A 2020 update on the use of genetic testing for patients

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myasthenickids

A 2020 update on the use of genetic testing for patients with primary immunodeficiency

  • Introduction: Genetic testing of patients with clinically diagnosed or suspected primary immunodeficiencies (PIDs) constitutes standard of care. Choice of testing modality and patient attributes can impact the likelihood of securing a diagnosis.
  • Areas covered: Published diagnostic rates for gene panel testing, exome sequencing (WES), and whole genome sequencing are compared among cohorts identified within PubMed. Performance of the testing platforms is reviewed in PIDs taken as a whole, followed by separate cohorts of patients with suspected PIDs, specific PIDs, and clinical phenotypes that can be associated with underlying PIDs.
  • Expert opinion: Massively parallel high throughput sequencing clearly represents the most expedient method for diagnosis of PIDs. For patients from highly consanguineous backgrounds, WES and whole genome sequencing should be performed to obtain optimal diagnostic yield. For patients for whom familial consanguinity is unlikely, choice of platform depends upon the phenotype. In patients with suspected PIDs, assessment for copy number variants is important, whether as part of gene panel bioinformatic analyses or combined with WES.
  • Diagnostic rates overall for massively parallel sequencing are high for clinically diagnosed and suspected PIDs. WES may have a slightly higher overall yield, but gene panel testing represents a cost effective and efficient reasonable initial step.
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myasthenickids

Mouse GRO/KC (CXCL1), (Recombinant)

22060572-1 5 µg
EUR 146.42

Recombinant Mouse GRO/KC (CXCL1)

7-01858 5µg Ask for price

Recombinant Mouse GRO/KC (CXCL1)

7-01859 20µg Ask for price

Recombinant Mouse GRO/KC (CXCL1)

7-01860 1mg Ask for price

GRO1/KC Mouse Recombinant (CXCL1)

rAP-0159 Inquiry Ask for price

Recombinant Mouse (E.Coli) GRO/KC (CXCL1)

RP-1037 5 ug
EUR 196.8

GRO1/KC Mouse Recombinant Protein (CXCL1)

PROTP12850-1 Regular: 20ug
EUR 380.4
Description: KC Mouse Recombinant also known as N51 and GRO1 produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 77 amino acids and having a molecular mass of approximately 8 kDa.;The GRO-1 is purified by proprietary chromatographic techniques.

GRO1/KC Mouse, GRO/KC (CXCL1) Mouse Recombinant Protein, His Tag

PROTP12850 Regular: 20ug
EUR 380.4
Description: GRO1/KC Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 97 amino acids (25-96 a.a.) and having a molecular mass of 10.5kDa.;GRO1 is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Recombinant Mouse Cxcl1/KC Protein, His Tag

E40MOP2119 20ug
EUR 495

GRO/KC (CXCL1) Mouse Recombinant, His Tag

rAP-0149 Inquiry Ask for price

GRO-alpha, KC, CXCL1 (rMuKC), murine (mouse)

RC332-12 5ug
EUR 125.26

GRO / KC (CXCL1) Protein

20-abx261870
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  • Ask for price
  • 1 mg
  • 20 ug
  • 5 ug

GRO / KC (CXCL1) Protein

20-abx260684
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  • Ask for price
  • 1 mg
  • 20 ug
  • 5 ug

GRO / KC (CXCL1) Protein

abx261870-10mg 10 mg
EUR 325

GRO / KC (CXCL1) Protein

abx261870-25mg 25 mg
EUR 4625

GRO / KC (CXCL1) Protein

abx261870-5mg 5 mg
EUR 225

GRO / KC (CXCL1) Protein

abx260684-10g 10 µg
EUR 325

GRO / KC (CXCL1) Protein

abx260684-2g 2 µg
EUR 225

Recombinant Murine KC/CXCL1

AP60329 100ug
EUR 896

Mouse CXC-chemokine ligand 1(CXCL1/KC)ELISA Kit

YLA0122MO-48T 48T Ask for price

Mouse CXC-chemokine ligand 1(CXCL1/KC)ELISA Kit

YLA0122MO-96T 96T Ask for price

Rat CXCL1/KC ELISA Kit

E28L0667 96T
EUR 666.67

GRO, KC, CXCL1, rRtGRO, rat

RC352-12 5ug
EUR 125.26

Mouse CXC-Chemokine ligand 1, CXCL1/KC GENLISA ELISA

KLM1520 1 x 96 wells
EUR 341

GRO/KC (CXCL1), Rat Recombinant

P1288-25 each
EUR 444

GRO/KC (CXCL1), Rat Recombinant

P1288-5 each
EUR 210

Recombinant Murine KC (CXCL1) Protein

PROTP12850-2 20ug
EUR 380.4
Description: All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant murine KC is a 7.8 kDa protein consisting of 72 amino acids including the 'ELR' motif common to the CXC chemokine family that bind to CXCR1 or CXCR2.

