A 2020 update on the use of genetic testing for patients

A 2020 update on the use of genetic testing for patients with primary immunodeficiency
- Introduction: Genetic testing of patients with clinically diagnosed or suspected primary immunodeficiencies (PIDs) constitutes standard of care. Choice of testing modality and patient attributes can impact the likelihood of securing a diagnosis.
- Areas covered: Published diagnostic rates for gene panel testing, exome sequencing (WES), and whole genome sequencing are compared among cohorts identified within PubMed. Performance of the testing platforms is reviewed in PIDs taken as a whole, followed by separate cohorts of patients with suspected PIDs, specific PIDs, and clinical phenotypes that can be associated with underlying PIDs.
- Expert opinion: Massively parallel high throughput sequencing clearly represents the most expedient method for diagnosis of PIDs. For patients from highly consanguineous backgrounds, WES and whole genome sequencing should be performed to obtain optimal diagnostic yield. For patients for whom familial consanguinity is unlikely, choice of platform depends upon the phenotype. In patients with suspected PIDs, assessment for copy number variants is important, whether as part of gene panel bioinformatic analyses or combined with WES.
- Diagnostic rates overall for massively parallel sequencing are high for clinically diagnosed and suspected PIDs. WES may have a slightly higher overall yield, but gene panel testing represents a cost effective and efficient reasonable initial step.

Mouse CXCL1/KC ELISA Kit |
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MBS9135758-5x96Tests | MyBiosource | 5x96Tests | EUR 2615 |
Mouse CXCL1/KC ELISA Kit |
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MBS9135758-96Tests | MyBiosource | 96Tests | EUR 570 |
Mouse CXCL1/KC ELISA Kit |
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RK00038 | Abclonal | 96 Tests | EUR 322.37 |
Recombinant Mouse KC/CXCL1 protein |
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CD00330-5ug | Jiaxing Korain Biotech Ltd (BT Labs) | 5ug | EUR 176 |
Description: Mouse CXCL1, also known as KC, is belonging to the CXC chemokine family. It is encoded by the GRO gene now designated CXCL1. The gene for CXCL1 was initially discovered in mouse fibroblasts by plateletderived growth factor. KC is member of the intercrine alpha (chemokine C-X-C) subfamily of chemokines. It is secreted by human melanoma cells, and also expressed by macrophages, neutrophils and epithelial cells. The functional receptor for CXCL1 has been identified as CXCR2. CXCL1 has chemotactic activity for neutrophils, and plays a role in inflammation and wound healing. Amino acid sequence of Mouse CXCL1 is approximately 60 % identical to the human CXCL1. KC was found to be involved in monocyte arrest on atherosclerotic endothelium and may also play a pathophysiological role in Alzheimer’s disease. |
Mouse KC (CXCL1) Recombinant Protein |
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M10-027 | ReliaTech | 20 µg | EUR 196.35 |
Description: All three isoforms of GRO or KC are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant murine KC is a 7.8 kDa protein consisting of 72 amino acids including the 'ELR' motif common to the CXC chemokine family that bind to CXCR1 or CXCR2. |
Mouse KC (CXCL1) Recombinant Protein |
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M10-027S | ReliaTech | 5 µg | EUR 92.4 |
Description: All three isoforms of GRO or KC are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant murine KC is a 7.8 kDa protein consisting of 72 amino acids including the 'ELR' motif common to the CXC chemokine family that bind to CXCR1 or CXCR2. |
Mouse CXCL1/KC Recombinant Protein |
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PROTP12850 | BosterBio | Regular: 20ug | EUR 265 |
Description: Mouse CXCL1/KC Recombinant Protein expressed in E. coli with His-tag. Sequence domain: 25-96aa. Application(s): SDS-PAGE. |
Recombinant Mouse GRO/KC (CXCL1) |
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7-01858 | CHI Scientific | 5µg | Ask for price |
Recombinant Mouse GRO/KC (CXCL1) |
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7-01859 | CHI Scientific | 20µg | Ask for price |
Recombinant Mouse GRO/KC (CXCL1) |
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7-01860 | CHI Scientific | 1mg | Ask for price |
Mouse GRO/KC (CXCL1), (Recombinant) |
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22060572-1 | Bio-WORLD | 5 µg | EUR 190.94 |
Recombinant Mouse GRO/KC (CXCL1) |
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MBS142042-0005mg | MyBiosource | 0.005mg | EUR 240 |
Recombinant Mouse GRO/KC (CXCL1) |
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MBS142042-002mg | MyBiosource | 0.02mg | EUR 310 |
Recombinant Mouse GRO/KC (CXCL1) |
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MBS142042-1mg | MyBiosource | 1mg | EUR 2880 |
Recombinant Mouse GRO/KC (CXCL1) |
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MBS142042-5x1mg | MyBiosource | 5x1mg | EUR 12630 |
GRO1/KC Mouse Recombinant (CXCL1) |
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rAP-0159 | Angio Proteomie | Inquiry | Ask for price |
