A 2020 update on the use of genetic testing for patients

Ivan September 9, 2020 0 Comments
myasthenickids

A 2020 update on the use of genetic testing for patients with primary immunodeficiency

  • Introduction: Genetic testing of patients with clinically diagnosed or suspected primary immunodeficiencies (PIDs) constitutes standard of care. Choice of testing modality and patient attributes can impact the likelihood of securing a diagnosis.
  • Areas covered: Published diagnostic rates for gene panel testing, exome sequencing (WES), and whole genome sequencing are compared among cohorts identified within PubMed. Performance of the testing platforms is reviewed in PIDs taken as a whole, followed by separate cohorts of patients with suspected PIDs, specific PIDs, and clinical phenotypes that can be associated with underlying PIDs.
  • Expert opinion: Massively parallel high throughput sequencing clearly represents the most expedient method for diagnosis of PIDs. For patients from highly consanguineous backgrounds, WES and whole genome sequencing should be performed to obtain optimal diagnostic yield. For patients for whom familial consanguinity is unlikely, choice of platform depends upon the phenotype. In patients with suspected PIDs, assessment for copy number variants is important, whether as part of gene panel bioinformatic analyses or combined with WES.
  • Diagnostic rates overall for massively parallel sequencing are high for clinically diagnosed and suspected PIDs. WES may have a slightly higher overall yield, but gene panel testing represents a cost effective and efficient reasonable initial step.
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GRO1/KC Mouse Recombinant Protein (CXCL1)
PROTP12850-1 Regular: 20ug
EUR 380.4
Description: KC Mouse Recombinant also known as N51 and GRO1 produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 77 amino acids and having a molecular mass of approximately 8 kDa.;The GRO-1 is purified by proprietary chromatographic techniques.

Recombinant Mouse (E.Coli) GRO/KC (CXCL1)
RP-1037 5 ug
EUR 196.8

GRO/KC (CXCL1), Rat Recombinant
P1288-25
EUR 444

GRO/KC (CXCL1), Rat Recombinant
P1288-5
EUR 210

Recombinant Murine KC (CXCL1) Protein
PROTP12850-2 20ug
EUR 380.4
Description: All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant murine KC is a 7.8 kDa protein consisting of 72 amino acids including the 'ELR' motif common to the CXC chemokine family that bind to CXCR1 or CXCR2.

GRO, KC, CXCL1, rRtGRO, rat
RC352-12 5ug
EUR 125.26

GRO1/KC Mouse, GRO/KC (CXCL1) Mouse Recombinant Protein, His Tag
PROTP12850 Regular: 20ug
EUR 380.4
Description: GRO1/KC Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 97 amino acids (25-96 a.a.) and having a molecular mass of 10.5kDa.;GRO1 is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

GRO-alpha, KC, CXCL1 (rMuKC), murine (mouse)
RC332-12 5ug
EUR 125.26

Recombinant Rat GRO/KC (CXCL1) Protein
PROTP14095-1 25ug
EUR 380.4
Description: All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant rat GRO/KC is a 7.8 kDa protein consisting of 72 amino acids including the 'ELR' motif common to the CXC chemokine family that bind to CXCR1 or CXCR2.

Rat CXCL1/CINC-1/KC ELISA Kit
RK00196 96 Tests
EUR 625.2

KC protein (Mouse)
30R-AK001 20 ug
EUR 327.6
Description: Purified recombinant Mouse KC protein

Anti-CXCL1 antibody
STJ28366 100 µl
EUR 332.4
Description: This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression of this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4.

Anti-CXCL1 antibody
STJ72026 100 µg
EUR 312

Rabbit Polyclonal antibody Anti-CRBN
Anti-CRBN 50 µg
EUR 418.8

KC antibody
70R-12297 100 ug
EUR 632.4
Description: Rabbit polyclonal KC antibody

KC antibody
70R-12298 100 ug
EUR 590.4
Description: Rabbit polyclonal KC antibody

KC Antibody
5211-100
EUR 451.2

KC Antibody
5212-100
EUR 470.4

KC Antibody
5212-30T
EUR 175.2

KC antibody
20R-1786 100 ug
EUR 781.2
Description: Rabbit polyclonal KC antibody

KC antibody
70R-KR006 50 ug
EUR 327.6
Description: Affinity purified Rabbit polyclonal KC antibody

Rabbit Anti Mouse Cxcl1 Polyclonal Antibody
CPBT-65100RM 0.1 mg
EUR 1057.2

anti-7-ketocholesterol (7-KC) (35A)
LF-MA90006 20 ug
EUR 1230
Description: Mouse monoclonal to 7-ketocholesterol (7-KC)

anti-7-ketocholesterol (7-KC) (35A)
LF-MA90007 100 ug
EUR 3270
Description: Mouse monoclonal to 7-ketocholesterol (7-KC)

KC Blocking Peptide
5212BP-50
EUR 183.6

KC Blocking Peptide
33R-11041 50 ug
EUR 229.2
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of KC antibody, catalog no. 70R-12298

KC Recombinant Protein
40-339-0005mg 0.005 mg
EUR 311.1
Description: All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant murine KC is a 7.8 kDa protein consisting of 72 amino acids including the 'ELR' motif common to the CXC chemokine family that bind to CXCR1 or CXCR2.