Recombinant Rat GRO/KC (CXCL1) Protein

PROTP14095-1 25ug
EUR 380.4
Description: All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant rat GRO/KC is a 7.8 kDa protein consisting of 72 amino acids including the 'ELR' motif common to the CXC chemokine family that bind to CXCR1 or CXCR2.

Rat GRO/KC (CXCL1) Recombinant Protein

R20-003 25 µg
EUR 196.35
Description: All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant rat GRO/KC is a 7.8 kDa protein consisting of 72 amino acids including the 'ELR' motif common to the CXC chemokine family that bind to CXCR1 or CXCR2.

Rat GRO/KC (CXCL1) Recombinant Protein

R20-003S 5 µg
EUR 92.4
Description: All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant rat GRO/KC is a 7.8 kDa protein consisting of 72 amino acids including the 'ELR' motif common to the CXC chemokine family that bind to CXCR1 or CXCR2.

KC/CXCL1 (gro-alpha) (Recombinant) Murine

GWB-3646DB 0.02 mg Ask for price

Rat CXCL1/CINC-1/KC ELISA Kit

RK00196 96 Tests
EUR 280

Mouse CXCL1

QY-E21800 96T
EUR 420

Mouse CXCL1 Antibody

GWB-28E0B5 0.1 mg Ask for price

Rabbit Anti Mouse Cxcl1 Polyclonal Antibody

CPBT-65100RM 0.1 mg
EUR 1057.2

CXCL1, Mouse

E34M009M 5 μg
EUR 155

Mouse IL-8/CXCL1/CXCL1 ELISA Kit

E16ME0008 96T
EUR 833.33

Anti-Mouse CXCL1 Antibody

103-M353 100 µg
EUR 399
Description: All three isoforms of GRO (or CXCL1) are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant murine KC is a 7.8 kDa protein consisting of 72 amino acids including the 'ELR' motif common to the CXC chemokine family that bind to CXCR1 or CXCR2.

Mouse CXCL1 Antibody (Biotin)

GWB-395E8D 0.05 mg Ask for price

Recombinant Mouse CXCL1

Z200345 25 µg
EUR 85
Description: Growth regulated oncogene-alpha belongs to the family of chemotyctic cytokines called chemokines. It is identical with MGSA (melanoma growth stimulatory activity)and the new designation is CXCL1. This factor is known mainly because of its chemotactic activity. GRO expression is inducible by serum or PDGF and/or by a variety of inflammatory mediators, such as IL-1 and TNF, in monocytes, fibroblasts, melanocytes and epithelial cells. In certain tumor cell lines, GRO is expressed constitutively. Similar to other alpha chemokines, the three GRO proteins are potent neutrophil attractants and activators. In addition, these chemokines are also active toward basophils. All three GROs can bind with high affinity to the IL-8 receptor type B.

Recombinant Mouse CXCL1

Z200347 100 µg
EUR 265
Description: Growth regulated oncogene-alpha belongs to the family of chemotyctic cytokines called chemokines. It is identical with MGSA (melanoma growth stimulatory activity)and the new designation is CXCL1. This factor is known mainly because of its chemotactic activity. GRO expression is inducible by serum or PDGF and/or by a variety of inflammatory mediators, such as IL-1 and TNF, in monocytes, fibroblasts, melanocytes and epithelial cells. In certain tumor cell lines, GRO is expressed constitutively. Similar to other alpha chemokines, the three GRO proteins are potent neutrophil attractants and activators. In addition, these chemokines are also active toward basophils. All three GROs can bind with high affinity to the IL-8 receptor type B.

Recombinant Mouse CXCL1

Z200349 1.0 mg
EUR 2025
Description: Growth regulated oncogene-alpha belongs to the family of chemotyctic cytokines called chemokines. It is identical with MGSA (melanoma growth stimulatory activity)and the new designation is CXCL1. This factor is known mainly because of its chemotactic activity. GRO expression is inducible by serum or PDGF and/or by a variety of inflammatory mediators, such as IL-1 and TNF, in monocytes, fibroblasts, melanocytes and epithelial cells. In certain tumor cell lines, GRO is expressed constitutively. Similar to other alpha chemokines, the three GRO proteins are potent neutrophil attractants and activators. In addition, these chemokines are also active toward basophils. All three GROs can bind with high affinity to the IL-8 receptor type B.

