A 2020 update on the use of genetic testing for patients

Ivan September 9, 2020 0 Comments
myasthenickids

A 2020 update on the use of genetic testing for patients with primary immunodeficiency

  • Introduction: Genetic testing of patients with clinically diagnosed or suspected primary immunodeficiencies (PIDs) constitutes standard of care. Choice of testing modality and patient attributes can impact the likelihood of securing a diagnosis.
  • Areas covered: Published diagnostic rates for gene panel testing, exome sequencing (WES), and whole genome sequencing are compared among cohorts identified within PubMed. Performance of the testing platforms is reviewed in PIDs taken as a whole, followed by separate cohorts of patients with suspected PIDs, specific PIDs, and clinical phenotypes that can be associated with underlying PIDs.
  • Expert opinion: Massively parallel high throughput sequencing clearly represents the most expedient method for diagnosis of PIDs. For patients from highly consanguineous backgrounds, WES and whole genome sequencing should be performed to obtain optimal diagnostic yield. For patients for whom familial consanguinity is unlikely, choice of platform depends upon the phenotype. In patients with suspected PIDs, assessment for copy number variants is important, whether as part of gene panel bioinformatic analyses or combined with WES.
  • Diagnostic rates overall for massively parallel sequencing are high for clinically diagnosed and suspected PIDs. WES may have a slightly higher overall yield, but gene panel testing represents a cost effective and efficient reasonable initial step.
myasthenickids
myasthenickids

GRO1/KC Mouse Recombinant Protein (CXCL1)
PROTP12850-1 Regular: 20ug
EUR 317
Description: KC Mouse Recombinant also known as N51 and GRO1 produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 77 amino acids and having a molecular mass of approximately 8 kDa.;The GRO-1 is purified by proprietary chromatographic techniques.

Recombinant Mouse (E.Coli) GRO/KC (CXCL1)
RP-1037 5 ug
EUR 164

GRO/KC (CXCL1), Rat Recombinant
P1288-25
EUR 370

GRO/KC (CXCL1), Rat Recombinant
P1288-5
EUR 175

Recombinant Murine KC (CXCL1) Protein
PROTP12850-2 20ug
EUR 317
Description: All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant murine KC is a 7.8 kDa protein consisting of 72 amino acids including the 'ELR' motif common to the CXC chemokine family that bind to CXCR1 or CXCR2.

GRO, KC, CXCL1, rRtGRO, rat
RC352-12 5ug
EUR 104.38

GRO1/KC Mouse, GRO/KC (CXCL1) Mouse Recombinant Protein, His Tag
PROTP12850 Regular: 20ug
EUR 317
Description: GRO1/KC Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 97 amino acids (25-96 a.a.) and having a molecular mass of 10.5kDa.;GRO1 is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

GRO-alpha, KC, CXCL1 (rMuKC), murine (mouse)
RC332-12 5ug
EUR 104.38

Recombinant Rat GRO/KC (CXCL1) Protein
PROTP14095-1 25ug
EUR 317
Description: All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant rat GRO/KC is a 7.8 kDa protein consisting of 72 amino acids including the 'ELR' motif common to the CXC chemokine family that bind to CXCR1 or CXCR2.

Rat CXCL1/CINC-1/KC ELISA Kit
RK00196 96 Tests
EUR 521

KC protein (Mouse)
30R-AK001 20 ug
EUR 273
Description: Purified recombinant Mouse KC protein

Anti-CXCL1 antibody
STJ28366 100 µl
EUR 277
Description: This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression of this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4.

Anti-CXCL1 antibody
STJ72026 100 µg
EUR 260

Rabbit Polyclonal antibody Anti-CRBN
Anti-CRBN 50 µg
EUR 349

KC antibody
70R-KR006 50 ug
EUR 273
Description: Affinity purified Rabbit polyclonal KC antibody