Recombinant Mouse (E.Coli) GRO/KC (CXCL1) |
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RP-1037 | Alpha Diagnostics | 5 ug | EUR 196.8 |
GRO1/KC Mouse Recombinant Protein (CXCL1) |
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PROTP12850-1 | BosterBio | Regular: 20ug | EUR 380.4 |
Description: KC Mouse Recombinant also known as N51 and GRO1 produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 77 amino acids and having a molecular mass of approximately 8 kDa.;The GRO-1 is purified by proprietary chromatographic techniques. |
Recombinant Mouse Cxcl1/KC Protein, His Tag |
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E40MOP2119 | EnoGene | 20ug | EUR 495 |
KC (CXCL1) (AP) |
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MBS6484085-01mL | MyBiosource | 0.1mL | EUR 1100 |
KC (CXCL1) (AP) |
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MBS6484085-5x01mL | MyBiosource | 5x0.1mL | EUR 4810 |
KC (CXCL1) (PE) |
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MBS6484095-01mL | MyBiosource | 0.1mL | EUR 1100 |
KC (CXCL1) (PE) |
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MBS6484095-5x01mL | MyBiosource | 5x0.1mL | EUR 4810 |
KC (CXCL1) (APC) |
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MBS6484086-01mL | MyBiosource | 0.1mL | EUR 1100 |
KC (CXCL1) (APC) |
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MBS6484086-5x01mL | MyBiosource | 5x0.1mL | EUR 4810 |
KC (CXCL1) (HRP) |
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MBS6484089-01mL | MyBiosource | 0.1mL | EUR 1100 |
KC (CXCL1) (HRP) |
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MBS6484089-5x01mL | MyBiosource | 5x0.1mL | EUR 4810 |
KC (CXCL1) (FITC) |
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MBS6484088-01mL | MyBiosource | 0.1mL | EUR 1100 |
KC (CXCL1) (FITC) |
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MBS6484088-5x01mL | MyBiosource | 5x0.1mL | EUR 4810 |
Recombinant Mouse GRO/KC (CXCL1), His Tag |
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MBS144372-0005mg | MyBiosource | 0.005mg | EUR 240 |
Recombinant Mouse GRO/KC (CXCL1), His Tag |
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MBS144372-002mg | MyBiosource | 0.02mg | EUR 310 |
Recombinant Mouse GRO/KC (CXCL1), His Tag |
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MBS144372-1mg | MyBiosource | 1mg | EUR 3770 |
Recombinant Mouse GRO/KC (CXCL1), His Tag |
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MBS144372-5x1mg | MyBiosource | 5x1mg | EUR 16645 |
GRO/KC (CXCL1) Mouse Recombinant, His Tag |
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rAP-0149 | Angio Proteomie | Inquiry | Ask for price |
GRO-alpha, KC, CXCL1 (rMuKC), murine (mouse) |
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RC332-12 | Bio Basic | 5ug | EUR 125.26 |
KC (CXCL1) (Biotin) |
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MBS6484087-01mL | MyBiosource | 0.1mL | EUR 1100 |
KC (CXCL1) (Biotin) |
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MBS6484087-5x01mL | MyBiosource | 5x0.1mL | EUR 4810 |
KC (CXCL1) (Biotin) |
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MBS6003763-005mg | MyBiosource | 0.05(mg | EUR 810 |
KC (CXCL1) (Biotin) |
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MBS6003763-5x005mg | MyBiosource | 5x0.05mg | EUR 3490 |
RecombinantGRO-α/KC/CXCL1,Mouse(CHO-expressed) |
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BK0216 | Bioworld Biotech | 1mg | EUR 2200 |
Description: Active at 10 ng/ml, measured in a tube formation assay using HUVEC cells. |
Sunlong Medical™ Mouse CXCL1/KC ELISA Kit |
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EL0012Mo-48T | Sunlong | 48T | EUR 366 |
Sunlong Medical™ Mouse CXCL1/KC ELISA Kit |
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EL0012Mo-96T | Sunlong | 96T | EUR 455 |
CXCL1 (Gro, KC) (AP) |
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MBS6470964-01mL | MyBiosource | 0.1mL | EUR 1115 |
CXCL1 (Gro, KC) (AP) |
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MBS6470964-5x01mL | MyBiosource | 5x0.1mL | EUR 4875 |
CXCL1 (Gro, KC) (PE) |
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MBS6470974-01mL | MyBiosource | 0.1mL | EUR 1115 |
CXCL1 (Gro, KC) (PE) |
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MBS6470974-5x01mL | MyBiosource | 5x0.1mL | EUR 4875 |
CXCL1 (Gro, KC) (APC) |
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MBS6470965-01mL | MyBiosource | 0.1mL | EUR 1115 |
CXCL1 (Gro, KC) (APC) |
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MBS6470965-5x01mL | MyBiosource | 5x0.1mL | EUR 4875 |
CXCL1 (Gro, KC) (HRP) |
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MBS6470968-01mL | MyBiosource | 0.1mL | EUR 1115 |
CXCL1 (Gro, KC) (HRP) |
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MBS6470968-5x01mL | MyBiosource | 5x0.1mL | EUR 4875 |
Rat GRO/KC (CXCL1) |
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MBS691984-0005mg | MyBiosource | 0.005mg | EUR 300 |
Rat GRO/KC (CXCL1) |
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MBS691984-0025mg | MyBiosource | 0.025mg | EUR 450 |
Rat GRO/KC (CXCL1) |