Mouse Monoclonal anti-human CXCL1 (GRO alpha)

hAP-0208 100ug
EUR 250

CXCL1 (33-96) (Mouse)

045-48 100 μg
EUR 389.88

Rat CXCL1/CINC-1/KC(IL-8) ELISA kit

E22-RC008.48 48T
EUR 295

Rat CXCL1/CINC-1/KC(IL-8) ELISA kit

E22-RC008.96 96T
EUR 395

Mouse Monoclonal anti-human GRO (CXCL1/2/3)

hAP-1217 100ug
EUR 250

Mouse Monoclonal anti-human GRO (CXCL1/2/3)

hAP-1217A 50ug
EUR 400

Mouse CXCL1 ELISA Kit

EK5299 96 tests
EUR 599

Mouse CXCL1 ELISA Kit

55R-1741 1 kit
EUR 667
Description: ELISA kit for detection of CXCL1 in the research laboratory

Mouse CXCL1 ELISA Kit

GWB-ZZD141 1x96 well plate Ask for price

Mouse CXCL1 shRNA Plasmid

20-abx970673
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  • 150 µg
  • 300 µg

Rat Monoclonal anti-mouse CXCL1

mAP-0201 100ug
EUR 250

[Tyr0]-CXCL1 (33-96) (Mouse)

045-46 100 μg
EUR 400.68

GRO-alpha/CXCL1, Mouse

HY-P7188 50ug
EUR 639.6

Mouse Monoclonal anti-human CXCL1/2/3 (Pan GRO)

hAP-0214 100ug
EUR 250

Mouse Monoclonal anti-human CXCL1/2/3 (Pan GRO)

hAP-0214A 50ug
EUR 400

Mouse CXCL1/GROα ELISA kit

LF-EK50473 1×96T
EUR 777.6

Mouse CXCL1 Detection Assay Kit

6725 1 kit
EUR 357
Description: Culture Media, Serum, Plasma

Anti-GROa(CXCL1) Antibody

Y123166 100 µl
EUR 320

Anti-Human CXCL1 Antibody

101-M347 100 µg
EUR 399
Description: Cotton rat growth-regulatedprotein (GRO) is a member of the ELR+ CXC subfamily of chemokines. The cotton rat GRO cDNA encodes a 100 amino acid (aa) precursor protein with a 27 aa putative signal peptide and a 73 aa mature protein. The predicted amino acid sequence of the mouse KC gene product indicates KC is a member of the CXC subfamily of chemokines. The protein sequence of mouse KC shows approximately 63% identity to that of mouse MIP-2. In addition, the protein sequence of KC is approximately 60% identical to the human GROs. It has been suggested that mouse KC and MIP-2 are the homologs of the human GROs and rat CINCs. KC mRNA is expressed in macrophages, endothelial cells, and fibroblasts.

CXCL1 protein (Mouse) (His tag)

80R-3368 50 ug
EUR 587
Description: Purified recombinant CXCL1 protein (Mouse) (His tag)

CXCL1 protein (Mouse) (His tag)

80R-3439 50 ug
EUR 308.4
Description: Purified recombinant CXCL1 protein (Mouse) (His tag)

Cxcl1 ORF Vector (Mouse) (pORF)

ORF042286 1.0 ug DNA
EUR 114

CXCL1 ELISA Kit (Mouse) (OKCD05712)

OKCD05712 96 Wells
EUR 730.8
Description: Description of target: This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This secretory protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils. In mouse, deficiency of this gene is associated with colitis and with defects in immune cell recruitment to the lung.;Species reactivity: Mouse;Application: ELISA;Assay info: ;Sensitivity: < 6.0pg/mL

CXCL1 ELISA Kit (Mouse) (OKAN04583)

OKAN04583 96 Wells
EUR 950.4
Description: Description of target: This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This secretory protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils. In mouse, deficiency of this gene is associated with colitis and with defects in immune cell recruitment to the lung.;Species reactivity: Mouse;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 6.0 pg/mL

CXCL1 ELISA Kit (Mouse) (OKBB00312)

OKBB00312 96 Tests
EUR 652.8
Description: Description of target: Chemokine (C-X-C motif) ligand 1 (CXCL1) is a small cytokine belonging to the CXC chemokine family that was previously called GRO1 oncogene, GROα, KC, Neutrophil-activating protein 3 (NAP-3) and melanoma growth stimulating activity, alpha (MSGA-α). In humans, this protein is encoded by the CXCL1 gene. The gene for CXCL1 is located on human chromosome 4 amongst genes for other CXC chemokines. The mature form of CXCL1 is maximally 73 amino acids long. CXCL1 is secreted by human melanoma cells, has mitogenic properties and is implicated in melanoma pathogenesis. CXCL1 is expressed by macrophages, neutrophils and epithelial cells, and has neutrophil chemoattractant activity. This chemokine elicits its effects by signaling through the chemokine receptor CXCR2.CXCL1 decreased the severity of multiple sclerosis and may offer a neuro-protective function. The standard product used in this kit is recombinant mouse CXCL1, consisting of 77 amino acids with the molecular mass of 8KDa.;Species reactivity: Mouse;Application: ELISA;Assay info: ;Sensitivity: < 1 pg/ml

Cxcl1 (untagged) - Mouse chemokine (C-X-C motif) ligand 1 (Cxcl1), (10ug)

MC208599 10 µg Ask for price

Mouse CXCL1/GROα ELISA kit (4X96T)

LF-EK50474 4×96T
EUR 2641.2

Mouse CXCL1 AssayLite™ Antibody (FITC Conjugate)

70027-05141 150 ug
EUR 370

Cxcl1 (GFP-tagged) - Mouse chemokine (C-X-C motif) ligand 1 (Cxcl1), (10ug)

MG220966 10 µg Ask for price

Cxcl1 (Myc-DDK-tagged) - Mouse chemokine (C-X-C motif) ligand 1 (Cxcl1)

MR220966 10 µg Ask for price

Anti-GR alpha CXCL1 Antibody

A00533-1 100ul
EUR 380
Description: Boster Bio Anti-GR alpha CXCL1 Antibody catalog # A00533-1. Tested in ELISA, IHC applications. This antibody reacts with Human, Mouse, Rat.