KC antibody
20R-1786 100 ug
EUR 651
Description: Rabbit polyclonal KC antibody

KC antibody
70R-12297 100 ug
EUR 527
Description: Rabbit polyclonal KC antibody

KC antibody
70R-12298 100 ug
EUR 492
Description: Rabbit polyclonal KC antibody

KC Antibody
5211-100
EUR 376

KC Antibody
5212-100
EUR 392

KC Antibody
5212-30T
EUR 146

Rabbit Anti Mouse Cxcl1 Polyclonal Antibody
CPBT-65100RM 0.1 mg
EUR 881

anti-7-ketocholesterol (7-KC) (35A)
LF-MA90006 20 ug
EUR 1025
Description: Mouse monoclonal to 7-ketocholesterol (7-KC)

anti-7-ketocholesterol (7-KC) (35A)
LF-MA90007 100 ug
EUR 2725
Description: Mouse monoclonal to 7-ketocholesterol (7-KC)

KC Blocking Peptide
33R-11041 50 ug
EUR 191
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of KC antibody, catalog no. 70R-12298

KC Blocking Peptide
5212BP-50
EUR 153

Polyclonal KC Antibody
APR16969G 0.1mg
EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human KC . This antibody is tested and proven to work in the following applications:

KC 12291 hydrochloride
B7332-10 10 mg
EUR 373

KC 12291 hydrochloride
B7332-50 50 mg
EUR 1363

Anti-GRO alpha/Cxcl1 Antibody
A00533 100ug/vial
EUR 294

Anti-GRO alpha/CXCL1 Antibody
PA1760 100ug/vial
EUR 294

KiloGreen 2X qPCR MasterMix-iCycler
MasterMix-KC 4 x 1.25 ml - 500 reactions (20 ul)
EUR 140

Mouse CXCL1 ELISA Kit
55R-1741 1 kit
EUR 624
Description: ELISA kit for detection of CXCL1 in the research laboratory

Mouse CXCL1 shRNA Plasmid
20-abx970673
  • EUR 801.00
  • EUR 1121.00
  • 150 µg
  • 300 µg

GRO-alpha/CXCL1, Mouse
HY-P7188 50ug
EUR 533

Mouse keinocyte chemoattractant (KC) ELISA kit
E03K0088-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Mouse keinocyte chemoattractant (KC) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse keinocyte chemoattractant (KC) ELISA kit
E03K0088-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Mouse keinocyte chemoattractant (KC) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse keinocyte chemoattractant (KC) ELISA kit
E03K0088-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Mouse keinocyte chemoattractant (KC) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

CXCL1/GRO
EF012822 96 Tests
EUR 689

pEGFP- CXCL1
PVT10178 2 ug
EUR 301

CXCL1 protein
30R-3156 50 ug
EUR 257
Description: Purified recombinant CXCL1 protein

CXCL1 antibody
70R-16681 50 ul
EUR 435
Description: Rabbit polyclonal CXCL1 antibody

CXCL1 antibody
70R-10502 50 ug
EUR 467
Description: Affinity purified rabbit polyclonal CXCL1 antibody

CXCL1 antibody
70R-14297 100 ug
EUR 327
Description: Affinity purified Rabbit polyclonal CXCL1 antibody

CXCL1 antibody
70R-15473 100 ug
EUR 327
Description: Rabbit polyclonal CXCL1 antibody

CXCL1 Antibody
1-CSB-PA009036
  • EUR 222.00
  • EUR 195.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against CXCL1. Recognizes CXCL1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: IHC, ELISA;IHC:1/100-1/300.ELISA:1/10000

CXCL1 Antibody
1-CSB-PA006239GA01HU
  • EUR 597.00
  • EUR 333.00
  • 150ul
  • 50ul
Description: A polyclonal antibody against CXCL1. Recognizes CXCL1 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC

CXCL1 Antibody
1-CSB-PA06097A0Rb
  • EUR 317.00
  • EUR 335.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against CXCL1. Recognizes CXCL1 from Human. This antibody is Unconjugated. Tested in the following application: ELISA

Cxcl1 Antibody
1-CSB-PA09217A0Rb
  • EUR 317.00
  • EUR 335.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against Cxcl1. Recognizes Cxcl1 from Mouse. This antibody is Unconjugated. Tested in the following application: ELISA