KC Recombinant Protein
40-339-002mg 0.02 mg
EUR 437.1
Description: All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant murine KC is a 7.8 kDa protein consisting of 72 amino acids including the 'ELR' motif common to the CXC chemokine family that bind to CXCR1 or CXCR2.

KC 12291 hydrochloride
B7332-10 10 mg
EUR 447.6

KC 12291 hydrochloride
B7332-50 50 mg
EUR 1635.6

Polyclonal KC Antibody
APR16969G 0.1mg
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human KC . This antibody is tested and proven to work in the following applications:

Anti-GRO alpha/Cxcl1 Antibody
A00533 100ug/vial
EUR 352.8

Anti-GRO alpha/CXCL1 Antibody
PA1760 100ug/vial
EUR 352.8

Mouse CXCL1 ELISA Kit
55R-1741 1 kit
EUR 748.8
Description: ELISA kit for detection of CXCL1 in the research laboratory

Mouse CXCL1 shRNA Plasmid
20-abx970673
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

GRO-alpha/CXCL1, Mouse
HY-P7188 50ug
EUR 639.6

KiloGreen 2X qPCR MasterMix-iCycler
MasterMix-KC 4 x 1.25 ml - 500 reactions (20 ul)
EUR 168

Mouse keinocyte chemoattractant (KC) ELISA kit
E03K0088-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Mouse keinocyte chemoattractant (KC) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse keinocyte chemoattractant (KC) ELISA kit
E03K0088-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Mouse keinocyte chemoattractant (KC) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse keinocyte chemoattractant (KC) ELISA kit
E03K0088-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Mouse keinocyte chemoattractant (KC) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

CXCL1 antibody
70R-10502 50 ug
EUR 560.4
Description: Affinity purified rabbit polyclonal CXCL1 antibody

CXCL1 Antibody
43679-100ul 100ul
EUR 302.4

CXCL1 antibody
70R-16681 50 ul
EUR 522
Description: Rabbit polyclonal CXCL1 antibody

CXCL1 antibody
70R-14297 100 ug
EUR 392.4
Description: Affinity purified Rabbit polyclonal CXCL1 antibody

CXCL1 antibody
70R-15473 100 ug
EUR 392.4
Description: Rabbit polyclonal CXCL1 antibody

CXCL1 protein
30R-3156 50 ug
EUR 308.4
Description: Purified recombinant CXCL1 protein

CXCL1 Peptide
42-129P 0.1 mg
EUR 405.6
Description: (CT) CXCL1 Peptide

CXCL1 Antibody
33054-100ul 100ul
EUR 302.4

CXCL1 siRNA
20-abx901350
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

CXCL1 siRNA
20-abx913248
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

CXCL1 siRNA
20-abx913249
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

Cxcl1 Antibody
1-CSB-PA09217A0Rb
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against Cxcl1. Recognizes Cxcl1 from Mouse. This antibody is Unconjugated. Tested in the following application: ELISA

CXCL1 Antibody
1-CSB-PA06097A0Rb
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against CXCL1. Recognizes CXCL1 from Human. This antibody is Unconjugated. Tested in the following application: ELISA

CXCL1 Antibody
1-CSB-PA006239GA01HU
  • EUR 716.40
  • EUR 399.60
  • 150ul
  • 50ul
Description: A polyclonal antibody against CXCL1. Recognizes CXCL1 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC

CXCL1 Antibody
1-CSB-PA009036
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against CXCL1. Recognizes CXCL1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: IHC, ELISA;IHC:1/100-1/300.ELISA:1/10000

CXCL1/GRO
EF012822 96 Tests
EUR 826.8

CXCL1/GRO
E21-597 10ug
EUR 411.6

pEGFP- CXCL1
PVT10178 2 ug
EUR 361.2

Polyclonal Goat anti-GST α-form
GST-ANTI-1 50 uL
EUR 336

Polyclonal Goat anti-GST μ-form
GST-ANTI-2 50 uL
EUR 336

Polyclonal Goat anti-GST p-form
GST-ANTI-3 50 uL
EUR 336

GRO/KC, murine recombinant
4210-100
EUR 927.6

GRO/KC, murine recombinant
4210-1000
EUR 4627.2

GRO/KC, murine recombinant
4210-20
EUR 307.2

Rabbit Anti Rat Cxcl1 Polyclonal Antibody
CPBT-65101RR 0.1 mg
EUR 1057.2

Mouse CXCL1 Detection Assay Kit
6725 1 kit
EUR 580.26
Description: Mouse CXCL1 Detection Assay Kit

CXCL1 protein (Mouse) (His tag)
80R-3368 50 ug
EUR 308.4
Description: Purified recombinant CXCL1 protein (Mouse) (His tag)

CXCL1 protein (Mouse) (His tag)
80R-3439 50 ug
EUR 308.4
Description: Purified recombinant CXCL1 protein (Mouse) (His tag)