Anti-GRO alpha/Cxcl1 Antibody

A00533 100ug/vial
EUR 352.8

Anti-GRO alpha/CXCL1 Antibody

PA1760 100ug/vial
EUR 352.8

Recombinant Mouse CXCL1 Protein (His Tag)

PKSM040992-10ug 10ug
EUR 129
Description: Mouse

Recombinant Mouse CXCL1 Protein (His Tag)

PKSM040992-50ug 50ug
EUR 375
Description: Mouse

Recombinant Mouse CXCL1/GRO-alpha Protein

RP01615 10μg
EUR 156

Recombinant Mouse CXCL1/GRO-alpha Protein

RP01641 10μg
EUR 195

OKCD05712-96W - CXCL1 ELISA Kit (Mouse)

OKCD05712-96W 96Wells
EUR 500

OKEH02714-96W - Cxcl1 ELISA Kit (Mouse)

OKEH02714-96W 96Wells
EUR 425

Mouse Chemokine Ligand CXCL1 ELISA Kit

IMSCXCL1KT each
EUR 729
Description: Mouse Chemokine Ligand CXCL1 ELISA Kit

GRO-alpha/CXCL1 (CHO-expressed), Mouse

HY-P7186 50ug
EUR 404.4

Cxcl1 sgRNA CRISPR Lentivector set (Mouse)

K4368201 3 x 1.0 ug
EUR 406.8

CXCL1 Antibody

33054 100ul
EUR 439

CXCL1 Antibody

33054-100ul 100ul
EUR 302.4

CXCL1 Antibody

43679 100ul
EUR 319

CXCL1 Antibody

43679-100ul 100ul
EUR 302.4

CXCL1 Antibody

E043679 100μg/100μl
EUR 255
Description: Available in various conjugation types.

CXCL1 Antibody

1-CSB-PA006239GA01HU
  • Ask for price
  • Ask for price
  • 150ul
  • 50ul
Description: A polyclonal antibody against CXCL1. Recognizes CXCL1 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC

CXCL1 Antibody

E95254 100ul
EUR 255
Description: Available in various conjugation types.

CXCL1 antibody

70R-14297 100 ug
EUR 530
Description: Affinity purified Rabbit polyclonal CXCL1 antibody

CXCL1 antibody

70R-15473 100 ug
EUR 302
Description: Rabbit polyclonal CXCL1 antibody

CXCL1 antibody

70R-16681 50 ul
EUR 289
Description: Rabbit polyclonal CXCL1 antibody

CXCL1 antibody

70R-10502 50 ug
EUR 467
Description: Affinity purified rabbit polyclonal CXCL1 antibody

CXCL1 Antibody

1-CSB-PA009036
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  • 100ug
  • 50ug
Description: A polyclonal antibody against CXCL1. Recognizes CXCL1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: IHC, ELISA;IHC:1/100-1/300.ELISA:1/10000

Breast cancer (BRCA) genetesting in ovarian cancer

The discovery of cancer-causing BRCA1/2 mutations and the emergence of genetic testing have brought precision in patient selection for poly-(ADP)-ribose polymerase inhibitor (PARPi) treatment. Interestingly, patients who are carriers of BRCA1/2 mutations have a higher risk for developing cancer, but respond better to DNA-damaging cytotoxic therapy, such as platinum-based chemotherapy.
The distinctive biology of ovarian cancer involves high genomic instability consisting of gene amplification, gene deletion, oncogene hypomethylation, loss of heterozygosity, and tumor suppressor gene promoter hypermethylation in many of the DNA damage response (DDR) genes, including BRCA1/2. Several of these genetic abnormalities can impair high fidelity DNA damage repair increasing the therapeutic audience for PARPi’s. This is especially important given the clinical development over the last decade of this group of agents and the dramatic increase in progression free survival among ovarian cancer patients who received PARPi, both in treatment or maintenance setting. In this review, we summarize our current understanding of the role of BRCA1/2 mutations in ovarian cancer and present relevant clinical trials in which BRCA1/2 was investigated as biomarker for therapy. We also outline the role of homologous recombination (HR) deficiency as biomarker by presenting the recent clinical development and recent approvals PARPi for firstline maintenance in ovarian cancer.