CXCL1 siRNA
20-abx913248
  • EUR 551.00
  • EUR 732.00
  • 15 nmol
  • 30 nmol

CXCL1 siRNA
20-abx913249
  • EUR 551.00
  • EUR 732.00
  • 15 nmol
  • 30 nmol

CXCL1 siRNA
20-abx901350
  • EUR 551.00
  • EUR 732.00
  • 15 nmol
  • 30 nmol

CXCL1 Antibody
33054-100ul 100ul
EUR 252

CXCL1/GRO
E21-597 10ug
EUR 343

CXCL1 Antibody
43679-100ul 100ul
EUR 252

Polyclonal Goat anti-GST α-form
GST-ANTI-1 50 uL
EUR 280

Polyclonal Goat anti-GST μ-form
GST-ANTI-2 50 uL
EUR 280

Polyclonal Goat anti-GST p-form
GST-ANTI-3 50 uL
EUR 280

GRO/KC, murine recombinant
4210-100
EUR 773

GRO/KC, murine recombinant
4210-1000
EUR 3856

GRO/KC, murine recombinant
4210-20
EUR 256

Rabbit Anti Rat Cxcl1 Polyclonal Antibody
CPBT-65101RR 0.1 mg
EUR 881

CXCL1 protein (Mouse) (His tag)
80R-3368 50 ug
EUR 257
Description: Purified recombinant CXCL1 protein (Mouse) (His tag)

CXCL1 protein (Mouse) (His tag)
80R-3439 50 ug
EUR 257
Description: Purified recombinant CXCL1 protein (Mouse) (His tag)

Mouse CXCL1/GROα ELISA kit
LF-EK50473 1×96T
EUR 648

Cxcl1 ORF Vector (Mouse) (pORF)
ORF042286 1.0 ug DNA
EUR 95

Mouse CXCL1 Detection Assay Kit
6725 1 kit
EUR 483.55
Description: Mouse CXCL1 Detection Assay Kit

Mouse CXCL1 PicoKine ELISA Kit
EK0723 96 wells
EUR 456
Description: For quantitative detection of mouse CXCL1 in cell culture supernates and serum.

ELISA kit for Mouse CXCL1
EK5299 96 tests
EUR 553
Description: Enzyme-linked immunosorbent assay kit for quantification of Mouse CXCL1 in samples from serum, plasma, tissue homogenates and other biological fluids.

CXCL1 ELISA Kit (Mouse) (OKCD05712)
OKCD05712 96 Wells
EUR 609
Description: Description of target: This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This secretory protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils. In mouse, deficiency of this gene is associated with colitis and with defects in immune cell recruitment to the lung.;Species reactivity: Mouse;Application: ELISA;Assay info: ;Sensitivity: < 6.0pg/mL

CXCL1 ELISA Kit (Mouse) (OKAN04583)
OKAN04583 96 Wells
EUR 792
Description: Description of target: This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This secretory protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils. In mouse, deficiency of this gene is associated with colitis and with defects in immune cell recruitment to the lung.;Species reactivity: Mouse;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 6.0 pg/mL

CXCL1 ELISA Kit (Mouse) (OKBB00312)
OKBB00312 96 Tests
EUR 544
Description: Description of target: Chemokine (C-X-C motif) ligand 1 (CXCL1) is a small cytokine belonging to the CXC chemokine family that was previously called GRO1 oncogene, GROα, KC, Neutrophil-activating protein 3 (NAP-3) and melanoma growth stimulating activity, alpha (MSGA-α). In humans, this protein is encoded by the CXCL1 gene. The gene for CXCL1 is located on human chromosome 4 amongst genes for other CXC chemokines. The mature form of CXCL1 is maximally 73 amino acids long. CXCL1 is secreted by human melanoma cells, has mitogenic properties and is implicated in melanoma pathogenesis. CXCL1 is expressed by macrophages, neutrophils and epithelial cells, and has neutrophil chemoattractant activity. This chemokine elicits its effects by signaling through the chemokine receptor CXCR2.CXCL1 decreased the severity of multiple sclerosis and may offer a neuro-protective function. The standard product used in this kit is recombinant mouse CXCL1, consisting of 77 amino acids with the molecular mass of 8KDa.;Species reactivity: Mouse;Application: ELISA;Assay info: ;Sensitivity: < 1 pg/ml

KC ELISA Kit (Mouse) : 96 Wells (OKAG00090)
OKAG00090 96 Wells
EUR 596
Description: Description of target: This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This secretory protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils. In mouse, deficiency of this gene is associated with colitis and with defects in immune cell recruitment to the lung.;Species reactivity: Mouse;Application: ELISA;Assay info: Quantitative Colorimentric Sandwich ELISA;Sensitivity: 8 pg/mL