CXCL1 ELISA Kit (Mouse) (OKBB00312)
OKBB00312 96 Tests
EUR 652.8
Description: Description of target: Chemokine (C-X-C motif) ligand 1 (CXCL1) is a small cytokine belonging to the CXC chemokine family that was previously called GRO1 oncogene, GROα, KC, Neutrophil-activating protein 3 (NAP-3) and melanoma growth stimulating activity, alpha (MSGA-α). In humans, this protein is encoded by the CXCL1 gene. The gene for CXCL1 is located on human chromosome 4 amongst genes for other CXC chemokines. The mature form of CXCL1 is maximally 73 amino acids long. CXCL1 is secreted by human melanoma cells, has mitogenic properties and is implicated in melanoma pathogenesis. CXCL1 is expressed by macrophages, neutrophils and epithelial cells, and has neutrophil chemoattractant activity. This chemokine elicits its effects by signaling through the chemokine receptor CXCR2.CXCL1 decreased the severity of multiple sclerosis and may offer a neuro-protective function. The standard product used in this kit is recombinant mouse CXCL1, consisting of 77 amino acids with the molecular mass of 8KDa.;Species reactivity: Mouse;Application: ELISA;Assay info: ;Sensitivity: < 1 pg/ml

Mouse CXCL1 PicoKine ELISA Kit
EK0723 96 wells
EUR 547.2
Description: For quantitative detection of mouse CXCL1 in cell culture supernates and serum.

CXCL1 ELISA Kit (Mouse) (OKAN04583)
OKAN04583 96 Wells
EUR 950.4
Description: Description of target: This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This secretory protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils. In mouse, deficiency of this gene is associated with colitis and with defects in immune cell recruitment to the lung.;Species reactivity: Mouse;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 6.0 pg/mL

CXCL1 ELISA Kit (Mouse) (OKCD05712)
OKCD05712 96 Wells
EUR 730.8
Description: Description of target: This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This secretory protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils. In mouse, deficiency of this gene is associated with colitis and with defects in immune cell recruitment to the lung.;Species reactivity: Mouse;Application: ELISA;Assay info: ;Sensitivity: < 6.0pg/mL

Cxcl1 ORF Vector (Mouse) (pORF)
ORF042286 1.0 ug DNA
EUR 114

ELISA kit for Mouse CXCL1
EK5299 96 tests
EUR 663.6
Description: Enzyme-linked immunosorbent assay kit for quantification of Mouse CXCL1 in samples from serum, plasma, tissue homogenates and other biological fluids.

Mouse CXCL1/GROα ELISA kit
LF-EK50473 1×96T
EUR 777.6

KC ELISA Kit (Mouse) : 96 Wells (OKAG00090)
OKAG00090 96 Wells
EUR 715.2
Description: Description of target: This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This secretory protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils. In mouse, deficiency of this gene is associated with colitis and with defects in immune cell recruitment to the lung.;Species reactivity: Mouse;Application: ELISA;Assay info: Quantitative Colorimentric Sandwich ELISA;Sensitivity: 8 pg/mL

CXCL1 antibody (HRP)
60R-2236 100 ug
EUR 392.4
Description: Rabbit polyclonal CXCL1 antibody (HRP)

CXCL1 antibody (FITC)
60R-2237 100 ug
EUR 392.4
Description: Rabbit polyclonal CXCL1 antibody (FITC)

CXCL1 antibody (biotin)
60R-2238 100 ug
EUR 392.4
Description: Rabbit polyclonal CXCL1 antibody (biotin)

CXCL1 Blocking Peptide
33R-7741 100 ug
EUR 216
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of CXCL1 antibody, catalog no. 70R-10502

CXCL1 Recombinant Protein
91-532 0.05 mg
EUR 714.3
Description: Chemokine (C-X-C motif) Ligand 1 Protein (CXCL1) is a growth factor for melanoma cells and a chemotaxin for neutrophils and a member of the CXC chemokine family that is a potent neutrophil attractant and activator and is also active toward basophils. CXCL1 is expressed by macrophages, neutrophils and epithelial cells; it has neutrophil chemoattractant activity. CXCL1 plays a critical nonredundant role in the development of experimental Lyme arthritis and carditis via CXCR2-mediated recruitment of neutrophils into the site of infection and may also have important pro-nociceptive effects via its direct actions on sensory neurons, and may induce long-term changes that involve protein synthesis.

CXCL1 Recombinant Protein
91-628 0.05 mg
EUR 651.3
Description: Cxcl1, also called Gro, Gro1, Mgsa or Scyb1, is short for growth-regulated alpha protein. The protein belongs to the intercrine alpha (chemokine CxC) family. The N-terminal processed form KC(5-72) of the protein is produced by proteolytic cleavage after secretion from bone marrow stromal cells, and shows a highly enhanced hematopoietic activity. Cxcl1 has chemotactic activity for neutrophils, and contributes to neutrophil activation during inflammation. Hematoregulatory chemokine, in vitro, suppresses hematopoietic progenitor cell proliferation.