Haplotyping by linked-read sequencing (HLRS) of the genetic disease carriers for preimplantation genetictesting without a proband or relatives

Background: In order to mitigate the risk of allele dropout (ADO) and ensure the accuracy of preimplantation genetic testing for monogenic disease (PGT-M), it is necessary to construct parental haplotypes. Typically, haplotype resolution is obtained by genotyping multiple polymorphic markers in both parents and a proband or a relative. Sometimes, single sperm typing, or tests on the polar bodies may also be useful. Nevertheless, this process is time-consuming. At present, there was no simple linkage analysis strategy for patients without affected relatives.
Method: To solve this problem, we established a haplotyping by linked-read sequencing (HLRS) method without the requirement for additional relatives. First, the haplotype of the genetic disease carriers in the family was constructed by linked-read sequencing, and then the informative single nucleotide polymorphisms (SNPs) in upstream and downstream mutation region were selected to construct the embryo haplotype and to determine whether the embryo was carrying the mutation. Two families were selected to validate this method; one with alpha thalassemia and the other with NDP gene disorder.
Results: The haplotyping by linked-read sequencing (HLRS) method was successfully applied to construct parental haplotypes without recruiting additional family members; the method was also validated for PGT-M. The mutation carriers in these families were sequenced by linked-read sequencing, and their haplotypes were successfully phased. Adjacent SNPs of the mutation gene were identified.
The informative SNPs were chosen for linkage analyses to identify the carrier embryos. For the alpha thalassemia family, a normal blastocyst was transferred to the uterus and the accuracy of PGT-M was confirmed by amniocentesis at 16 weeks of gestation.
Conclusions: Our results suggest that HLRS can be applied for PGT-M of monogenic disorders or de novo mutations where the mutations haplotype cannot be determined due to absence of affected relatives.

Mouse Anti Human Cd163 Monoclonal Antibody

CABT-47162MH 25 µg
EUR 446.4

Mouse Anti Human Cd163 Monoclonal Antibody

CABT-47163MH 0.2 mg
EUR 1057.2

PE anti-human CD163

E16FHP163-025 25 tests
EUR 433.33
Description: Available in various conjugation types.

PE anti-human CD163

E16FHP163-100 100 tests
EUR 953.33
Description: Available in various conjugation types.

Anti-Human CD163 Antibody

101-M291 100 µg
EUR 399
Description: CD163, also known as hemoglobin scavenger receptor, is a type I transmembrane protein expressed exclusively in monocytes and macrophages. It is a scavenger receptor cysteine-rich superfamily (SRCR-SF) protein that contains nine SRCR motifs in its extracellular region. Two alternatively spliced cytoplasmic variants of human CD163 exist. A soluble form of CD163 can also be released by metalloproteinase-mediated shedding of the extracellular domain. CD163 mediates the endocytosis of haptoglobin-hemoglobin complexes.

APC anti-human CD163

E16FHA163-025 25 tests
EUR 520
Description: Available in various conjugation types.

APC anti-human CD163

E16FHA163-100 100 tests
EUR 1191.67
Description: Available in various conjugation types.

FITC anti-human CD163

E16FHF163-025 25 tests
EUR 520
Description: Available in various conjugation types.

FITC anti-human CD163

E16FHF163-100 100 tests
EUR 1191.67
Description: Available in various conjugation types.

Biotin anti-human CD163

E16FHB163-025U 25 μg
EUR 346.67
Description: Available in various conjugation types.

Biotin anti-human CD163

E16FHB163-100U 100 μg
EUR 780
Description: Available in various conjugation types.

Purified anti-human CD163

E16FHU163-100U 100 μg
EUR 433.33
Description: Available in various conjugation types.

CD163 (untagged)-Human CD163 molecule (CD163), transcript variant 1

SC117495 10 µg Ask for price

CD163 (untagged)-Human CD163 molecule (CD163), transcript variant 2

SC308167 10 µg Ask for price

CD163 (GFP-tagged) - Human CD163 molecule (CD163), transcript variant 2

RG212754 10 µg Ask for price

CD163 (GFP-tagged) - Human CD163 molecule (CD163), transcript variant 1

RG208557 10 µg Ask for price

Rabbit Anti Human CD163 Monoclonal Clone ABCC-3

IRBAHUCD163ABCC3C100UL each
EUR 496
Description: Rabbit Anti Human CD163 Monoclonal Clone ABCC-3

Recombinant Human CD163/CD163 Protein, His Tag

E40KMH346 20ug
EUR 495

PE-Cy7 anti-human CD163

E16FHN163-025 25 tests
EUR 650
Description: Available in various conjugation types.

PE-Cy7 anti-human CD163

E16FHN163-100 100 tests
EUR 1408.33
Description: Available in various conjugation types.

APC-Cy7 anti-human CD163

E16FHO163-025 25 tests
EUR 650
Description: Available in various conjugation types.

APC-Cy7 anti-human CD163

E16FHO163-100 100 tests
EUR 1408.33
Description: Available in various conjugation types.

CD163 (Myc-DDK-tagged)-Human CD163 molecule (CD163), transcript variant 1

RC208557 10 µg Ask for price

CD163 (Myc-DDK-tagged)-Human CD163 molecule (CD163), transcript variant 2

RC212754 10 µg Ask for price

PerCP-Cy5.5 anti-human CD163

E16FHS163-025 25 tests
EUR 541.67
Description: Available in various conjugation types.