CXCL1 Blocking Peptide
33R-7741 100 ug
EUR 180
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of CXCL1 antibody, catalog no. 70R-10502

CXCL1 antibody (HRP)
60R-2236 100 ug
EUR 327
Description: Rabbit polyclonal CXCL1 antibody (HRP)

CXCL1 antibody (FITC)
60R-2237 100 ug
EUR 327
Description: Rabbit polyclonal CXCL1 antibody (FITC)

CXCL1 antibody (biotin)
60R-2238 100 ug
EUR 327
Description: Rabbit polyclonal CXCL1 antibody (biotin)

CXCL1 cloning plasmid
CSB-CL006239HU-10ug 10ug
EUR 233
Description: A cloning plasmid for the CXCL1 gene.

pCMV-SPORT6-CXCL1
PVT13291 2 ug
EUR 391

CXCL1 Blocking Peptide
20-abx061039
  • EUR 286.00
  • EUR 425.00
  • 1 mg
  • 5 mg

Cxcl1 Polyclonal Antibody
A51950 100 µg
EUR 570.55
Description: fast delivery possible

CXCL1 Polyclonal Antibody
A51978 100 µg
EUR 570.55
Description: kits suitable for this type of research

CXCL1 Conjugated Antibody
C33054 100ul
EUR 397

Recombinant Human CXCL1
P0207 100ug
EUR 522.36
Description: Recombinant Human protein for CXCL1

Recombinant Human CXCL1
P0109 100ug
EUR 522.36
Description: Recombinant Human protein for CXCL1

Mouse Growth-regulated alpha protein (Cxcl1)
1-CSB-RP092174m
  • EUR 505.00
  • EUR 265.00
  • EUR 1827.00
  • EUR 766.00
  • EUR 1218.00
  • EUR 335.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Mouse Growth-regulated alpha protein(Cxcl1),partial expressed in E.coli

Mouse CXCL1/GROα ELISA kit (4X96T)
LF-EK50474 4×96T
EUR 2201

Cxcl1 sgRNA CRISPR Lentivector set (Mouse)
K4368201 3 x 1.0 ug
EUR 339

Mouse CXCL1 AssayLite Antibody (FITC Conjugate)
70027-05141 150 ug
EUR 428

GRO-alpha/CXCL1 (CHO-expressed), Mouse
HY-P7186 50ug
EUR 337

Human keinocyte chemoattractant (KC) ELISA kit
E01K0088-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Human keinocyte chemoattractant (KC) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human keinocyte chemoattractant (KC) ELISA kit
E01K0088-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Human keinocyte chemoattractant (KC) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human keinocyte chemoattractant (KC) ELISA kit
E01K0088-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Human keinocyte chemoattractant (KC) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat keinocyte chemoattractant (KC) ELISA kit
E02K0088-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Rat keinocyte chemoattractant (KC) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Breast cancer (BRCA) genetesting in ovarian cancer

The discovery of cancer-causing BRCA1/2 mutations and the emergence of genetic testing have brought precision in patient selection for poly-(ADP)-ribose polymerase inhibitor (PARPi) treatment. Interestingly, patients who are carriers of BRCA1/2 mutations have a higher risk for developing cancer, but respond better to DNA-damaging cytotoxic therapy, such as platinum-based chemotherapy.
The distinctive biology of ovarian cancer involves high genomic instability consisting of gene amplification, gene deletion, oncogene hypomethylation, loss of heterozygosity, and tumor suppressor gene promoter hypermethylation in many of the DNA damage response (DDR) genes, including BRCA1/2. Several of these genetic abnormalities can impair high fidelity DNA damage repair increasing the therapeutic audience for PARPi’s. This is especially important given the clinical development over the last decade of this group of agents and the dramatic increase in progression free survival among ovarian cancer patients who received PARPi, both in treatment or maintenance setting. In this review, we summarize our current understanding of the role of BRCA1/2 mutations in ovarian cancer and present relevant clinical trials in which BRCA1/2 was investigated as biomarker for therapy. We also outline the role of homologous recombination (HR) deficiency as biomarker by presenting the recent clinical development and recent approvals PARPi for firstline maintenance in ovarian cancer.