CXCL1 Blocking Peptide
20-abx061039
  • EUR 343.20
  • EUR 510.00
  • 1 mg
  • 5 mg

Cxcl1 Polyclonal Antibody
A51950 100 µg
EUR 684.66
Description: fast delivery possible

CXCL1 Polyclonal Antibody
A51978 100 µg
EUR 684.66
Description: kits suitable for this type of research

CXCL1 Conjugated Antibody
C33054 100ul
EUR 476.4

CXCL1 cloning plasmid
CSB-CL006239HU-10ug 10ug
EUR 279.6
Description: A cloning plasmid for the CXCL1 gene.

Recombinant Human CXCL1
P0109 100ug
EUR 626.83
Description: Recombinant Human protein for CXCL1

Recombinant Human CXCL1
P0207 100ug
EUR 626.83
Description: Recombinant Human protein for CXCL1

pCMV-SPORT6-CXCL1
PVT13291 2 ug
EUR 469.2

Mouse CXCL1 AssayLite Antibody (FITC Conjugate)
70027-05141 150 ug
EUR 513.6

Mouse Growth-regulated alpha protein (Cxcl1)
1-CSB-RP092174m
  • EUR 606.00
  • EUR 318.00
  • EUR 2192.40
  • EUR 919.20
  • EUR 1461.60
  • EUR 402.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Mouse Growth-regulated alpha protein(Cxcl1),partial expressed in E.coli

Mouse CXCL1/GROα ELISA kit (4X96T)
LF-EK50474 4×96T
EUR 2641.2

GRO-alpha/CXCL1 (CHO-expressed), Mouse
HY-P7186 50ug
EUR 404.4

Cxcl1 sgRNA CRISPR Lentivector set (Mouse)
K4368201 3 x 1.0 ug
EUR 406.8

Goat keinocyte chemoattractant (KC) ELISA kit
E06K0088-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Goat keinocyte chemoattractant (KC) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Breast cancer (BRCA) genetesting in ovarian cancer

The discovery of cancer-causing BRCA1/2 mutations and the emergence of genetic testing have brought precision in patient selection for poly-(ADP)-ribose polymerase inhibitor (PARPi) treatment. Interestingly, patients who are carriers of BRCA1/2 mutations have a higher risk for developing cancer, but respond better to DNA-damaging cytotoxic therapy, such as platinum-based chemotherapy.
The distinctive biology of ovarian cancer involves high genomic instability consisting of gene amplification, gene deletion, oncogene hypomethylation, loss of heterozygosity, and tumor suppressor gene promoter hypermethylation in many of the DNA damage response (DDR) genes, including BRCA1/2. Several of these genetic abnormalities can impair high fidelity DNA damage repair increasing the therapeutic audience for PARPi’s. This is especially important given the clinical development over the last decade of this group of agents and the dramatic increase in progression free survival among ovarian cancer patients who received PARPi, both in treatment or maintenance setting. In this review, we summarize our current understanding of the role of BRCA1/2 mutations in ovarian cancer and present relevant clinical trials in which BRCA1/2 was investigated as biomarker for therapy. We also outline the role of homologous recombination (HR) deficiency as biomarker by presenting the recent clinical development and recent approvals PARPi for firstline maintenance in ovarian cancer.

Haplotyping by linked-read sequencing (HLRS) of the genetic disease carriers for preimplantation genetictesting without a proband or relatives

Background: In order to mitigate the risk of allele dropout (ADO) and ensure the accuracy of preimplantation genetic testing for monogenic disease (PGT-M), it is necessary to construct parental haplotypes. Typically, haplotype resolution is obtained by genotyping multiple polymorphic markers in both parents and a proband or a relative. Sometimes, single sperm typing, or tests on the polar bodies may also be useful. Nevertheless, this process is time-consuming. At present, there was no simple linkage analysis strategy for patients without affected relatives.
Method: To solve this problem, we established a haplotyping by linked-read sequencing (HLRS) method without the requirement for additional relatives. First, the haplotype of the genetic disease carriers in the family was constructed by linked-read sequencing, and then the informative single nucleotide polymorphisms (SNPs) in upstream and downstream mutation region were selected to construct the embryo haplotype and to determine whether the embryo was carrying the mutation. Two families were selected to validate this method; one with alpha thalassemia and the other with NDP gene disorder.
Results: The haplotyping by linked-read sequencing (HLRS) method was successfully applied to construct parental haplotypes without recruiting additional family members; the method was also validated for PGT-M. The mutation carriers in these families were sequenced by linked-read sequencing, and their haplotypes were successfully phased. Adjacent SNPs of the mutation gene were identified.
The informative SNPs were chosen for linkage analyses to identify the carrier embryos. For the alpha thalassemia family, a normal blastocyst was transferred to the uterus and the accuracy of PGT-M was confirmed by amniocentesis at 16 weeks of gestation.
Conclusions: Our results suggest that HLRS can be applied for PGT-M of monogenic disorders or de novo mutations where the mutations haplotype cannot be determined due to absence of affected relatives.