PerCP-Cy5.5 anti-human CD163

E16FHS163-100 100 tests
EUR 1278.33
Description: Available in various conjugation types.

Mouse Monoclonal anti-human CD163

hAP-0161 100ug
EUR 250

Mouse Monoclonal anti-human CD163

hAP-0161A 50ug
EUR 400

Human CD163 Protein

E40KMPH6242 20ug
EUR 495

anti- CD163/M130 Antibody

FNab09771 100µg
EUR 658.5
Description: Antibody raised against CD163/M130 

Anti-Hu CD163 PE

1P-645-T025 25 tests
EUR 121

Anti-Hu CD163 PE

1P-645-T100 100 tests
EUR 242

Anti-Hu CD163 APC

1A-645-T025 25 tests
EUR 121

Anti-Hu CD163 APC

1A-645-T100 100 tests
EUR 242

Anti-Hu CD163 Purified

11-645-C025 0.025 mg
EUR 71.5

Anti-Hu CD163 Purified

11-645-C100 0.1 mg
EUR 143

Human CD163, Fc Tag

E24PHA282 50 μg
EUR 250

Human CD163, His Tag

E24PHA281 50 μg
EUR 250

Mouse Monoclonal anti-Human CD163 Antibody

xAP-0134 100ug
EUR 280

Mouse Monoclonal anti-Human CD163 Antibody

xAP-0135 100ug
EUR 280

Human CD163 ELISA Kit

ELA-E1726h 96 Tests
EUR 988.8

Human CD163 ELISA Kit

EK5296 96 tests
EUR 599

Human CD163 ELISA Kit

GWB-SKR207 96 Tests Ask for price

Human CD163 ELISA Kit

LF-EK50890 1×96T
EUR 777.6

Human CD163 shRNA Plasmid

20-abx956176
  • Ask for price
  • Ask for price
  • 150 µg
  • 300 µg

CD163 Antigen (CD163) Rabbit anti-Human Polyclonal (N-Terminus) (K20-T) Antibody

GWB-B1E200 0.05 ml Ask for price

CD163 (Human) ELISA Kit

EKA52023-5x96T 5x96T Ask for price

CD163 (Human) ELISA Kit

EKA52023-96T 96T
EUR 446.9

Recombinant Human CD163 Protein

RP02295 500μg
EUR 1625

PE Anti-human CD163 Antibody *GHI/61*

116301K0 25 tests
EUR 391
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PE Anti-human CD163 Antibody *GHI/61*

116301K0-25tests 25 tests
EUR 383
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PE Anti-human CD163 Antibody *GHI/61*

116301K1 100 tests
EUR 1015
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PE Anti-human CD163 Antibody *GHI/61*

116301K1-100tests 100 tests
EUR 995
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PE Anti-human CD163 Antibody *GHI/61*

116301K2 500 tests
EUR 3044
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PE Anti-human CD163 Antibody *GHI/61*

116301K2-500tests 500 tests
EUR 2984
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

Human CellExp? CD163, Human recombinant

9226-10 each
EUR 366

Human CellExp? CD163, Human recombinant

9226-50 each
EUR 927.6

APC Anti-human CD163 Antibody *GHI/61*

116301B0 25 tests
EUR 391
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

APC Anti-human CD163 Antibody *GHI/61*

116301B0-25tests 25 tests
EUR 383
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

APC Anti-human CD163 Antibody *GHI/61*

116301B1 100 tests
EUR 1015
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

APC Anti-human CD163 Antibody *GHI/61*

116301B1-100tests 100 tests
EUR 995
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

APC Anti-human CD163 Antibody *GHI/61*

116301B2 500 tests
EUR 3044
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

APC Anti-human CD163 Antibody *GHI/61*

116301B2-500tests 500 tests
EUR 2984
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

Alexa Fluor® 647 anti-human CD163

E16FHK163-025 25 tests
EUR 433.33
Description: Available in various conjugation types.

Alexa Fluor® 647 anti-human CD163

E16FHK163-100 100 tests
EUR 975
Description: Available in various conjugation types.

FITC Anti-human CD163 Antibody *GHI/61*

116301G0 100 tests
EUR 558
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

FITC Anti-human CD163 Antibody *GHI/61*

116301G0-100tests 100 tests
EUR 547
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

FITC Anti-human CD163 Antibody *GHI/61*

116301G1 500 tests
EUR 2093
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

FITC Anti-human CD163 Antibody *GHI/61*

116301G1-500tests 500 tests
EUR 2051
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

TRITC Anti-human CD163 Antibody *GHI/61*

116301H0 100 tests
EUR 558
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

TRITC Anti-human CD163 Antibody *GHI/61*

116301H0-100tests 100 tests
EUR 547
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

TRITC Anti-human CD163 Antibody *GHI/61*

116301H1 500 tests
EUR 2093
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