Haplotyping by linked-read sequencing (HLRS) of the genetic disease carriers for preimplantation genetictesting without a proband or relatives

Background: In order to mitigate the risk of allele dropout (ADO) and ensure the accuracy of preimplantation genetic testing for monogenic disease (PGT-M), it is necessary to construct parental haplotypes. Typically, haplotype resolution is obtained by genotyping multiple polymorphic markers in both parents and a proband or a relative. Sometimes, single sperm typing, or tests on the polar bodies may also be useful. Nevertheless, this process is time-consuming. At present, there was no simple linkage analysis strategy for patients without affected relatives.
Method: To solve this problem, we established a haplotyping by linked-read sequencing (HLRS) method without the requirement for additional relatives. First, the haplotype of the genetic disease carriers in the family was constructed by linked-read sequencing, and then the informative single nucleotide polymorphisms (SNPs) in upstream and downstream mutation region were selected to construct the embryo haplotype and to determine whether the embryo was carrying the mutation. Two families were selected to validate this method; one with alpha thalassemia and the other with NDP gene disorder.
Results: The haplotyping by linked-read sequencing (HLRS) method was successfully applied to construct parental haplotypes without recruiting additional family members; the method was also validated for PGT-M. The mutation carriers in these families were sequenced by linked-read sequencing, and their haplotypes were successfully phased. Adjacent SNPs of the mutation gene were identified.
The informative SNPs were chosen for linkage analyses to identify the carrier embryos. For the alpha thalassemia family, a normal blastocyst was transferred to the uterus and the accuracy of PGT-M was confirmed by amniocentesis at 16 weeks of gestation.
Conclusions: Our results suggest that HLRS can be applied for PGT-M of monogenic disorders or de novo mutations where the mutations haplotype cannot be determined due to absence of affected relatives.

Anti-CD163
DB-045-0.5 500 μl
EUR 384
Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated

Anti-CD163
DB-045-1 1 ml
EUR 613
Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated

Anti-CD163
DB-045-RTU-15 15 ml
EUR 354
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-CD163
DB-045-RTU-7 7 ml
EUR 231
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-CD163
DB045RTU-15 15 ml
EUR 354
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-CD163
DB045RTU-7 7 ml
EUR 231
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Mouse Cluster Of Differentiation (CD163) ELISA Kit
DLR-CD163-Mu-48T 48T
EUR 508
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Cluster Of Differentiation (CD163) in samples from serum, plasma or other biological fluids.

Mouse Cluster Of Differentiation (CD163) ELISA Kit
DLR-CD163-Mu-96T 96T
EUR 661
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Cluster Of Differentiation (CD163) in samples from serum, plasma or other biological fluids.

Rat Cluster Of Differentiation (CD163) ELISA Kit
DLR-CD163-Ra-48T 48T
EUR 508
Description: A sandwich quantitative ELISA assay kit for detection of Rat Cluster Of Differentiation (CD163) in samples from serum, plasma, tissue homogenates or other biological fluids.

Rat Cluster Of Differentiation (CD163) ELISA Kit
DLR-CD163-Ra-96T 96T
EUR 661
Description: A sandwich quantitative ELISA assay kit for detection of Rat Cluster Of Differentiation (CD163) in samples from serum, plasma, tissue homogenates or other biological fluids.

Mouse Cluster Of Differentiation (CD163) ELISA Kit
RD-CD163-Mu-48Tests 48 Tests
EUR 511

Mouse Cluster Of Differentiation (CD163) ELISA Kit
RD-CD163-Mu-96Tests 96 Tests
EUR 709

Rat Cluster Of Differentiation (CD163) ELISA Kit
RD-CD163-Ra-48Tests 48 Tests
EUR 511

Rat Cluster Of Differentiation (CD163) ELISA Kit
RD-CD163-Ra-96Tests 96 Tests
EUR 709

Mouse Cluster Of Differentiation (CD163) ELISA Kit
RDR-CD163-Mu-48Tests 48 Tests
EUR 534

Mouse Cluster Of Differentiation (CD163) ELISA Kit
RDR-CD163-Mu-96Tests 96 Tests
EUR 742

Rat Cluster Of Differentiation (CD163) ELISA Kit
RDR-CD163-Ra-48Tests 48 Tests
EUR 534