Anti-CD163
DB-045-0.5 500 μl
EUR 460.8
Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated

Anti-CD163
DB-045-1 1 ml
EUR 735.6
Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated

Anti-CD163
DB-045-RTU-15 15 ml
EUR 424.8
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-CD163
DB-045-RTU-7 7 ml
EUR 277.2
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-CD163
DB045RTU-15 15 ml
EUR 424.8
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-CD163
DB045RTU-7 7 ml
EUR 277.2
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Mouse Cluster Of Differentiation (CD163) ELISA Kit
DLR-CD163-Mu-48T 48T
EUR 609.6
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Cluster Of Differentiation (CD163) in samples from serum, plasma or other biological fluids.

Mouse Cluster Of Differentiation (CD163) ELISA Kit
DLR-CD163-Mu-96T 96T
EUR 793.2
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Cluster Of Differentiation (CD163) in samples from serum, plasma or other biological fluids.

Rat Cluster Of Differentiation (CD163) ELISA Kit
DLR-CD163-Ra-48T 48T
EUR 609.6
Description: A sandwich quantitative ELISA assay kit for detection of Rat Cluster Of Differentiation (CD163) in samples from serum, plasma, tissue homogenates or other biological fluids.

Rat Cluster Of Differentiation (CD163) ELISA Kit
DLR-CD163-Ra-96T 96T
EUR 793.2
Description: A sandwich quantitative ELISA assay kit for detection of Rat Cluster Of Differentiation (CD163) in samples from serum, plasma, tissue homogenates or other biological fluids.

Mouse Cluster Of Differentiation (CD163) ELISA Kit
RD-CD163-Mu-48Tests 48 Tests
EUR 613.2

Mouse Cluster Of Differentiation (CD163) ELISA Kit
RD-CD163-Mu-96Tests 96 Tests
EUR 850.8

Rat Cluster Of Differentiation (CD163) ELISA Kit
RD-CD163-Ra-48Tests 48 Tests
EUR 613.2

Rat Cluster Of Differentiation (CD163) ELISA Kit
RD-CD163-Ra-96Tests 96 Tests
EUR 850.8

Mouse Cluster Of Differentiation (CD163) ELISA Kit
RDR-CD163-Mu-48Tests 48 Tests
EUR 640.8

Mouse Cluster Of Differentiation (CD163) ELISA Kit
RDR-CD163-Mu-96Tests 96 Tests
EUR 890.4

Rat Cluster Of Differentiation (CD163) ELISA Kit
RDR-CD163-Ra-48Tests 48 Tests
EUR 640.8

Rat Cluster Of Differentiation (CD163) ELISA Kit
RDR-CD163-Ra-96Tests 96 Tests
EUR 890.4

Rabbit Polyclonal antibody Anti-CRBN
Anti-CRBN 50 µg
EUR 418.8

Anti-CD163 Antibody
A00812-1 100ug/vial
EUR 400.8

Anti-CD163 Antibody
PA1874 100ug/vial
EUR 352.8

Anti-CD163 Antibody
PA1874-1 100ug/vial
EUR 400.8

Anti-CD163 antibody
STJ110681 100 µl
EUR 332.4
Description: The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Anti-CD163 Antibody
STJ500423 100 µg
EUR 571.2

Anti-CD163 Antibody
STJ500424 100 µg
EUR 571.2

Anti-CD163 antibody
STJ160082 1 mL C
EUR 1129.2

Anti-CD163 antibody
STJ16100302 100 µg
EUR 864

Anti-CD163 antibody
STJ16100324 1 mL
EUR 1174.8

Anti-CD163 antibody
STJ180301 0.1 ml
EUR 258

Anti-CD163 antibody
STJ190009 200 µl
EUR 236.4
Description: Unconjugated Mouse monoclonal to CD163 (AS1A1)

Anti-Hu CD163 Purified
11-645-C025 0.025 mg
EUR 118.8

Anti-Hu CD163 Purified
11-645-C100 0.1 mg
EUR 189.6

Anti-CD163/M130 Antibody
A00812 100ul
EUR 476.4
Description: Rabbit IgG polyclonal antibody for Scavenger receptor cysteine-rich type 1 protein M130 (CD163) detection.tested for IF, IHC, WB in Human, Mouse, Rat. Various direct flourescent conjugates are available for FCM upon request. Please contact us for details.

Anti-Hu CD163 APC
1A-645-T025 25 tests
EUR 168

Anti-Hu CD163 APC
1A-645-T100 100 tests
EUR 288

Anti-Hu CD163 PE
1P-645-T025 25 tests
EUR 168

Anti-Hu CD163 PE
1P-645-T100 100 tests
EUR 288

Anti-CD163/M130 antibody
PAab09771 100 ug
EUR 426

anti- CD163/M130 Antibody
FNab09771 100µg
EUR 658.5
Description: Antibody raised against CD163/M130 

Anti-CD163 Antibody BIOTIN
STJ500425 100 µg
EUR 703.2

Anti-CD163 Antibody FITC
STJ500426 100 µg
EUR 703.2

Anti-CD163 Antibody BIOTIN
STJ500427 100 µg
EUR 703.2

Anti-CD163 Antibody FITC
STJ500428 100 µg
EUR 703.2

human CD163 antigen,CD163 LISA kit
201-12-0247 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human CD163 antigen(CD163)ISA kit
GA-E0263HM-48T 48T
EUR 346.8