TRITC Anti-human CD163 Antibody *GHI/61*

116301H1-500tests 500 tests
EUR 2051
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PerCP Anti-human CD163 Antibody *GHI/61*

116301S0 25 tests
EUR 391
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PerCP Anti-human CD163 Antibody *GHI/61*

116301S0-25tests 25 tests
EUR 383
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PerCP Anti-human CD163 Antibody *GHI/61*

116301S1 100 tests
EUR 1015
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PerCP Anti-human CD163 Antibody *GHI/61*

116301S1-100tests 100 tests
EUR 995
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PerCP Anti-human CD163 Antibody *GHI/61*

116301S2 500 tests
EUR 3044
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PerCP Anti-human CD163 Antibody *GHI/61*

116301S2-500tests 500 tests
EUR 2984
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PacBlue Anti-human CD163 Antibody *GHI/61*

116301I0 100 tests
EUR 558
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PacBlue Anti-human CD163 Antibody *GHI/61*

116301I0-100tests 100 tests
EUR 547
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PacBlue Anti-human CD163 Antibody *GHI/61*

116301I1 500 tests
EUR 2093
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PacBlue Anti-human CD163 Antibody *GHI/61*

116301I1-500tests 500 tests
EUR 2051
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

Purified Anti-human CD163 Antibody *GHI/61*

11630000 100 ug
EUR 373
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

Purified Anti-human CD163 Antibody *GHI/61*

11630000-100ug 100 ug
EUR 365
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PacOrange Anti-human CD163 Antibody *GHI/61*

116301J0 100 tests
EUR 558
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PacOrange Anti-human CD163 Antibody *GHI/61*

116301J0-100tests 100 tests
EUR 547
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PacOrange Anti-human CD163 Antibody *GHI/61*

116301J1 500 tests
EUR 2093
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PacOrange Anti-human CD163 Antibody *GHI/61*

116301J1-500tests 500 tests
EUR 2051
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

Mouse Anti-Human CD163 Purified (100 ug)

TA320238 100 µg Ask for price

Human CD163 Protein, His Tag

CD3-H52E8 1mg
EUR 374.5
Description: Human CD163, His Tag (CD3-H52E8) is expressed from human 293 cells (HEK293). It contains AA Ser 42 - Ser 1045 (Accession # Q86VB7).

Human CD163 PicoKine ELISA Kit

EK0715 96 wells
EUR 510
Description: For quantitative detection of human CD163 in cell culture supernates, serum and plasma(heparin).

Human CD163 knockout cell line

ABC-KH2671 1 vial Ask for price
Description: Human CD163 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human CD163 knockdown cell line

ABC-KD2671 1 vial Ask for price
Description: Human CD163 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

Human CD163 Protein Lysate 20ug

IHUCD163PLLY20UG each
EUR 213
Description: Human CD163 Protein Lysate 20ug

Mouse Recombinant anti-Human CD163 Recombinant Antibody

xAP-0136 100ug
EUR 280

CD163 ORF Vector (Human) (pORF)

ORF017045 1.0 ug DNA
EUR 486

Canine CD163 antigen(CD163 LISA kit

GA-E0062CN-48T 48T
EUR 482.4

Canine CD163 antigen(CD163 LISA kit

GA-E0062CN-96T 96T
EUR 820.8

Porcine CD163 antigen,CD163 LISA kit

GA-E0045PC-48T 48T
EUR 436.8

Porcine CD163 antigen,CD163 LISA kit

GA-E0045PC-96T 96T
EUR 708

Porcine CD163 antigen, CD163 LISA kit

KLP0040 1 x 96 wells
EUR 341

Porcine CD163 antigen,CD163 LISA kit

YLA0139PO-48T 48T Ask for price

Porcine CD163 antigen,CD163 LISA kit

YLA0139PO-96T 96T Ask for price

Rat CD163 antigen, CD163 GENLISA ELISA

KLR2081 1 x 96 wells
EUR 341

Cd163 (untagged) - Mouse CD163 antigen (Cd163), transcript variant 2, (10ug)

MC223654 10 µg Ask for price

Cd163 (untagged) - Mouse CD163 antigen (Cd163), transcript variant 1, (10ug)

MC223773 10 µg Ask for price

CD163 ELISA Kit (Human) (OKCD07621)

OKCD07621 96 Wells
EUR 1123.2
Description: Description of target: The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: < 0.273ng/mL

CD163 ELISA Kit (Human) (OKAN04666)

OKAN04666 96 Wells
EUR 950.4
Description: Description of target: The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.273 ng/mL

CD163 ELISA Kit (Human) (OKBB00786)

OKBB00786 96 Wells
EUR 606
Description: Description of target: CD163(Cluster of Differentiation 163) is a human protein encoded by the CD163 gene. It has also been shown to mark cells of monocyte/macrophage lineage. CD163, a member of the scavenger receptor cysteine-rich(SRCR) superfamily, is exclusively expressed by monocytes and macrophages. Using FISH, somatic cell hybrid analysis, and radiation hybrid analysis, CD163 gene was mapped the to chromosome 12p13.3. CD163 is upregulated in a large range of diseases inflammatory diseases including type 2 diabetes, macrophage activation sickness, Tangier's disease, reumatoid arthritis etc.;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: <150pg/ml