Rat Cluster Of Differentiation (CD163) ELISA Kit
RDR-CD163-Ra-96Tests 96 Tests
EUR 742

Rabbit Polyclonal antibody Anti-CRBN
Anti-CRBN 50 µg
EUR 349

Anti-CD163 Antibody
A00812-1 100ug/vial
EUR 334

Anti-CD163 antibody
STJ160082 1 mL C
EUR 941

Anti-CD163 antibody
STJ16100302 100 µg
EUR 720

Anti-CD163 antibody
STJ16100324 1 mL
EUR 979

Anti-CD163 antibody
STJ180301 0.1 ml
EUR 215

Anti-CD163 antibody
STJ190009 200 µl
EUR 197
Description: Unconjugated Mouse monoclonal to CD163 (AS1A1)

Anti-CD163 Antibody
STJ500423 100 µg
EUR 476

Anti-CD163 Antibody
STJ500424 100 µg
EUR 476

Anti-CD163 antibody
STJ110681 100 µl
EUR 277
Description: The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Anti-CD163 Antibody
PA1874 100ug/vial
EUR 294

Anti-CD163 Antibody
PA1874-1 100ug/vial
EUR 334

Anti-CD163/M130 antibody
PAab09771 100 ug
EUR 355

Anti-CD163/M130 Antibody
A00812 100ul
EUR 397
Description: Rabbit IgG polyclonal antibody for Scavenger receptor cysteine-rich type 1 protein M130 (CD163) detection.tested for IF, IHC, WB in Human, Mouse, Rat. Various direct flourescent conjugates are available for FCM upon request. Please contact us for details.

Anti-Hu CD163 Purified
11-645-C025 0.025 mg
EUR 99

Anti-Hu CD163 Purified
11-645-C100 0.1 mg
EUR 158

Anti-Hu CD163 APC
1A-645-T025 25 tests
EUR 140

Anti-Hu CD163 APC
1A-645-T100 100 tests
EUR 240

Anti-Hu CD163 PE
1P-645-T025 25 tests
EUR 140

Anti-Hu CD163 PE
1P-645-T100 100 tests
EUR 240

Anti-CD163 Antibody BIOTIN
STJ500425 100 µg
EUR 586

Anti-CD163 Antibody FITC
STJ500426 100 µg
EUR 586

Anti-CD163 Antibody BIOTIN
STJ500427 100 µg
EUR 586

Anti-CD163 Antibody FITC
STJ500428 100 µg
EUR 586

anti- CD163/M130 Antibody
FNab09771 100µg
EUR 548.75
Description: Antibody raised against CD163/M130 

human CD163 antigen,CD163 LISA kit
201-12-0247 96 tests
EUR 440
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human CD163 antigen(CD163)ISA kit
GA-E0263HM-48T 48T
EUR 289

Human CD163 antigen(CD163)ISA kit
GA-E0263HM-96T 96T
EUR 466

Human CD163 antigen(CD163)ISA kit
QY-E05066 96T
EUR 361

Mouse Anti Human Cd163 Monoclonal Antibody
CABT-47162MH 25 µg
EUR 372

Mouse Anti Human Cd163 Monoclonal Antibody
CABT-47163MH 0.2 mg
EUR 881

Polyclonal Goat anti-GST α-form
GST-ANTI-1 50 uL
EUR 280

Polyclonal Goat anti-GST μ-form
GST-ANTI-2 50 uL
EUR 280

Polyclonal Goat anti-GST p-form
GST-ANTI-3 50 uL
EUR 280

Anti-Hu CD163 PE-Cy7
T7-645-T025 25 tests
EUR 154

Anti-Hu CD163 PE-Cy7
T7-645-T100 100 tests
EUR 268

Anti-Hu CD163 PerCP-Cy5.5
T9-645-T025 25 tests
EUR 196

Anti-Hu CD163 PerCP-Cy5.5
T9-645-T100 100 tests
EUR 352

Anti-CD163 Rabbit Monoclonal Antibody
M00812 100ug/vial
EUR 397
Description: Rabbit Monoclonal CD163 Antibody. Validated in IP, WB and tested in Human.