Human CD163 antigen(CD163)ISA kit
GA-E0263HM-96T 96T
EUR 559.2

Human CD163 antigen(CD163)ISA kit
QY-E05066 96T
EUR 433.2

Mouse Anti Human Cd163 Monoclonal Antibody
CABT-47162MH 25 µg
EUR 446.4

Mouse Anti Human Cd163 Monoclonal Antibody
CABT-47163MH 0.2 mg
EUR 1057.2

Anti-CD163 Rabbit Monoclonal Antibody
M00812 100ug/vial
EUR 476.4
Description: Rabbit Monoclonal CD163 Antibody. Validated in IP, WB and tested in Human.

Anti-Hu CD163 PE-Cy7
T7-645-T025 25 tests
EUR 184.8

Anti-Hu CD163 PE-Cy7
T7-645-T100 100 tests
EUR 321.6

Anti-Hu CD163 PerCP-Cy5.5
T9-645-T025 25 tests
EUR 235.2

Anti-Hu CD163 PerCP-Cy5.5
T9-645-T100 100 tests
EUR 422.4

Polyclonal Goat anti-GST α-form
GST-ANTI-1 50 uL
EUR 336

Polyclonal Goat anti-GST μ-form
GST-ANTI-2 50 uL
EUR 336

Polyclonal Goat anti-GST p-form
GST-ANTI-3 50 uL
EUR 336

Porcine CD163 antigen,CD163 LISA kit
GA-E0045PC-48T 48T
EUR 436.8

Porcine CD163 antigen,CD163 LISA kit
GA-E0045PC-96T 96T
EUR 708

Canine CD163 antigen(CD163 LISA kit
GA-E0062CN-48T 48T
EUR 482.4

Canine CD163 antigen(CD163 LISA kit
GA-E0062CN-96T 96T
EUR 820.8

CD163 Antibody
49553-100ul 100ul
EUR 399.6

CD163 Antibody
49553-50ul 50ul
EUR 286.8

CD163 Antibody
37157-100ul 100ul
EUR 302.4

CD163 antibody
10R-6496 100 ug
EUR 243.6
Description: Mouse monoclonal CD163 antibody

CD163 antibody
10R-CD163aRT 250 ug
EUR 859.2
Description: Mouse monoclonal CD163 antibody

CD163 Antibody
ABD8235 100 ug
EUR 525.6

CD163 Antibody
20-abx242956
  • EUR 560.40
  • EUR 393.60
  • 100 ul
  • 50 ul

CD163 siRNA
20-abx910930
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

CD163 siRNA
20-abx910931
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

CD163 Antibody
1-CSB-PA801238LA01HU
  • EUR 380.40
  • EUR 402.00
  • 100ul
  • 50ul
Description: A polyclonal antibody against CD163. Recognizes CD163 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IF; Recommended dilution: IF:1:50-1:200

Cd163 Antibody
1-CSB-PA650452LA01MO
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against Cd163. Recognizes Cd163 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB; Recommended dilution: WB:1:500-1:2000

CD163 Antibody
1-CSB-PA969205
  • EUR 380.40
  • EUR 292.80
  • 100ul
  • 50ul
Description: A polyclonal antibody against CD163. Recognizes CD163 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:1000-1:2000, IHC:1:25-1:100

CD163 Antibody
DF8235 200ul
EUR 420

Mouse Anti Rat Cd163 Monoclonal Antibody
DMABT-47170MR 0.25 mg
EUR 889.2

Mouse Anti Rat Cd163 Monoclonal Antibody
DMABT-47171MR 0.1 mg
EUR 670.8

Human CD163 shRNA Plasmid
20-abx956176
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

Human CD163 ELISA Kit
LF-EK50890 1×96T
EUR 777.6

Human CD163 ELISA Kit
ELA-E1726h 96 Tests
EUR 988.8

Anti-Human CD163 DyLight® 488 conjugated Antibody
A00812-Dyl488 100ug/vial
EUR 412.8

Anti-Human CD163 DyLight® 550 conjugated Antibody
A00812-Dyl550 100ug/vial
EUR 412.8

Mouse Anti-Human CD163 monoclonal antibody, clone JID274
CABT-L2938-100uL500uL 100 uL, 500 uL
EUR 602.4

Human CellExp? CD163, Human recombinant
9226-10
EUR 366

Human CellExp? CD163, Human recombinant
9226-50
EUR 927.6

Mouse Anti Pig Cd163 Monoclonal Antibody,FITC
CABT-47164MP 0.1 mg
EUR 1057.2

Mouse Anti Pig Cd163 Monoclonal Antibody,RPE
CABT-47166MP 100 TEST
EUR 858

Mouse Anti Rat Cd163 Monoclonal Antibody,Biotin
DMABT-47168MR 0.1 mg
EUR 1057.2

Mouse Anti Rat Cd163 Monoclonal Antibody,FITC
DMABT-47169MR 0.1 mg
EUR 1057.2

Mouse Anti Rat Cd163 Monoclonal Antibody,RPE
DMABT-47172MR 100 TEST
EUR 1070.4

Anti-CD163 Rabbit Monoclonal Antibody, Clone#RM371
M00812-1 100uL
EUR 462
Description: Anti-CD163 Rabbit Monoclonal Antibody, Clone#RM371 tested in WB, IHC, reactive to Human