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MBS691984-5x0025mg | MyBiosource | 5x0.025mg | EUR 1725 |
CXCL1 (Gro, KC) (FITC) |
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MBS6470967-01mL | MyBiosource | 0.1mL | EUR 1115 |
CXCL1 (Gro, KC) (FITC) |
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MBS6470967-5x01mL | MyBiosource | 5x0.1mL | EUR 4875 |
CXCL1 (Gro, KC) (Biotin) |
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MBS6470966-01mL | MyBiosource | 0.1mL | EUR 1115 |
CXCL1 (Gro, KC) (Biotin) |
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MBS6470966-5x01mL | MyBiosource | 5x0.1mL | EUR 4875 |
GRO / KC (CXCL1) Protein |
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abx260684-10g | Abbexa | 10 µg | EUR 325 |
GRO / KC (CXCL1) Protein |
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20-abx260684 | Abbexa |
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GRO / KC (CXCL1) Protein |
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abx260684-2g | Abbexa | 2 µg | EUR 225 |
GRO / KC (CXCL1) Protein |
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abx261870-10mg | Abbexa | 10 mg | EUR 325 |
GRO / KC (CXCL1) Protein |
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20-abx261870 | Abbexa |
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GRO / KC (CXCL1) Protein |
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abx261870-25mg | Abbexa | 25 mg | EUR 4625 |
GRO / KC (CXCL1) Protein |
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abx261870-5mg | Abbexa | 5 mg | EUR 225 |
KC (CXCL1) (MaxLight 405) |
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MBS6484090-01mL | MyBiosource | 0.1mL | EUR 1100 |
KC (CXCL1) (MaxLight 405) |
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MBS6484090-5x01mL | MyBiosource | 5x0.1mL | EUR 4810 |
KC (CXCL1) (MaxLight 490) |
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MBS6484091-01mL | MyBiosource | 0.1mL | EUR 1100 |
KC (CXCL1) (MaxLight 490) |
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MBS6484091-5x01mL | MyBiosource | 5x0.1mL | EUR 4810 |
KC (CXCL1) (MaxLight 550) |
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MBS6484092-01mL | MyBiosource | 0.1mL | EUR 1100 |
KC (CXCL1) (MaxLight 550) |
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MBS6484092-5x01mL | MyBiosource | 5x0.1mL | EUR 4810 |
KC (CXCL1) (MaxLight 650) |
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MBS6484093-01mL | MyBiosource | 0.1mL | EUR 1100 |
KC (CXCL1) (MaxLight 650) |
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MBS6484093-5x01mL | MyBiosource | 5x0.1mL | EUR 4810 |
KC (CXCL1) (MaxLight 750) |
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MBS6484094-01mL | MyBiosource | 0.1mL | EUR 1100 |
KC (CXCL1) (MaxLight 750) |
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MBS6484094-5x01mL | MyBiosource | 5x0.1mL | EUR 4810 |
RABBIT ANTI MOUSE CXCL1 |
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MBS221269-01mg | MyBiosource | 0.1mg | EUR 635 |
RABBIT ANTI MOUSE CXCL1 |
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MBS221269-5x01mg | MyBiosource | 5x0.1mg | EUR 2695 |
Recombinant Murine GRO/KC/ CXCL1 (rMuKC/CXCL1) |
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JOT-PR2018 | Jotbody | 5µg | EUR 205 |
Description: Measured by its ability to chemoattract human CXCR2 transfected BaF3 mouse proB cells. The ED50 for this effect is typically 3-15 ng/mL. |
Recombinant Murine GRO/KC/ CXCL1 (rMuKC/CXCL1) |
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PR2018 | Bioworld Biotech | 5µg | EUR 158 |
Description: Measured by its ability to chemoattract human CXCR2 transfected BaF3 mouse proB cells. The ED50 for this effect is typically 3-15 ng/mL. |
Mouse CXC-chemokine ligand 1,CXCL1;KC ELISA KIT |
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E1520Mo-1096T | Jiaxing Korain Biotech Ltd (BT Labs) | 10*96T | EUR 4122 |
Mouse CXC-chemokine ligand 1,CXCL1;KC ELISA KIT |
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E1520Mo-48wells | Jiaxing Korain Biotech Ltd (BT Labs) | 48 wells | EUR 300 |
Mouse CXC-chemokine ligand 1,CXCL1;KC ELISA KIT |
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E1520Mo-596T | Jiaxing Korain Biotech Ltd (BT Labs) | 5*96T | EUR 2061 |
Mouse CXC-chemokine ligand 1,CXCL1;KC ELISA KIT |
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E1520Mo-96wells | Jiaxing Korain Biotech Ltd (BT Labs) | 96 wells | EUR 458 |
Mouse CXC-chemokine ligand 1,CXCL1;KC ELISA KIT |
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JOT-EK1520Mo | Jotbody | 96 wells | Ask for price |
Description: Mouse |
Mouse CXC-chemokine ligand 1 (CXCL1/KC) ELISA Kit |
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MBS1601112-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 3955 |
Mouse CXC-chemokine ligand 1 (CXCL1/KC) ELISA Kit |
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MBS1601112-48StripWells | MyBiosource | 48-Strip-Wells | EUR 305 |
Mouse CXC-chemokine ligand 1 (CXCL1/KC) ELISA Kit |
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MBS1601112-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 2005 |
Mouse CXC-chemokine ligand 1 (CXCL1/KC) ELISA Kit |