Porcine CD163 antigen,CD163 LISA kit
GA-E0045PC-48T 48T
EUR 364

Porcine CD163 antigen,CD163 LISA kit
GA-E0045PC-96T 96T
EUR 590

Canine CD163 antigen(CD163 LISA kit
GA-E0062CN-48T 48T
EUR 402

Canine CD163 antigen(CD163 LISA kit
GA-E0062CN-96T 96T
EUR 684

CD163 Antibody
ABD8235 100 ug
EUR 438

CD163 antibody
10R-CD163aRT 250 ug
EUR 716
Description: Mouse monoclonal CD163 antibody

CD163 antibody
10R-6496 100 ug
EUR 203
Description: Mouse monoclonal CD163 antibody

CD163 Antibody
DF8235 200ul
EUR 304
Description: CD163 Antibody detects endogenous levels of total CD163.

CD163 Antibody
1-CSB-PA969205
  • EUR 317.00
  • EUR 244.00
  • 100ul
  • 50ul
Description: A polyclonal antibody against CD163. Recognizes CD163 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:1000-1:2000, IHC:1:25-1:100

CD163 Antibody
1-CSB-PA801238LA01HU
  • EUR 317.00
  • EUR 335.00
  • 100ul
  • 50ul
Description: A polyclonal antibody against CD163. Recognizes CD163 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IF; Recommended dilution: IF:1:50-1:200

Cd163 Antibody
1-CSB-PA650452LA01MO
  • EUR 317.00
  • EUR 335.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against Cd163. Recognizes Cd163 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB; Recommended dilution: WB:1:500-1:2000

CD163 siRNA
20-abx910930
  • EUR 551.00
  • EUR 732.00
  • 15 nmol
  • 30 nmol

CD163 siRNA
20-abx910931
  • EUR 551.00
  • EUR 732.00
  • 15 nmol
  • 30 nmol

CD163 Antibody
20-abx242956
  • EUR 467.00
  • EUR 328.00
  • 100 ul
  • 50 ul

CD163 Antibody
37157-100ul 100ul
EUR 252

CD163 Antibody
49553-100ul 100ul
EUR 333

CD163 Antibody
49553-50ul 50ul
EUR 239

Human CD163 ELISA Kit
ELA-E1726h 96 Tests
EUR 824

Human CD163 ELISA Kit
LF-EK50890 1×96T
EUR 648

Human CD163 shRNA Plasmid
20-abx956176
  • EUR 801.00
  • EUR 1121.00
  • 150 µg
  • 300 µg

Mouse Anti Rat Cd163 Monoclonal Antibody
DMABT-47170MR 0.25 mg
EUR 741

Mouse Anti Rat Cd163 Monoclonal Antibody
DMABT-47171MR 0.1 mg
EUR 559

Anti-Human CD163 DyLight® 488 conjugated Antibody
A00812-Dyl488 100ug/vial
EUR 344

Anti-Human CD163 DyLight® 550 conjugated Antibody
A00812-Dyl550 100ug/vial
EUR 344

Mouse Anti-Human CD163 monoclonal antibody, clone JID274
CABT-L2938-100uL500uL 100 uL, 500 uL
EUR 502

Human CellExp? CD163, Human recombinant
9226-10
EUR 305

Human CellExp? CD163, Human recombinant
9226-50
EUR 773

Mouse Anti Pig Cd163 Monoclonal Antibody,FITC
CABT-47164MP 0.1 mg
EUR 881

Mouse Anti Pig Cd163 Monoclonal Antibody,RPE
CABT-47166MP 100 TEST
EUR 715

Anti-CD163 Rabbit Monoclonal Antibody, Clone#RM371
M00812-1 100uL
EUR 385
Description: Anti-CD163 Rabbit Monoclonal Antibody, Clone#RM371 tested in WB, IHC, reactive to Human

Mouse Anti Rat Cd163 Monoclonal Antibody,Biotin
DMABT-47168MR 0.1 mg
EUR 881

Mouse Anti Rat Cd163 Monoclonal Antibody,FITC
DMABT-47169MR 0.1 mg
EUR 881

Mouse Anti Rat Cd163 Monoclonal Antibody,RPE
DMABT-47172MR 100 TEST
EUR 892

CD163 antibody (PE)
61R-1319 100 tests
EUR 403
Description: Mouse monoclonal CD163 antibody (PE)

CD163 antibody (biotin)
61R-1569 100 ug
EUR 349
Description: Mouse monoclonal CD163 antibody (biotin)

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