CD163 antibody (PE)
61R-1319 100 tests
EUR 483.6
Description: Mouse monoclonal CD163 antibody (PE)

CD163 antibody (biotin)
61R-1569 100 ug
EUR 418.8
Description: Mouse monoclonal CD163 antibody (biotin)

CD163 antibody (biotin)
61R-CD163BHUBT 100 ug
EUR 1105.2
Description: Mouse monoclonal CD163 antibody (biotin)

CD163 antibody (biotin)
61R-CD163CHUBT 250 ug
EUR 937.2
Description: Mouse monoclonal CD163 antibody (biotin)

Recombinant Porcine CD163
7-04750 10µg Ask for price

Recombinant Porcine CD163
7-04751 50µg Ask for price

Recombinant Porcine CD163
7-04752 1mg Ask for price

Cd163 Polyclonal Antibody
A53832 100 µg
EUR 684.66
Description: Ask the seller for details

CD163 Rabbit pAb
A8383-100ul 100 ul
EUR 369.6

CD163 Rabbit pAb
A8383-200ul 200 ul
EUR 550.8

CD163 Rabbit pAb
A8383-20ul 20 ul
EUR 219.6

CD163 Rabbit pAb
A8383-50ul 50 ul
EUR 267.6

Porcine CD163 Protein
20-abx260472
  • EUR 276.00
  • EUR 2798.40
  • EUR 393.60
  • 10 ug
  • 1 mg
  • 50 ug

CD163 Recombinant Protein
96-843 0.1 mg
EUR 714.3
Description: Scavenger receptor cysteine-rich type 1 protein M130 (CD163) is also known as hemoglobin scavenger receptor, which is a scavenger receptor for the hemoglobin-haptoglobin complex. CD163 has also been shown to mark cells of monocyte/macrophage lineage. A soluble form of the receptor exists in plasma, commonly denoted sCD163. sCD163 is generated by ectodomain shedding of the membrane bound receptor. sCD163 is upregulated in a large range of inflammatory diseases including liver cirrhosis, type 2 diabetes, macrophage activation syndrome, Gaucher's disease, sepsis, HIV infection, rheumatoid arthritis and Hodgkin Lymphoma.

CD163 Conjugated Antibody
C37157 100ul
EUR 476.4

CD163 Conjugated Antibody
C49553 100ul
EUR 476.4

CD163 Blocking Peptide
DF8235-BP 1mg
EUR 234

CD163 ELISA Kit (Human) (OKBB00786)
OKBB00786 96 Wells
EUR 606
Description: Description of target: CD163(Cluster of Differentiation 163) is a human protein encoded by the CD163 gene. It has also been shown to mark cells of monocyte/macrophage lineage. CD163, a member of the scavenger receptor cysteine-rich(SRCR) superfamily, is exclusively expressed by monocytes and macrophages. Using FISH, somatic cell hybrid analysis, and radiation hybrid analysis, CD163 gene was mapped the to chromosome 12p13.3. CD163 is upregulated in a large range of diseases inflammatory diseases including type 2 diabetes, macrophage activation sickness, Tangier's disease, reumatoid arthritis etc.;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: <150pg/ml

CD163 ELISA Kit (Human) (OKBB01513)
OKBB01513 96 Wells
EUR 684
Description: Description of target: CD163(Cluster of Differentiation 163) is a human protein encoded by the CD163 gene. It has also been shown to mark cells of monocyte/macrophage lineage. CD163, a member of the scavenger receptor cysteine-rich(SRCR) superfamily, is exclusively expressed by monocytes and macrophages. Using FISH, somatic cell hybrid analysis, and radiation hybrid analysis, CD163 gene was mapped the to chromosome 12p13.3. CD163 is upregulated in a large range of diseases inflammatory diseases including type 2 diabetes, macrophage activation sickness, Tangier's disease, reumatoid arthritis etc.;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: <150pg/ml

Human CD163 PicoKine ELISA Kit
EK0715 96 wells
EUR 510
Description: For quantitative detection of human CD163 in cell culture supernates, serum and plasma(heparin).

CD163 ELISA Kit (Human) (OKAN04666)
OKAN04666 96 Wells
EUR 950.4
Description: Description of target: The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.273 ng/mL

CD163 ORF Vector (Human) (pORF)
ORF017045 1.0 ug DNA
EUR 486

ELISA kit for Human CD163
EK5296 96 tests
EUR 663.6
Description: Enzyme-linked immunosorbent assay kit for quantification of Human CD163 in samples from serum, plasma, tissue homogenates and other biological fluids.