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MBS1601112-96StripWells | MyBiosource | 96-Strip-Wells | EUR 475 |
Mouse CXC-chemokine ligand 1(CXCL1/KC)ELISA Kit |
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YLA0122MO-48T | Shanghai YL Biotech | 48T | Ask for price |
Mouse CXC-chemokine ligand 1(CXCL1/KC)ELISA Kit |
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YLA0122MO-96T | Shanghai YL Biotech | 96T | Ask for price |
Recombinant Murine KC/CXCL1 |
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AP60329 | SAB | 100ug | EUR 896 |
Recombinant Murine KC/CXCL1 |
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P1481-.005 | ApexBio | 5ug | EUR 108.8 |
Description: Peptides & Proteins|Recombinant Proteins |
Recombinant Murine KC/CXCL1 |
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P1481-.1 | ApexBio | 100ug | EUR 900 |
Description: Peptides & Proteins|Recombinant Proteins |
Recombinant Murine KC/CXCL1 |
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P1481-.5 | ApexBio | 500ug | EUR 2021.6 |
Description: Peptides & Proteins|Recombinant Proteins |
Mouse CXC-Chemokine ligand 1, CXCL1/KC GENLISA ELISA |
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KLM1520 | Krishgen | 1 x 96 wells | EUR 341 |
RABBIT ANTI MOUSE CXCL1:Biotin |
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MBS220128-005mg | MyBiosource | 0.05mg | EUR 635 |
RABBIT ANTI MOUSE CXCL1:Biotin |
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MBS220128-5x005mg | MyBiosource | 5x0.05mg | EUR 2680 |
Breast cancer (BRCA) genetesting in ovarian cancer
The discovery of cancer-causing BRCA1/2 mutations and the emergence of genetic testing have brought precision in patient selection for poly-(ADP)-ribose polymerase inhibitor (PARPi) treatment. Interestingly, patients who are carriers of BRCA1/2 mutations have a higher risk for developing cancer, but respond better to DNA-damaging cytotoxic therapy, such as platinum-based chemotherapy.
The distinctive biology of ovarian cancer involves high genomic instability consisting of gene amplification, gene deletion, oncogene hypomethylation, loss of heterozygosity, and tumor suppressor gene promoter hypermethylation in many of the DNA damage response (DDR) genes, including BRCA1/2. Several of these genetic abnormalities can impair high fidelity DNA damage repair increasing the therapeutic audience for PARPi’s. This is especially important given the clinical development over the last decade of this group of agents and the dramatic increase in progression free survival among ovarian cancer patients who received PARPi, both in treatment or maintenance setting. In this review, we summarize our current understanding of the role of BRCA1/2 mutations in ovarian cancer and present relevant clinical trials in which BRCA1/2 was investigated as biomarker for therapy. We also outline the role of homologous recombination (HR) deficiency as biomarker by presenting the recent clinical development and recent approvals PARPi for firstline maintenance in ovarian cancer.
Haplotyping by linked-read sequencing (HLRS) of the genetic disease carriers for preimplantation genetictesting without a proband or relatives
Background: In order to mitigate the risk of allele dropout (ADO) and ensure the accuracy of preimplantation genetic testing for monogenic disease (PGT-M), it is necessary to construct parental haplotypes. Typically, haplotype resolution is obtained by genotyping multiple polymorphic markers in both parents and a proband or a relative. Sometimes, single sperm typing, or tests on the polar bodies may also be useful. Nevertheless, this process is time-consuming. At present, there was no simple linkage analysis strategy for patients without affected relatives.
Method: To solve this problem, we established a haplotyping by linked-read sequencing (HLRS) method without the requirement for additional relatives. First, the haplotype of the genetic disease carriers in the family was constructed by linked-read sequencing, and then the informative single nucleotide polymorphisms (SNPs) in upstream and downstream mutation region were selected to construct the embryo haplotype and to determine whether the embryo was carrying the mutation. Two families were selected to validate this method; one with alpha thalassemia and the other with NDP gene disorder.
Results: The haplotyping by linked-read sequencing (HLRS) method was successfully applied to construct parental haplotypes without recruiting additional family members; the method was also validated for PGT-M. The mutation carriers in these families were sequenced by linked-read sequencing, and their haplotypes were successfully phased. Adjacent SNPs of the mutation gene were identified.
The informative SNPs were chosen for linkage analyses to identify the carrier embryos. For the alpha thalassemia family, a normal blastocyst was transferred to the uterus and the accuracy of PGT-M was confirmed by amniocentesis at 16 weeks of gestation.
Conclusions: Our results suggest that HLRS can be applied for PGT-M of monogenic disorders or de novo mutations where the mutations haplotype cannot be determined due to absence of affected relatives.