CD163 ELISA Kit (Human) (OKBB01513)

OKBB01513 96 Wells
EUR 684
Description: Description of target: CD163(Cluster of Differentiation 163) is a human protein encoded by the CD163 gene. It has also been shown to mark cells of monocyte/macrophage lineage. CD163, a member of the scavenger receptor cysteine-rich(SRCR) superfamily, is exclusively expressed by monocytes and macrophages. Using FISH, somatic cell hybrid analysis, and radiation hybrid analysis, CD163 gene was mapped the to chromosome 12p13.3. CD163 is upregulated in a large range of diseases inflammatory diseases including type 2 diabetes, macrophage activation sickness, Tangier's disease, reumatoid arthritis etc.;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: <150pg/ml

PE/Cy5 Anti-human CD163 Antibody *GHI/61*

116301L0 25 tests
EUR 438
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PE/Cy5 Anti-human CD163 Antibody *GHI/61*

116301L0-25tests 25 tests
EUR 429
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PE/Cy5 Anti-human CD163 Antibody *GHI/61*

116301L1 100 tests
EUR 1140
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PE/Cy5 Anti-human CD163 Antibody *GHI/61*

116301L1-100tests 100 tests
EUR 1117
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PE/Cy5 Anti-human CD163 Antibody *GHI/61*

116301L2 500 tests
EUR 3419
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PE/Cy5 Anti-human CD163 Antibody *GHI/61*

116301L2-500tests 500 tests
EUR 3351
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PE/Cy7 Anti-human CD163 Antibody *GHI/61*

116301M0 25 tests
EUR 438
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PE/Cy7 Anti-human CD163 Antibody *GHI/61*

116301M0-25tests 25 tests
EUR 429
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PE/Cy7 Anti-human CD163 Antibody *GHI/61*

116301M1 100 tests
EUR 1140
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PE/Cy7 Anti-human CD163 Antibody *GHI/61*

116301M1-100tests 100 tests
EUR 1117
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PE/Cy7 Anti-human CD163 Antibody *GHI/61*

116301M2 500 tests
EUR 3419
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PE/Cy7 Anti-human CD163 Antibody *GHI/61*

116301M2-500tests 500 tests
EUR 3351
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

QuickDetect? CD163 (Human) ELISA Kit

K4422-100 each
EUR 966

APC/Cy7 Anti-human CD163 Antibody *GHI/61*

116301C0 25 tests
EUR 438
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

APC/Cy7 Anti-human CD163 Antibody *GHI/61*

116301C0-25tests 25 tests
EUR 429
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

APC/Cy7 Anti-human CD163 Antibody *GHI/61*

116301C1 100 tests
EUR 1140
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

APC/Cy7 Anti-human CD163 Antibody *GHI/61*

116301C1-100tests 100 tests
EUR 1117
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

APC/Cy7 Anti-human CD163 Antibody *GHI/61*

116301C2 500 tests
EUR 3419
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

APC/Cy7 Anti-human CD163 Antibody *GHI/61*

116301C2-500tests 500 tests
EUR 3351
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

Lenti ORF particles, CD163 (mGFP-tagged) - Human CD163 molecule (CD163), transcript variant 1, 200ul, >10^7 TU/mL

RC208557L2V 200 µl Ask for price

Lenti ORF particles, CD163 (mGFP-tagged) - Human CD163 molecule (CD163), transcript variant 1, 200ul, >10^7 TU/mL

RC208557L4V 200 µl Ask for price

PerCP/Cy5.5 Anti-human CD163 Antibody *GHI/61*

116301T0 25 tests
EUR 438
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PerCP/Cy5.5 Anti-human CD163 Antibody *GHI/61*

116301T0-25tests 25 tests
EUR 429
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PerCP/Cy5.5 Anti-human CD163 Antibody *GHI/61*

116301T1 100 tests
EUR 1140
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PerCP/Cy5.5 Anti-human CD163 Antibody *GHI/61*

116301T1-100tests 100 tests
EUR 1117
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PerCP/Cy5.5 Anti-human CD163 Antibody *GHI/61*

116301T2 500 tests
EUR 3419
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PerCP/Cy5.5 Anti-human CD163 Antibody *GHI/61*

116301T2-500tests 500 tests
EUR 3351
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

Anti-Hu CD163 PE-Cy™7

T7-645-T025 25 tests
EUR 137.5

Anti-Hu CD163 PE-Cy™7

T7-645-T100 100 tests
EUR 275

mFluorâ„¢ UV375 Anti-human CD163 Antibody *GHI/61*

116300X0 100 tests
EUR 558
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

mFluorâ„¢ UV375 Anti-human CD163 Antibody *GHI/61*

116300X1 500 tests
EUR 2093
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

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