QuickDetect? CD163 (Human) ELISA Kit
K4422-100
EUR 966

CD163 ELISA Kit (Human) (OKCD07621)
OKCD07621 96 Wells
EUR 1123.2
Description: Description of target: The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: < 0.273ng/mL

Human soluble CD163(sCD163) ELISA Kit
CSB-E14050h-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Human soluble CD163 (sCD163) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human soluble CD163(sCD163) ELISA Kit
1-CSB-E14050h
  • EUR 952.80
  • EUR 6033.60
  • EUR 3200.40
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Human soluble CD163(sCD163) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

CD163 sgRNA CRISPR Lentivector set (Human)
K0405601 3 x 1.0 ug
EUR 406.8

CD163 Monoclonal Antibody [RMC238A]
A68443 100 µl
EUR 754.26
Description: Ask the seller for details

CD163(M130/1240) Antibody
BNC041240-100 100uL
EUR 238.8
Description: Primary antibody against CD163(M130/1240), CF405S conjugate, Concentration: 0.1mg/mL

CD163(M130/1240) Antibody
BNC041240-500 500uL
EUR 652.8
Description: Primary antibody against CD163(M130/1240), CF405S conjugate, Concentration: 0.1mg/mL

CD163 Antibody, HRP conjugated
1-CSB-PA801238LB01HU
  • EUR 380.40
  • EUR 402.00
  • 100ul
  • 50ul
Description: A polyclonal antibody against CD163. Recognizes CD163 from Human. This antibody is HRP conjugated. Tested in the following application: ELISA

CD163 Antibody, FITC conjugated
1-CSB-PA801238LC01HU
  • EUR 380.40
  • EUR 402.00
  • 100ul
  • 50ul
Description: A polyclonal antibody against CD163. Recognizes CD163 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

CD163 Antibody, Biotin conjugated
1-CSB-PA801238LD01HU
  • EUR 380.40
  • EUR 402.00
  • 100ul
  • 50ul
Description: A polyclonal antibody against CD163. Recognizes CD163 from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA

Cd163 Antibody, HRP conjugated
1-CSB-PA650452LB01MO
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against Cd163. Recognizes Cd163 from Mouse. This antibody is HRP conjugated. Tested in the following application: ELISA

Cd163 Antibody, FITC conjugated
1-CSB-PA650452LC01MO
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against Cd163. Recognizes Cd163 from Mouse. This antibody is FITC conjugated. Tested in the following application: ELISA

Cd163 Antibody, Biotin conjugated
1-CSB-PA650452LD01MO
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against Cd163. Recognizes Cd163 from Mouse. This antibody is Biotin conjugated. Tested in the following application: ELISA

Mouse CD163 shRNA Plasmid
20-abx979200
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

CD163(M130/1240) Antibody
BNCAP1240-100 100uL
EUR 238.8
Description: Primary antibody against CD163(M130/1240), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

CD163(M130/1240) Antibody
BNCAP1240-500 500uL
EUR 652.8
Description: Primary antibody against CD163(M130/1240), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

CD163(M130/1240) Antibody
BNCP1240-250 250uL
EUR 459.6
Description: Primary antibody against CD163(M130/1240), PerCP conjugate, Concentration: 0.1mg/mL

CD163(M130/1240) Antibody
BNCR1240-250 250uL
EUR 459.6
Description: Primary antibody against CD163(M130/1240), RPE conjugate, Concentration: 0.1mg/mL

CD163(M130/1240) Antibody
BNC941240-100 100uL
EUR 238.8
Description: Primary antibody against CD163(M130/1240), CF594 conjugate, Concentration: 0.1mg/mL

CD163(M130/1240) Antibody
BNC941240-500 500uL
EUR 652.8
Description: Primary antibody against CD163(M130/1240), CF594 conjugate, Concentration: 0.1mg/mL

CD163(M130/1240) Antibody
BNCA1240-250 250uL
EUR 459.6
Description: Primary antibody against CD163(M130/1240), APC conjugate, Concentration: 0.1mg/mL

CD163(M130/1240) Antibody
BNC811240-100 100uL
EUR 238.8
Description: Primary antibody against CD163(M130/1240), CF680R conjugate, Concentration: 0.1mg/mL

CD163(M130/1240) Antibody
BNC811240-500 500uL
EUR 652.8
Description: Primary antibody against CD163(M130/1240), CF680R conjugate, Concentration: 0.1mg/mL

CD163(M130/1240) Antibody
BNUB1240-100 100uL
EUR 250.8
Description: Primary antibody against CD163(M130/1240), Concentration: 0.2mg/mL

CD163(M130/1240) Antibody
BNUB1240-500 500uL
EUR 549.6
Description: Primary antibody against CD163(M130/1240), Concentration: 0.2mg/mL

CD163(M130/1240) Antibody
BNCH1240-100 100uL
EUR 238.8
Description: Primary antibody against CD163(M130/1240), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

CD163(M130/1240) Antibody
BNCH1240-500 500uL
EUR 652.8
Description: Primary antibody against CD163(M130/1240), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

CD163(M130/1240) Antibody
BNC881240-100 100uL
EUR 238.8
Description: Primary antibody against CD163(M130/1240), CF488A conjugate, Concentration: 0.1mg/mL

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