MOUSE ANTI HUMAN CD163: FITC |
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MBS225948-5x01mg | MyBiosource | 5x0.1mg | EUR 1785 |
Human CD163 antigen(CD163)ISA kit |
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GA-E0263HM-48T | GenAsia Biotech | 48T | EUR 346.8 |
Human CD163 antigen(CD163)ISA kit |
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GA-E0263HM-48Tests | GenAsia Biotech | 48 Tests | Ask for price |
Human CD163 antigen(CD163)ISA kit |
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GA-E0263HM-96T | GenAsia Biotech | 96T | EUR 559.2 |
Human CD163 antigen(CD163)ISA kit |
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GA-E0263HM-96Tests | GenAsia Biotech | 96 Tests | EUR 388 |
human CD163 antigen,CD163 LISA kit |
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201-12-0247 | Shanghai Sunred Biological Technology | 96 tests | EUR 528 |
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids. |
Human CD163 antigen,CD163 ELISA KIT |
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JOT-EK0246Hu | Jotbody | 96 wells | Ask for price |
Description: Human |
Human CD163 antigen,CD163 ELISA KIT |
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E0246Hu-1096T | Jiaxing Korain Biotech Ltd (BT Labs) | 10*96T | EUR 4122 |
Human CD163 antigen,CD163 ELISA KIT |
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E0246Hu-48wells | Jiaxing Korain Biotech Ltd (BT Labs) | 48 wells | EUR 300 |
Human CD163 antigen,CD163 ELISA KIT |
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E0246Hu-596T | Jiaxing Korain Biotech Ltd (BT Labs) | 5*96T | EUR 2061 |
Human CD163 antigen,CD163 ELISA KIT |
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E0246Hu-96wells | Jiaxing Korain Biotech Ltd (BT Labs) | 96 wells | EUR 458 |
Human CD163 antigen, CD163 ELISA Kit |
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MBS165165-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 3460 |
Human CD163 antigen, CD163 ELISA Kit |
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MBS165165-48StripWells | MyBiosource | 48-Strip-Wells | EUR 285 |
Human CD163 antigen, CD163 ELISA Kit |
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MBS165165-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 1750 |
Human CD163 antigen, CD163 ELISA Kit |
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MBS165165-96StripWells | MyBiosource | 96-Strip-Wells | EUR 425 |
Human CD163 Antigen (CD163) ELISA Kit |
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MBS9353075-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 6725 |
Human CD163 Antigen (CD163) ELISA Kit |
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MBS9353075-48StripWells | MyBiosource | 48-Strip-Wells | EUR 550 |
Human CD163 Antigen (CD163) ELISA Kit |
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MBS9353075-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 3420 |
Human CD163 Antigen (CD163) ELISA Kit |
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MBS9353075-96StripWells | MyBiosource | 96-Strip-Wells | EUR 765 |
human CD163 antigen,CD163 ELISA kit |
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YLA0098HU-48T | Shanghai YL Biotech | 48T | Ask for price |
human CD163 antigen,CD163 ELISA kit |
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YLA0098HU-96T | Shanghai YL Biotech | 96T | Ask for price |
Human CD163 Antigen, CD163 GENLISA ELISA |
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KBH0246 | Krishgen | 1 x 96 wells | EUR 286 |
Mouse Anti Human Cd163 Monoclonal Antibody |
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CABT-47162MH | Creative Diagnostics | 25 µg | EUR 322.14 |
Description: Mouse |
Mouse Anti Human Cd163 Monoclonal Antibody |
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CABT-47163MH | Creative Diagnostics | 0.2 mg | EUR 659.4 |
Description: Mouse |
Human CD163 antigen-CD163-ISA kit |
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QY-E05066 | Qayee Biotechnology | 96T | EUR 400 |
Mouse Anti Human CD163, APC Conjugated mAb |
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MBS9431893-100Tests | MyBiosource | 100Tests | EUR 520 |
Mouse Anti Human CD163, APC Conjugated mAb |
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MBS9431893-25Tests | MyBiosource | 25Tests | EUR 275 |
Mouse Anti Human CD163, APC Conjugated mAb |
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MBS9431893-5x100Tests | MyBiosource | 5x100Tests | EUR 2195 |
CD163 (untagged)-Human CD163 molecule (CD163), transcript variant 1 |
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SC117495 | Origene Technologies GmbH | 10 µg | Ask for price |
CD163 (untagged)-Human CD163 molecule (CD163), transcript variant 2 |
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SC308167 | Origene Technologies GmbH | 10 µg | Ask for price |
PE anti-human CD163 |
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E16FHP163-025 | EnoGene | 25 tests | EUR 433.33 |
Description: Available in various conjugation types. |
PE anti-human CD163 |
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E16FHP163-100 | EnoGene | 100 tests | EUR 953.33 |
Description: Available in various conjugation types. |
Anti-Human CD163 PE |
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MBS696987-100Tests | MyBiosource | 100Tests | EUR 415 |
Anti-Human CD163 PE |
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MBS696987-25Tests | MyBiosource | 25Tests | EUR 225 |
Anti-Human CD163 PE |
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MBS696987-5x100Tests | MyBiosource | 5x100Tests | EUR 1820 |
