kit for measuring Human soluble CD163 (sCD163) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price. |
![]() Human soluble CD163(sCD163) ELISA Kit |
|||
1-CSB-E14050h | Cusabio |
|
|
|
|||
Description: Quantitativesandwich ELISA kit for measuring Human soluble CD163(sCD163) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits. |
![]() CD163(M130/1240) Antibody |
|||
BNC551240-100 | Biotium | 100uL | EUR 199 |
Description: Primary antibody against CD163(M130/1240), CF555 conjugate, Concentration: 0.1mg/mL |
![]() CD163(M130/1240) Antibody |
|||
BNC551240-500 | Biotium | 500uL | EUR 544 |
Description: Primary antibody against CD163(M130/1240), CF555 conjugate, Concentration: 0.1mg/mL |
![]() CD163(M130/1240) Antibody |
|||
BNC611240-100 | Biotium | 100uL | EUR 199 |
Description: Primary antibody against CD163(M130/1240), CF660R conjugate, Concentration: 0.1mg/mL |
![]() CD163(M130/1240) Antibody |
|||
BNC611240-500 | Biotium | 500uL | EUR 544 |
Description: Primary antibody against CD163(M130/1240), CF660R conjugate, Concentration: 0.1mg/mL |
![]() CD163(M130/1240) Antibody |
|||
BNC401240-100 | Biotium | 100uL | EUR 199 |
Description: Primary antibody against CD163(M130/1240), CF640R conjugate, Concentration: 0.1mg/mL |
![]() CD163(M130/1240) Antibody |
|||
BNC401240-500 | Biotium | 500uL | EUR 544 |
Description: Primary antibody against CD163(M130/1240), CF640R conjugate, Concentration: 0.1mg/mL |
![]() CD163(M130/1240) Antibody |
|||
BNC431240-100 | Biotium | 100uL | EUR 199 |
Description: Primary antibody against CD163(M130/1240), CF543 conjugate, Concentration: 0.1mg/mL |
![]() CD163(M130/1240) Antibody |
|||
BNC431240-500 | Biotium | 500uL | EUR 544 |
Description: Primary antibody against CD163(M130/1240), CF543 conjugate, Concentration: 0.1mg/mL |
![]() CD163(M130/1240) Antibody |
|||
BNC471240-100 | Biotium | 100uL | EUR 199 |
Description: Primary antibody against CD163(M130/1240), CF647 conjugate, Concentration: 0.1mg/mL |
![]() CD163(M130/1240) Antibody |
|||
BNC471240-500 | Biotium | 500uL | EUR 544 |
Description: Primary antibody against CD163(M130/1240), CF647 conjugate, Concentration: 0.1mg/mL |
![]() CD163(M130/1240) Antibody |
|||
BNC051240-100 | Biotium | 100uL | EUR 199 |
Description: Primary antibody against CD163(M130/1240), CF405M conjugate, Concentration: 0.1mg/mL |
![]() CD163(M130/1240) Antibody |
|||
BNC051240-500 | Biotium | 500uL | EUR 544 |
Description: Primary antibody against CD163(M130/1240), CF405M conjugate, Concentration: 0.1mg/mL |
![]() CD163(M130/1240) Antibody |
|||
BNC041240-100 | Biotium | 100uL | EUR 199 |
Description: Primary antibody against CD163(M130/1240), CF405S conjugate, Concentration: 0.1mg/mL |
![]() CD163(M130/1240) Antibody |
|||
BNC041240-500 | Biotium | 500uL | EUR 544 |
Description: Primary antibody against CD163(M130/1240), CF405S conjugate, Concentration: 0.1mg/mL |
![]() CD163(M130/1240) Antibody |
|||
BNUB1240-100 | Biotium | 100uL | EUR 209 |
Description: Primary antibody against CD163(M130/1240), Concentration: 0.2mg/mL |
![]() CD163(M130/1240) Antibody |
|||
BNUB1240-500 | Biotium | 500uL | EUR 458 |
Description: Primary antibody against CD163(M130/1240), Concentration: 0.2mg/mL |
![]() CD163(M130/1240) Antibody |
|||
BNUM1240-50 | Biotium | 50uL | EUR 395 |
Description: Primary antibody against CD163(M130/1240), 1mg/mL |
![]() Mouse CD163 shRNA Plasmid |
|||
20-abx979200 | Abbexa |
|
|
|
![]() CD163(M130/1240) Antibody |
|||
BNC681240-100 | Biotium | 100uL | EUR 199 |
Description: Primary antibody against CD163(M130/1240), CF568 conjugate, Concentration: 0.1mg/mL |
![]() CD163(M130/1240) Antibody |
|||
BNC681240-500 | Biotium | 500uL | EUR 544 |
Description: Primary antibody against CD163(M130/1240), CF568 conjugate, Concentration: 0.1mg/mL |
![]() CD163(M130/1240) Antibody |
|||
BNC701240-100 | Biotium | 100uL | EUR 199 |
Description: Primary antibody against CD163(M130/1240), CF770 conjugate, Concentration: 0.1mg/mL |