Anti-Human CD163 Antibody |
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101-M291 | ReliaTech | 100 µg | EUR 399 |
Description: CD163, also known as hemoglobin scavenger receptor, is a type I transmembrane protein expressed exclusively in monocytes and macrophages. It is a scavenger receptor cysteine-rich superfamily (SRCR-SF) protein that contains nine SRCR motifs in its extracellular region. Two alternatively spliced cytoplasmic variants of human CD163 exist. A soluble form of CD163 can also be released by metalloproteinase-mediated shedding of the extracellular domain. CD163 mediates the endocytosis of haptoglobin-hemoglobin complexes. |
APC anti-human CD163 |
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E16FHA163-025 | EnoGene | 25 tests | EUR 520 |
Description: Available in various conjugation types. |
APC anti-human CD163 |
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E16FHA163-100 | EnoGene | 100 tests | EUR 1191.67 |
Description: Available in various conjugation types. |
Anti-Human CD163 APC |
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MBS696989-100Tests | MyBiosource | 100Tests | EUR 480 |
Anti-Human CD163 APC |
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MBS696989-25Tests | MyBiosource | 25Tests | EUR 245 |
Anti-Human CD163 APC |
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MBS696989-5x100Tests | MyBiosource | 5x100Tests | EUR 2115 |
APC anti-human CD163 |
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MBS9459445-100Tests | MyBiosource | 100Tests | EUR 655 |
APC anti-human CD163 |
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MBS9459445-25Tests | MyBiosource | 25Tests | EUR 355 |
APC anti-human CD163 |
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MBS9459445-5x100Tests | MyBiosource | 5x100Tests | EUR 2790 |
FITC anti-human CD163 |
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E16FHF163-025 | EnoGene | 25 tests | EUR 520 |
Description: Available in various conjugation types. |
FITC anti-human CD163 |
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E16FHF163-100 | EnoGene | 100 tests | EUR 1191.67 |
Description: Available in various conjugation types. |
Biotin anti-human CD163 |
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E16FHB163-025U | EnoGene | 25 μg | EUR 346.67 |
Description: Available in various conjugation types. |
Biotin anti-human CD163 |
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E16FHB163-100U | EnoGene | 100 μg | EUR 780 |
Description: Available in various conjugation types. |
Purified anti-human CD163 |
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E16FHU163-100U | EnoGene | 100 μg | EUR 433.33 |
Description: Available in various conjugation types. |
CD163 (GFP-tagged) - Human CD163 molecule (CD163), transcript variant 2 |
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RG212754 | Origene Technologies GmbH | 10 µg | Ask for price |
CD163 (GFP-tagged) - Human CD163 molecule (CD163), transcript variant 1 |
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RG208557 | Origene Technologies GmbH | 10 µg | Ask for price |
Rabbit Anti Human CD163 Monoclonal Clone ABCC-3 |
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IRBAHUCD163ABCC3C100UL | Innovative research | each | EUR 496 |
Description: Rabbit Anti Human CD163 Monoclonal Clone ABCC-3 |
Recombinant Human CD163/CD163 Protein, His Tag |
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E40KMH346 | EnoGene | 20ug | EUR 495 |
Human CD163 siRNA |
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20-abx910931 | Abbexa |
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CD163 (Myc-DDK-tagged)-Human CD163 molecule (CD163), transcript variant 2 |
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RC212754 | Origene Technologies GmbH | 10 µg | Ask for price |
CD163 (Myc-DDK-tagged)-Human CD163 molecule (CD163), transcript variant 1 |
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RC208557 | Origene Technologies GmbH | 10 µg | Ask for price |
Human CD163 Protein |
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E40KMPH6242 | EnoGene | 20ug | EUR 495 |
Recombinant Human CD163 |
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MBS147285-0001mg | MyBiosource | 0.001mg | EUR 240 |
Recombinant Human CD163 |
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MBS147285-0005mg | MyBiosource | 0.005mg | EUR 310 |
Recombinant Human CD163 |
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MBS147285-005mg | MyBiosource | 0.05mg | EUR 1360 |
Recombinant Human CD163 |
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MBS147285-5x005mg | MyBiosource | 5x0.05mg | EUR 5800 |
CD163 siRNA (Human) |
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MBS8229683-15nmol | MyBiosource | 15nmol | EUR 405 |
CD163 siRNA (Human) |
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MBS8229683-30nmol | MyBiosource | 30nmol | EUR 565 |
CD163 siRNA (Human) |
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MBS8229683-5x30nmol | MyBiosource | 5x30nmol | EUR 2450 |
Anti-Human CD163 Antibody (M130) |
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MBS1564482-01mg | MyBiosource | 0.1mg | EUR 340 |
Anti-Human CD163 Antibody (M130) |
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MBS1564482-5x01mg | MyBiosource | 5x0.1mg | EUR 1235 |
Anti-Human CD163 Antibody (AB101) |
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MBS1570008-01mg | MyBiosource | 0.1mg | EUR 405 |
Anti-Human CD163 Antibody (AB101) |
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MBS1570008-5x01mg | MyBiosource | 5x0.1mg | EUR 1520 |
PE-Cy7 anti-human CD163 |
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E16FHN163-025 | EnoGene | 25 tests | EUR 650 |
Description: Available in various conjugation types. |
PE-Cy7 anti-human CD163 |
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E16FHN163-100 | EnoGene | 100 tests | EUR 1408.33 |
Description: Available in various conjugation types. |
APC-Cy7 anti-human CD163 |
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E16FHO163-025 | EnoGene | 25 tests | EUR 650 |
Description: Available in various conjugation types. |
APC-Cy7 anti-human CD163 |
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E16FHO163-100 | EnoGene | 100 tests | EUR 1408.33 |
Description: Available in various conjugation types. |
PerCP-Cy5.5 anti-human CD163 |
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E16FHS163-025 | EnoGene | 25 tests | EUR 541.67 |
Description: Available in various conjugation types. |
PerCP-Cy5.5 anti-human CD163 |
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E16FHS163-100 | EnoGene | 100 tests | EUR 1278.33 |
Description: Available in various conjugation types. |
Anti-Human CD163 PE-Cyanine7 |
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MBS696988-100Tests | MyBiosource | 100Tests | EUR 505 |
Anti-Human CD163 PE-Cyanine7 |
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MBS696988-25Tests | MyBiosource | 25Tests | EUR 270 |
Anti-Human CD163 PE-Cyanine7 |
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MBS696988-5x100Tests | MyBiosource | 5x100Tests | EUR 2220 |
Mouse Monoclonal anti-human CD163 |
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hAP-0161 | Angio Proteomie | 100ug | EUR 250 |
Mouse Monoclonal anti-human CD163 |
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hAP-0161A | Angio Proteomie | 50ug | EUR 400 |
Human CD163, Fc Tag |
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E24PHA282 | EnoGene | 50 μg | EUR 250 |
Human, Rat, Mouse CD163 antibody |
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P0405 | Omnimabs | 100ul | EUR 150 |
Human CD163, His Tag |
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E24PHA281 | EnoGene | 50 μg | EUR 250 |
Human CD163 ELISA Kit |
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GWB-SKR207 | GenWay Biotech | 96 Tests | Ask for price |
Human CD163 ELISA Kit |
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EK5296 | SAB | 96 tests | EUR 599 |
Human CD163 ELISA Kit |
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ELA-E1726h | Lifescience Market | 96 Tests | EUR 988.8 |
Human CD163 ELISA Kit |
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LF-EK50890 | Abfrontier | 1×96T | EUR 777.6 |
Human CD163 ELISA Kit |
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MBS3800092-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 6725 |
Human CD163 ELISA Kit |
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MBS3800092-48StripWells | MyBiosource | 48-Strip-Wells | EUR 550 |
Human CD163 ELISA Kit |
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MBS3800092-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 3420 |
Human CD163 ELISA Kit |
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MBS3800092-96StripWells | MyBiosource | 96-Strip-Wells | EUR 765 |
Human CD163 ELISA Kit |
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MBS824474-5x96Tests | MyBiosource | 5x96Tests | EUR 2880 |
Human CD163 ELISA Kit |
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MBS824474-96Tests | MyBiosource | 96Tests | EUR 645 |
Human CD163 shRNA Plasmid |
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20-abx956176 | Abbexa |
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Human CD163 Protein Lysate |
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MBS138999-002mg | MyBiosource | 0.02mg | EUR 365 |
Human CD163 Protein Lysate |
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MBS138999-5x002mg | MyBiosource | 5x0.02mg | EUR 1410 |
Human CD163 Recombinant Protein |
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PROTQ86VB7 | BosterBio | 10ug | EUR 350 |
Description: Human CD163 Recombinant Protein expressed in Baculovirus with His-tag. Sequence domain: 42-1050aa. Application(s): SDS-PAGE. Endotoxin: < 1 EU per 1ug of protein (determined by LAL method). |
Recombinant Human CD163 Protein |
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RP02295 | Abclonal | 500μg | EUR 244.43 |
CD163 (Human) ELISA Kit |
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EKA52023-5x96T | Biomatik Corporation | 5x96T | Ask for price |
CD163 (Human) ELISA Kit |
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EKA52023-96T | Biomatik Corporation | 96T | EUR 446.9 |
Human CellExp? CD163, Human recombinant |
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9226-10 | Biovision | each | EUR 366 |
Human CellExp? CD163, Human recombinant |
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9226-50 | Biovision | each | EUR 927.6 |
anti- CD163/M130 Antibody |
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FNab09771 | FN Test | 100µg | EUR 658.5 |
Description: Antibody raised against CD163/M130 |
Mouse Monoclonal anti-Human CD163 Antibody |
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xAP-0134 | Angio Proteomie | 100ug | EUR 280 |
Mouse Monoclonal anti-Human CD163 Antibody |
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xAP-0135 | Angio Proteomie | 100ug | EUR 280 |
CD163 Rabbit anti-Human Polyclonal Antibody |
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MBS2402782-005mL | MyBiosource | 0.05mL | EUR 615 |
CD163 Rabbit anti-Human Polyclonal Antibody |
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MBS2402782-5x005mL | MyBiosource | 5x0.05mL | EUR 2605 |
CD163 Rabbit anti-Human Polyclonal Antibody |
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MBS2403148-005mg | MyBiosource | 0.05mg | EUR 615 |
CD163 Rabbit anti-Human Polyclonal Antibody |
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MBS2403148-5x005mg | MyBiosource | 5x0.05mg | EUR 2605 |
Anti-Hu CD163 PE |
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1P-645-T025 | ExBio | 25 tests | EUR 121 |
Anti-Hu CD163 PE |
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1P-645-T100 | ExBio | 100 tests | EUR 242 |
Anti-Hu CD163 PE |
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MBS1800644-100Tests | MyBiosource | 100Tests | EUR 345 |
Anti-Hu CD163 PE |
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MBS1800644-5x100Tests | MyBiosource | 5x100Tests | EUR 1300 |
Anti-Hu CD163 APC |
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1A-645-T025 | ExBio | 25 tests | EUR 121 |
Anti-Hu CD163 APC |
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1A-645-T100 | ExBio | 100 tests | EUR 242 |
Anti-Hu CD163 APC |
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MBS1800643-100Tests | MyBiosource | 100Tests | EUR 345 |
Anti-Hu CD163 APC |
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MBS1800643-5x100Tests | MyBiosource | 5x100Tests | EUR 1300 |
MOUSE ANTI PIG CD163 |
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MBS224621-01mg | MyBiosource | 0.1mg | EUR 420 |
MOUSE ANTI PIG CD163 |
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MBS224621-5x01mg | MyBiosource | 5x0.1mg | EUR 1715 |
MOUSE ANTI RAT CD163 |
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MBS216354-01mg | MyBiosource | 0.1mg | EUR 455 |
MOUSE ANTI RAT CD163 |
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MBS216354-5x01mg | MyBiosource | 5x0.1mg | EUR 1885 |
MOUSE ANTI RAT CD163 |
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MBS216356-025mg | MyBiosource | 0.25mg | EUR 620 |
MOUSE ANTI RAT CD163 |
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MBS216356-5x025mg | MyBiosource | 5x0.25mg | EUR 2620 |
Anti-Hu CD163 Purified |
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11-645-C025 | ExBio | 0.025 mg | EUR 71.5 |
Anti-Hu CD163 Purified |
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11-645-C100 | ExBio | 0.1 mg | EUR 143 |
Anti-Hu CD163 Purified |
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MBS1800642-01mg | MyBiosource | 0.1mg | EUR 260 |
Anti-Hu CD163 Purified |
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MBS1800642-5x01mg | MyBiosource | 5x0.1mg | EUR 930 |
Human CD163 Protein, His Tag |
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CD3-H52E8 | ACROBIOSYSTEMS | 1mg | EUR 381.5 |
Description: Human CD163, His Tag (CD3-H52E8) is expressed from human 293 cells (HEK293). It contains AA Ser 42 - Ser 1045 (Accession # Q86VB7). |
CD163 Antigen (CD163) Rabbit anti-Human Polyclonal (N-Terminus) (K20-T) Antibody |
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GWB-B1E200 | GenWay Biotech | 0.05 ml | Ask for price |
Anti-Human CD163 (ABT-CD163) Mouse Monoclonal Antibody (Ready to Use) |
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MBS9511396-12mLRTU | MyBiosource | 12mL(RTU) | EUR 530 |
Anti-Human CD163 (ABT-CD163) Mouse Monoclonal Antibody (Ready to Use) |
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MBS9511396-3mLRTU | MyBiosource | 3mL(RTU) | EUR 240 |
Anti-Human CD163 (ABT-CD163) Mouse Monoclonal Antibody (Ready to Use) |
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MBS9511396-5x12mLRTU | MyBiosource | 5x12mL(RTU) | EUR 2230 |
Anti-Human CD163 (ABT-CD163) Mouse Monoclonal Antibody (Ready to Use) |
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MBS9511396-6mLRTU | MyBiosource | 6mL(RTU) | EUR 325 |
Human CD163 knockout cell line |
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ABC-KH2671 | AcceGen | 1 vial | Ask for price |
Description: Human CD163 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
Human CD163 PicoKine ELISA Kit |
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MBS176496-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 2755 |
Human CD163 PicoKine ELISA Kit |
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MBS176496-96StripWells | MyBiosource | 96-Strip-Wells | EUR 600 |
Human CD163 knockdown cell line |
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ABC-KD2671 | AcceGen | 1 vial | Ask for price |
Description: Human CD163 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest. |
Human CD163 Protein Lysate 20ug |
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IHUCD163PLLY20UG | Innovative research | each | EUR 213 |
Description: Human CD163 Protein Lysate 20ug |
Rabbit Polyclonal to Human CD163 |
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MBS245302-0125mL | MyBiosource | 0.125mL | EUR 620 |
Rabbit Polyclonal to Human CD163 |
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MBS245302-5x0125mL | MyBiosource | 5x0.125mL | EUR 2695 |
CD163 (NM_004244) Human Recombinant Protein |
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E45H38041M5 | EnoGene | 20 ug | EUR 785.42 |
CD163, Human, mAb RM3/1 |
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MBS584200-01mg | MyBiosource | 0.1mg | EUR 710 |
CD163, Human, mAb RM3/1 |
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MBS584200-05mg | MyBiosource | 0.5mg | EUR 1695 |